Results 1 to 10 of about 9,624 (181)

A prognostic index model for assessing the prognosis of ccRCC patients by using the mRNA expression profiles of AIF1L, SERPINC1 and CES1 [PDF]

open access: yesJournal of Men's Health, 2022
Background: Kidney carcinoma is a major cause of carcinoma-related death, with the prognosis for advanced or metastatic renal cell carcinoma still very poor.
Song Zheng   +20 more
doaj   +1 more source

Identification of candidate biomarker EMP3 and its prognostic potential in clear cell renal cell carcinoma

open access: yesFrontiers in Bioscience-Landmark, 2021
Background: Clear cell renal cell carcinoma (ccRCC) is considered the second most common urogenital tract carcinoma, plaguing patients worldwide due to its high incidence and resistance to treatment.
Qingyang Lv   +8 more
doaj   +1 more source

MIIP inhibits clear cell renal cell carcinoma proliferation and angiogenesis via negative modulation of the HIF-2α-CYR61 axis

open access: yesCancer Biology & Medicine, 2022
Objective: In various cancers, migration and invasion inhibitory protein (MIIP) is expressed at low level and is involved in cancer pathogenesis. Herein, we sought to explore the function of MIIP in clear cell renal cell carcinoma (ccRCC). Methods: CCK-8,
Fengqi Yan   +14 more
doaj   +1 more source

Clinical utility of MCM2 and CD44 expression in clear cell renal cell carcinoma

open access: yesPolish Journal of Pathology, 2021
Clear cell renal cell carcinoma (ccRCC) has an unpredictable clinical consequence even with the use of usual prognostic factors. To determine whether utilization of cell proliferation and cell adhesion by using MCM2 and CD44 immuno-expression could ...
Mariana F. Gayyed   +2 more
doaj   +1 more source

NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma

open access: yesCancer Biology & Therapy, 2023
In clear cell renal cell carcinoma (ccRCC), activation of hypoxic signaling induces NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 (NDUFA4L2) expression.
Jaclyn M. Kubala   +9 more
doaj   +1 more source

Soluble forms of PD-L1 and PD-1 as prognostic and predictive markers of sunitinib efficacy in patients with metastatic clear cell renal cell carcinoma

open access: yesOncoImmunology, 2020
Metastatic clear cell renal cell carcinoma (mccRCC) benefits from several treatment options in the first-line setting with VEGFR inhibitors and/or immunotherapy including anti-PD-L1 or anti-PD1 agents.
Christopher Montemagno   +13 more
doaj   +1 more source

circRNA DENND1B inhibits tumorigenicity of clear cell renal cell carcinoma via miR-122-5p/TIMP2 axis

open access: yesOpen Medicine, 2022
Clear cell renal cell carcinoma (ccRCC) is the most common type of renal cancers. However, circ_DENND1B has not been studied yet. GSE100186 dataset was used for the level analysis of circ_DENND1B.
Chen Deqiang   +4 more
doaj   +1 more source

Variation in the gene encoding the co-inhibitory molecule BTLA is associated with survival in patients treated for clear cell renal carcinoma – results of a prospective cohort study

open access: yesArchives of Medical Science, 2021
Introduction The successful introduction of immune checkpoint blockade approaches to renal-cell carcinoma (RCC) treatment indicates the importance of molecules regulating the T cell response to RCC risk and progression.
Krzysztof Tupikowski   +7 more
doaj   +1 more source

Basic Characteristics and Survival Outcomes of Asian-American Patients with Clear Cell Renal Cell Carcinoma and Comparisons with White Patients: A Population-Based Analysis

open access: yesInternational Journal of General Medicine, 2021
Xiao Li,1,* Zicheng Xu,1,* Ting Xu,1,* Feng Qi,1 Ninghong Song2 1Department of Urology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, 210009, People’s ...
Li X, Xu Z, Xu T, Qi F, Song N
doaj  

Macrophage-Specific Cathepsin as a Marker Correlated with Prognosis and Tumor Microenvironmental Characteristics of Clear Cell Renal Cell Carcinoma

open access: yesJournal of Inflammation Research, 2022
Fan Zhang,1,* Jiayu Liang,1 You Lu,2,* Yongquan Tang,3 Shengzhuo Liu,1 Kan Wu,1 Fuxun Zhang,1 Yiping Lu,1 Zhihong Liu,1 Xianding Wang1 1Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, People ...
Zhang F   +9 more
doaj  

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