Results 31 to 40 of about 23,244 (239)

Expression of PLAUR in ccRCC and methylation study.

, 2022
A-F. Analysis of PLAUR expression and prognosis in ccRCC; G-J. Analysis of methylation levels and prognostic correlation of PLAUR in ccRCC.
Zengshu Xing (12837293), Zhiwei Wang (120259), Kunxiong Wang (12837290), Xin Gao (14001), Zhenxiang Liu (534118)   +4 more
core   +1 more source

Does the Urinary Proteome Reflect ccRCC Stage and Grade Progression? [PDF]

, 2021
Due its ability to provide a global snapshot of kidney physiology, urine has emerged as a highly promising, non-invasive source in the search for new molecular indicators of disease diagnosis, prognosis, and surveillance.
Grasso A, Magni F., Piga I, Smith A, Stella M, Chinello C, Grasso M, Bovo G, Santorelli L, Capitoli G   +9 more
core   +2 more sources

Prognostic role of the beta-2 adrenergic receptor in clear cell renal cell carcinoma

Animal Cells and Systems, 2019
The beta-2 adrenergic receptor (ADRB2) regulates the proliferation, apoptosis, angiogenesis, migration, and metastasis of cancer cells. However, its function in the progression of clear cell renal cell carcinoma (ccRCC) is unknown.
Mihyang Ha, Dong Woo Kim, Jayoung Kim, Chae Mi Hong, Su Min Park, In Ae Woo, Min Yong Kim, Hyunjun Koo, Jin Namkoong, Jaehyun Kim, Myoung-Eun Han, Parkyong Song, Jin Hur, Chi-Dug Kang, Yun Hak Kim, Dongjun Lee, Sae-Ock Oh   +16 more
doaj   +1 more source

Single-cell RNA-sequencing analysis reveals MYH9 promotes renal cell carcinoma development and sunitinib resistance via AKT signaling pathway

Cell Death Discovery, 2022
Clear cell renal cell carcinoma (ccRCC) is a serious threat to human health worldwide, while its heterogeneity limits therapeutic success and leads to poor survival outcomes.
Zhipeng Xu, Min Liu, Jin Wang, Kai Liu, Liuyu Xu, Demin Fan, Hui Zhang, Wenxin Hu, Dan Wei, Jianning Wang   +9 more
doaj   +1 more source

PRR11 promotes ccRCC tumorigenesis by regulating E2F1 stability [PDF]

JCI Insight, 2021
Proline rich 11 (PRR11), a novel tumor-related gene, has been identified in different tumors. However, the relevant biological functions of PRR11 in human clear cell renal cell carcinoma (ccRCC) have not been studied. In this study, we first identified PRR11 as a biomarker of ccRCC and predictor of poor prognosis by bioinformatics.
Siming Chen, Zhiwen He, Tianchen Peng, Fenfang Zhou, Gang Wang, Kaiyu Qian, Lingao Ju, Yu Xiao, Xinghuan Wang   +8 more
openaire   +3 more sources

DataSheet_7_Cuproptosis in ccRCC: key player in therapeutic and prognostic targets.zip

, 2023
BackgroundClassical biomarkers have been used to classify clear cell renal cell carcinoma (ccRCC) patients in a variety of ways, and emerging evidences have indicated that cuproptosis is closely related to mitochondrial metabolism, thereby accelerating ...
Shaohua He (13202703), Chao Qin (119135), Zhongwen Lu (10134056), Qiang Li (8118), Hongqi Chen (425987), Yang Lv (279176), Lu Yin (183747)   +6 more
core   +1 more source

Screening and identification of prognostic genes associated with eosinophilic features of clear cell renal cell carcinoma

Heliyon, 2023
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma, which is characterized by transparent cytoplasm. However, some ccRCC also show eosinophilic cytoplasm, and the molecular difference between eosinophilic and clear
Tuanjie Guo, Liren Jiang, Tao Wang, Jian Zhang, Yang Liu, Xuan Wang, Ning Zhang, Siteng Chen, Xiang Wang   +8 more
doaj   +1 more source

Structural Genomics Defines PBRM1 Bromodomain Variant Function in ccRCC. [PDF]

Hum Mutat
Polybromo‐1 (PBRM1) modulates chromatin accessibility and transcription via six bromodomains that bind acetyl‐lysine residues on nuclear proteins. PBRM1 variants exist in ~40% of clear cell renal cell carcinoma (ccRCC) cases.
Bursch KL, Jorge SD, Catlin AE, Nuñez R, LeClaire MD, Licklider J, Urrutia RA, Smith BC.   +7 more
europepmc   +2 more sources

DataSheet_8_Cuproptosis in ccRCC: key player in therapeutic and prognostic targets.zip

, 2023
BackgroundClassical biomarkers have been used to classify clear cell renal cell carcinoma (ccRCC) patients in a variety of ways, and emerging evidences have indicated that cuproptosis is closely related to mitochondrial metabolism, thereby accelerating ...
Shaohua He (13202703), Chao Qin (119135), Zhongwen Lu (10134056), Qiang Li (8118), Hongqi Chen (425987), Yang Lv (279176), Lu Yin (183747)   +6 more
core   +1 more source

PBX1, EMCN and ERG are associated with the sub-clusters and the prognosis of VHL mutant clear cell renal cell carcinoma

Scientific Reports, 2022
The molecular heterogeneity of primary clear cell renal cell carcinoma (ccRCC) has been reported. However, the classifications of Von Hippel–Lindau (VHL) mutant ccRCC are unclear.
Haiwei Wang, Xinrui Wang, Liangpu Xu, Ji Zhang   +3 more
doaj   +1 more source