Results 1 to 10 of about 154,294 (167)
Chromoanagenesis landscape in 10,000 TCGA patients [PDF]
Cancers, 2021 Abstract During the past decade, whole-genome sequencing of tumor biopsies and individuals with congenital disorders highlighted the phenomenon of chromoanagenesis, a single chaotic event of chromosomal rearrangement. Chromoanagenesis was shown to be frequent in many types of cancers, to occur in early stages of cancer development, and ...
Roni Rasnic, Michal Linial
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Morphometic analysis of TCGA glioblastoma multiforme [PDF]
BMC Bioinformatics, 2011 AbstractBackgroundOur goals are to develop a computational histopathology pipeline for characterizing tumor types that are being generated by The Cancer Genome Atlas (TCGA) for genomic association. TCGA is a national collaborative program where different tumor types are being collected, and each tumor is being characterized using a variety of genome ...
Chang, Hang +7 more
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TCGA-Assembler: open-source software for retrieving and processing TCGA data [PDF]
Nature Methods, 2014 To the Editor: The Cancer Genome Atlas (TCGA) has been generating multi-modal genomics, epigenomics, and proteomics data for thousands of tumor samples across more than 20 types of cancer. While the access to most level-1 and -2 TCGA data is restricted, the entire level-3 TCGA data as well as some level-1 clinical data (e.g., survival and drug ...
Yitan, Zhu, Peng, Qiu, Yuan, Ji
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TCGA-assembler 2: software pipeline for retrieval and processing of TCGA/CPTAC data [PDF]
Bioinformatics, 2017 Abstract Motivation The Cancer Genome Atlas (TCGA) program has produced huge amounts of cancer genomics data providing unprecedented opportunities for research. In 2014, we developed TCGA-Assembler, a software pipeline for retrieval and processing of public TCGA data.
Lin Wei +5 more
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Zhongliu Fangzhi Yanjiu, 2020 Objective To construct a risk model for predicting the prognosis of papillary thyroid carcinoma (PTC) patients based on the expression of microRNAs (miRNA).
JIAO Zhaoshuang, ZHANG Huainian
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Prognostic Role of Immune-related Genes in Hepatocellular Carcinoma
Zhongliu Fangzhi Yanjiu, 2022 Objective To identify the potential prognostic biomarkers of the immune-related genes signature for patients with hepatocellular carcinoma (HCC). Methods Original HCC data were downloaded from TCGA, and the immune activity of each sample was calculated ...
WANG Jue +8 more
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Frontiers in Bioscience-Landmark, 2023 Background: The purpose of our study is to analyze the expression pattern and prognostic value of catabolism-related enzymes of branched-chain amino acids (BCAAs) in non-small cell lung cancer (NSCLC). Methods: Differential expression analysis, mutation,
Xiaojun Yao +4 more
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Frontiers in Bioscience-Landmark, 2023 Background: High-grade serous ovarian cancer (HGSOC) treatment is facing clinical challenges. The tumor immune microenvironment (TME) has recently been shown to perform a critical function in the prediction of clinical outcomes as well as the ...
Junping Pan +9 more
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Journal of Virology, 2015 ABSTRACT Next-generation sequencing results obtained to detect somatic mutations in human cancers can also be searched for viruses that contribute to cancer. Recently, human papillomavirus 18 RNA was detected in tumor types not typically associated with HPV infection.
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TCGA Expedition: A Data Acquisition and Management System for TCGA Data
PLOS ONE, 2016 The Cancer Genome Atlas Project (TCGA) is a National Cancer Institute effort to profile at least 500 cases of 20 different tumor types using genomic platforms and to make these data, both raw and processed, available to all researchers. TCGA data are currently over 1.2 Petabyte in size and include whole genome sequence (WGS), whole exome sequence ...
Uma R Chandran +14 more
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