Results 1 to 10 of about 924,560 (254)

UCHL1 acts as a potential oncogene and affects sensitivity of common anti-tumor drugs in lung adenocarcinoma

open access: yesWorld Journal of Surgical Oncology, 2022
Background Lung adenocarcinoma is the leading cause of cancer death worldwide. Recently, ubiquitin C-terminal hydrolase L1 (UCHL1) has been demonstrated to be highly expressed in many tumors and plays the role of an oncogene.
Jianbo Yao   +9 more
doaj   +1 more source

ARNTL2 is an indicator of poor prognosis, promotes epithelial-to-mesenchymal transition and inhibits ferroptosis in lung adenocarcinoma

open access: yesTranslational Oncology, 2022
Objectives: ARNTL2, as a circadian transcription factor, has been recently proposed to play an important role in a variety of tumors. however, the role of ARNTL2 in lung carcinogenesis and progression remains unclear.
Huan Zhang   +10 more
doaj   +1 more source

Veillonella parvula promotes the proliferation of lung adenocarcinoma through the nucleotide oligomerization domain 2/cellular communication network factor 4/nuclear factor kappa B pathway

open access: yesDiscover Oncology, 2023
Enrichment of Veillonella parvula in the lung microbiota is strongly associated with non-small cell lung cancer (NSCLC) and induces the progression of lung adenocarcinoma in vivo, but its actual role and mechanism remain unexplored.
Wen Zeng   +7 more
doaj   +1 more source

Follistatin is a novel biomarker for lung adenocarcinoma in humans. [PDF]

open access: yesPLoS ONE, 2014
Follistatin (FST), a single chain glycoprotein, is originally isolated from follicular fluid of ovary. Previous studies have revealed that serum FST served as a biomarker for pregnancy and ovarian mucinous tumor.
Fangfang Chen   +7 more
doaj   +1 more source

Effects of lncRNA PKD2-2-3 on cell proliferation, clone formation, migration, and invasion of lung adenocarcinoma [PDF]

open access: yesZhongguo aizheng zazhi, 2023
Background and purpose: Long non-coding RNA (lncRNA) is abnormally expressed in lung adenocarcinoma patients, and closely related to tumor occurrence, development and chemotherapy resistance.
JIA Liqing, GE Xiaolu, JIANG Lin, ZHOU Xiaoyan
doaj   +3 more sources

Hepatoid adenocarcinoma of the lung

open access: yesAutopsy and Case Reports, 2013
Lung adenocarcinomas with a mixture of tubular or papillary pattern, sheet-like or trabecular architecture, eosinophilic cytoplasm with centrally located nuclei and alpha-fetoprotein-producing cells have been described as hepatoid adenocarcinomas.
Livia Barreira Cavalcante   +3 more
openaire   +3 more sources

EGFR Mutation Status in Uighur Lung Adenocarcinoma Patients

open access: yesChinese Journal of Lung Cancer, 2013
Background and objective Epidermal growth factor receptor (EGFR), a transmembrane protein, is a member of the tyrosine kinase family. Gefitinib, an EGFR tyrosine-kinase inhibitors, has shown a high response rate in the treatment of lung cancer in ...
Li SHAN   +4 more
doaj   +1 more source

GMDS knockdown impairs cell proliferation and survival in human lung adenocarcinoma

open access: yesBMC Cancer, 2018
Background Lung adenocarcinoma is the most common type of lung cancer and one of the most lethal and prevalent cancers. Aberrant glycosylation was common and essential in tumorigenesis, with fucosylation as one of the most common types disrupted in ...
Xing Wei   +6 more
doaj   +1 more source

Long noncoding RNA expression profiles of lung adenocarcinoma ascertained by microarray analysis. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND:Long noncoding RNAs (lncRNAs) have been shown to be involved in the development and progression of lung cancer. However, the roles of lncRNAs in lung cancer are not well understood.
Gang Xu   +9 more
doaj   +1 more source

Progesterone/Org inhibits lung adenocarcinoma cell growth via membrane progesterone receptor alpha

open access: yesThoracic Cancer, 2020
Background The aim of this study was to determine whether progesterone could inhibit the growth of lung adenocarcinoma cells via membrane progesterone receptor alpha (mPRα) and elucidate its potential mechanism.
Jian Xiao   +7 more
doaj   +1 more source

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