Results 11 to 20 of about 300,691 (256)

Expression, prognostic value of CBX3 in lung adenocarcinoma and its effect on biological behavior of cancer cells [PDF]

open access: yesZhongguo aizheng zazhi, 2022
Background and purpose: Chromobox 3 (CBX3), an important component of chromatin, is involved in the development and progression of various cancers. However, the expression and role of CBX3 in lung adenocarcinoma are still unclear.
HOU Qinghua, ZHONG Yanfeng, LIU Linzhuang, WU Liusheng, LIU Jixian
doaj   +3 more sources

miR-625-5p promotes proliferation and invasion of lung adenocarcinoma by targeting PRKACA [PDF]

open access: yesZhongguo aizheng zazhi, 2021
Background and purpose: Lung adenocarcinoma is a subtype of non-small cell lung cancer. Although much progress has been made in the diagnosis and treatment of lung adenocarcinoma, the clinical prognosis and overall survival of advanced lung  ...
HU Yaqiong , BAI Jun , CHEN Lin , CHEN Xinlu , ZHANG Liping , ZHOU Dandan , WANG Yu , YIN Chonggao , LI Hongli , LIU Yuqing
doaj   +3 more sources

ARNTL2 is an indicator of poor prognosis, promotes epithelial-to-mesenchymal transition and inhibits ferroptosis in lung adenocarcinoma

open access: yesTranslational Oncology, 2022
Objectives: ARNTL2, as a circadian transcription factor, has been recently proposed to play an important role in a variety of tumors. however, the role of ARNTL2 in lung carcinogenesis and progression remains unclear.
Huan Zhang   +10 more
doaj   +1 more source

UCHL1 acts as a potential oncogene and affects sensitivity of common anti-tumor drugs in lung adenocarcinoma

open access: yesWorld Journal of Surgical Oncology, 2022
Background Lung adenocarcinoma is the leading cause of cancer death worldwide. Recently, ubiquitin C-terminal hydrolase L1 (UCHL1) has been demonstrated to be highly expressed in many tumors and plays the role of an oncogene.
Jianbo Yao   +9 more
doaj   +1 more source

Veillonella parvula promotes the proliferation of lung adenocarcinoma through the nucleotide oligomerization domain 2/cellular communication network factor 4/nuclear factor kappa B pathway

open access: yesDiscover Oncology, 2023
Enrichment of Veillonella parvula in the lung microbiota is strongly associated with non-small cell lung cancer (NSCLC) and induces the progression of lung adenocarcinoma in vivo, but its actual role and mechanism remain unexplored.
Wen Zeng   +7 more
doaj   +1 more source

Follistatin is a novel biomarker for lung adenocarcinoma in humans. [PDF]

open access: yesPLoS ONE, 2014
Follistatin (FST), a single chain glycoprotein, is originally isolated from follicular fluid of ovary. Previous studies have revealed that serum FST served as a biomarker for pregnancy and ovarian mucinous tumor.
Fangfang Chen   +7 more
doaj   +1 more source

Effects of lncRNA PKD2-2-3 on cell proliferation, clone formation, migration, and invasion of lung adenocarcinoma [PDF]

open access: yesZhongguo aizheng zazhi, 2023
Background and purpose: Long non-coding RNA (lncRNA) is abnormally expressed in lung adenocarcinoma patients, and closely related to tumor occurrence, development and chemotherapy resistance.
JIA Liqing, GE Xiaolu, JIANG Lin, ZHOU Xiaoyan
doaj   +3 more sources

EGFR Mutation Status in Uighur Lung Adenocarcinoma Patients

open access: yesChinese Journal of Lung Cancer, 2013
Background and objective Epidermal growth factor receptor (EGFR), a transmembrane protein, is a member of the tyrosine kinase family. Gefitinib, an EGFR tyrosine-kinase inhibitors, has shown a high response rate in the treatment of lung cancer in ...
Li SHAN   +4 more
doaj   +1 more source

GMDS knockdown impairs cell proliferation and survival in human lung adenocarcinoma

open access: yesBMC Cancer, 2018
Background Lung adenocarcinoma is the most common type of lung cancer and one of the most lethal and prevalent cancers. Aberrant glycosylation was common and essential in tumorigenesis, with fucosylation as one of the most common types disrupted in ...
Xing Wei   +6 more
doaj   +1 more source

Hepatoid adenocarcinoma of the lung

open access: yesAutopsy and Case Reports, 2013
Lung adenocarcinomas with a mixture of tubular or papillary pattern, sheet-like or trabecular architecture, eosinophilic cytoplasm with centrally located nuclei and alpha-fetoprotein-producing cells have been described as hepatoid adenocarcinomas.
Livia Barreira Cavalcante   +3 more
openaire   +3 more sources

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