Results 11 to 20 of about 2,224,563 (253)

Immune Resistance in Lung Adenocarcinoma [PDF]

Cancers, 2021
Lung cancer is the leading cancer killer worldwide, imposing grievous challenges for patients and clinicians. The incidence of lung adenocarcinoma (LUAD), the main histologic subtype of lung cancer, is still increasing in current-, ex-, and even non-smokers, whereas its five-year survival rate is approximately 15% as the vast majority of patients ...
Magda Spella, Georgios T. Stathopoulos
openaire   +4 more sources

Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma

Cell, 2020
Summary To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic opportunities, we performed comprehensive proteogenomic characterization of 110 tumors and 101 matched normal adjacent tissues (NATs) incorporating genomics ...
Michael A Gillette, Shankha Satpathy, Saravana M Dhanasekaran   +2 more
exaly   +2 more sources

Integrative Proteomic Characterization of Human Lung Adenocarcinoma

Cell, 2020
Genomic studies of lung adenocarcinoma (LUAD) have advanced our understanding of the disease's biology and accelerated targeted therapy. However, the proteomic characteristics of LUAD remain poorly understood.
Jun-Yu Xu, Xiang Wang, Yousheng Mao
exaly   +2 more sources

International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma

Journal of Thoracic Oncology, 2011
Introduction: Adenocarcinoma is the most common histologic type of lung cancer. To address advances in oncology, molecular biology, pathology, radiology, and surgery of lung adenocarcinoma, an international multidisciplinary classification was sponsored ...
William D Travis, Masayuki Noguchi, Andrew G Nicholson   +2 more
exaly   +2 more sources

A Grading System for Invasive Pulmonary Adenocarcinoma: A Proposal From the International Association for the Study of Lung Cancer Pathology Committee

Journal of Thoracic Oncology, 2020
Introduction: A grading system for pulmonary adenocarcinoma has not been established. The International Association for the Study of Lung Cancer pathology panel evaluated a set of histologic criteria associated with prognosis aimed at establishing a ...
André L Moreira, Yuhe Xia, Prudence A Russell   +2 more
exaly   +2 more sources

Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses

Cell, 2017
Yonit Lavin, Andrew Leader, El-Ad David Amir   +2 more
exaly   +2 more sources

Hepatoid Adenocarcinoma of the Lung [PDF]

Technology in Cancer Research & Treatment, 2021
Hepatoid adenocarcinoma of the lung (HAL) is an comparatively rare malignant tumor originating from the lung with shorter survival. HAL morphologically and pathologically exhibits hepatocellular carcinoma (HCC)-like characteristics, while its clinical features resemble pulmonary adenocarcinoma.
Meihui Li, Ying Fan, Hongyang Lu
openaire   +3 more sources

Lung Adenocarcinoma

Kanchustambham V, Sharma S.
europepmc   +5 more sources

Lung adenocarcinoma promotion by air pollutants

Nature, 2023
A complete understanding of how exposure to environmental substances promotes cancer formation is lacking. More than 70 years ago, tumorigenesis was proposed to occur in a two-step process: an initiating step that induces mutations in healthy cells ...
William Hill, Emilia L. Lim, C. Weeden, Claudia Lee, M. Augustine, Kezhong Chen, F. Kuan, F. Marongiu, E. J. Evans, D. Moore, F. S. Rodrigues, O. Pich, B. Bakker, H. Cha, R. Myers, F. van Maldegem, J. Boumelha, S. Veeriah, A. Rowan, C. Naceur-Lombardelli, T. Karasaki, Monica Sivakumar, Swapnanil De, D. Caswell, Ai Nagano, James R. M. Black, Carlos Martínez-Ruiz, M. Ryu, Ryan D. Huff, Shijian Li, M. Favé, Alastair Magness, A. Suárez‐Bonnet, S. Priestnall, M. Lüchtenborg, K. Lavelle, Joanna Pethick, Steven I Hardy, F. McRonald, Meng-Hung Lin, Clara I. Troccoli, Moumita Ghosh, Y. Miller, D. Merrick, R. Keith, M. Al Bakir, Chris Bailey, M. Hill, L. Saal, Yilun Chen, A. George, C. Abbosh, N. Kanu, Se-Hoon Lee, N. Mcgranahan, C. Berg, P. Sasieni, R. Houlston, C. Turnbull, Stephen Lam, P. Awadalla, E. Grönroos, J. Downward, T. Jacks, C. Carlsten, I. Malanchi, A. Hackshaw, K. Litchfield, Jason F. Amrita Apostolos Azmina Keng Mohamad Mohammed F Lester Bajaj Nakas Sodha-Ramdeen Ang Tufail Chowdh, Jason Lester, A. Bajaj, A. Nakas, Azmina Sodha-Ramdeen, K. Ang, M. Tufail, M. F. Chowdhry, M. Scotland, R. Boyles, S. Rathinam, Claire Wilson, Domenic Marrone, S. Dulloo, D. Fennell, Gurdeep Matharu, J. Shaw, Joan Riley, L. Primrose, E. Boleti, Heather Cheyne, Mohammed Khalil, S. Richardson, Tracey Cruickshank, Gillian Price, K. Kerr, S. Benafif, Kayleigh Gilbert, B. Naidu, Akshay J. Patel, A. Osman, Christer Lacson, G. Langman, Helen Shackleford, M. Djearaman, S. Kadiri, Gary Middleton, Angela E. Leek, Jack Davies Hodgkinson, Nicola Totten, A. Montero, E. Smith, E. Fontaine, F. Granato, H. Doran, Juliette Novasio, K. Rammohan, L. Joseph, P. Bishop, R. Shah, Stuart Moss, Vijay Joshi, P. Crosbie, F. Gomes, Kate Brown, M. Carter, A. Chaturvedi, L. Priest, P. Oliveira, C. Lindsay, F. Blackhall, M. Krebs, Y. Summers, A. Clipson, J. Tugwood, Alastair Kerr, D. Rothwell, E. Kilgour, C. Dive, H. Aerts, R. Schwarz, Tom L. Kaufmann, G. Wilson, R. Rosenthal, P. van Loo, Nicolai J. Birkbak, Z. Szallasi, Judit Kisistók, M. Sokač, Roberto Salgado, M. Dióssy, J. Demeulemeester, Abigail Bunkum, A. Stewart, A. Frankell, A. Karamani, A. Toncheva, A. Huebner, B. Chain, B. Campbell, Carla Castignani, C. Puttick, Corentin Richard, C. Hiley, D. Pearce, D. Karagianni, D. Biswas, D. Levi, Elena Hoxha, E. L. Cadieux, E. Colliver, E. Nye, F. Gálvez-Cancino, Foteini Athanasopoulou, F. Gimeno-Valiente, G. Kassiotis, Georgia Stavrou, Gerasimos Mastrokalos, Haoran Zhai, H. Lowe, Ignacio Matos, J. Goldman, J. Reading, Javier Herrero, J. Rane, J. Nicod, J. Lam, J. Hartley, K. Peggs, Katey S. S. Enfield, Kayalvizhi Selvaraju, K. Thol, K. Ng, K. Dijkstra, Kristiana Grigoriadis, K. Thakkar, L. Ensell, Mansi Shah, Mar Durán, Maria Litovchenko, M. W. Sunderland, M. Dietzen, Michelle M. Leung, M. Escudero, Mihaela Angelova, M. Tanić, O. Chervova, O. Lucas, O. Al-Sawaf, Paulina Prymas, P. Hobson, Piotr Pawlik, R. Stone, R. Bentham, R. Hynds, R. Vendramin, S. Saghafinia, Saioa López, Samuel Gamble, S. Ung, S. Quezada, S. Vanloo, Simone Zaccaria, S. Hessey, S. Ward, S. Boeing, Stephan Beck, S. Bola, Tamara Denner, T. Marafioti, Thanos P. Mourikis, T. Watkins, V. Spanswick, Vittorio Barbè, Wei-Ting Lu, Wing-Kin Liu, Yin Wu, Yutaka Naito, Z. Ramsden, C. Veiga, G. Royle, C. Collins-Fekete, F. Fraioli, P. Ashford, T. Clark, Martin D. Forster, Siow-Ming Lee, E. Borg, M. Falzon, D. Papadatos-Pastos, James Wilson, T. Ahmad, A. Procter, Asia Ahmed, Magali N. Taylor, A. Nair, D. Lawrence, D. Patrini, N. Navani, R. Thakrar, S. Janes, E. M. Hoogenboom, Fleur Monk, James W. Holding, Junaid Choudhary, Kunal Bhakhri, M. Scarci, M. Hayward, N. Panagiotopoulos, Pat Gorman, R. Khiroya, R. Stephens, Y. Wong, S. Bandula, A. Sharp, Sean Smith, N. Gower, H. Dhanda, Kitty Chan, Camilla Pilotti, R. Leslie, Anca-Ioana Grapa, Hanyun Zhang, K. AbdulJabbar, Xiaoxi Pan, Yinyin Yuan, D. Chuter, M. Mackenzie, S. Chee, A. Alzetani, J. Cave, Lydia Scarlett, J. Richards, Papawadee Ingram, S. Austin, Eric Lim, P. De Sousa, S. Jordan, A. Rice, H. Raubenheimer, H. Bhayani, L. Ambrose, A. Devaraj, Hema Chavan, S. Begum, S. Buderi, Daniel Kaniu, Mpho Malima, S. Booth, A. Nicholson, Nádia Fernandes, P. Shah, C. Proli, M. Hewish, S. Danson, M. Shackcloth, Lily Robinson, P. Russell, K. Blyth, C. Dick, J. Le Quesne, A. Kirk, M. Asif, R. Bilancia, N. Kostoulas, Mathew Thomas, J. DeGregori, M. Jamal-Hanjani, C. Swanton   +326 more
semanticscholar   +1 more source

STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma

Nature, 2023
STING signalling is activated in metastatic cancer cells that exit from an immune-evasive dormant state, blocking their progression and cancer relapse. Metastasis frequently develops from disseminated cancer cells that remain dormant after the apparently
Jing Hu, Francisco J. Sánchez-Rivera, Zhenghan Wang, Gabriela N. Johnson, Yu-jui Ho, K. Ganesh, S. Umeda, Siting Gan, Adriana M. Mujal, Rebecca B Delconte, Jessica P. Hampton, Huiyong Zhao, Sanjay V. Kottapalli, E. de Stanchina, C. Iacobuzio-Donahue, D. Pe’er, S. Lowe, Joseph C. Sun, J. Massagué   +18 more
semanticscholar   +1 more source