Results 21 to 30 of about 2,224,563 (253)

Adenocarcinoma of the lung [PDF]

Thorax, 1969
The clinical and histological features of 53 cases of adenocarcinoma of the lung are presented. In more than one-third of the patients the tumour was a solitary nodule, raising the possibility that it might be a metastatic focus. Although histological features may suggest an origin from such sources as the kidney, uterus, ovary or bowel, nearly all ...
J R, Hinds, G C, Hitchcock
openaire   +2 more sources

Multiple Omics Analysis of the Role of RBM10 Gene Instability in Immune Regulation and Drug Sensitivity in Patients with Lung Adenocarcinoma (LUAD)

Biomedicines, 2023
Objective: The RNA-binding protein RBM10 can regulate apoptosis during the proliferation and migration of pancreatic cancer, endometrial cancer, and osteosarcoma cells; however, the molecular mechanism underlying lung adenocarcinoma is rarely reported ...
Liusheng Wu, Qi Liu, X-J Ruan, Xinyu Luan, Yanfeng Zhong, Jixian Liu, Jun Yan, Xiaoqiang Li   +7 more
semanticscholar   +1 more source

Hepatoid adenocarcinoma of the lung [PDF]

QJM, 2016
Learning Point for Clinicians Hepatoid adenocarcinoma of lung is a rare type of lung cancer which is defined as an α-fetoprotein—producing primary carcinoma with morphological features similar to hepatocellular carcinoma. Establishing the diagnosis of HAL is worthwhile because of the potential for altered management. A 79-year-old Chinese male smoker
G-Q, Qian, F-Y, Yin, G-X, Li, J-G, Chu
openaire   +2 more sources

Regulation of Ferroptosis in Lung Adenocarcinoma

International Journal of Molecular Sciences, 2023
Lung adenocarcinoma (LUAD) is the most common lung cancer, which accounts for about 35–40% of all lung cancer patients. Despite therapeutic advancements in recent years, the overall survival time of LUAD patients still remains poor, especially KRAS ...
Xiangyun Wei, Xiaohe Li, Shuming Hu, Jinke Cheng, Rong Cai   +4 more
semanticscholar   +1 more source

Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma

Cancer Communications, 2022
Resistance to ferroptosis, a regulated cell death caused by iron‐dependent excessive accumulation of lipid peroxides, has recently been linked to lung adenocarcinoma (LUAD).
Xiao Zhang, Yunhua Xu, Lifang Ma, Keke Yu, Yongjie Niu, Xin Xu, Yi Shi, Susu Guo, Xiangfei Xue, Yikun Wang, Shiyu Qiu, Jiangtao Cui, Hong Wang, Xiaoting Tian, Y. Miao, F. Meng, Y. Qiao, Y. Yu, Jiayi Wang   +18 more
semanticscholar   +1 more source

Delineating the dynamic evolution from preneoplasia to invasive lung adenocarcinoma by integrating single-cell RNA sequencing and spatial transcriptomics

Experimental and Molecular Medicine, 2022
The cell ecology and spatial niche implicated in the dynamic and sequential process of lung adenocarcinoma (LUAD) from adenocarcinoma in situ (AIS) to minimally invasive adenocarcinoma (MIA) and subsequent invasive adenocarcinoma (IAC) have not yet been ...
Jianfei Zhu, Yue Fan, Yanlu Xiong, Wen-chen Wang, Jia-kuan Chen, Yanmin Xia, Jie Lei, Li Gong, Shiquan Sun, Tao Jiang   +9 more
semanticscholar   +1 more source

Immunomodulatory Factor TIM3 of Cytolytic Active Genes Affected the Survival and Prognosis of Lung Adenocarcinoma Patients by Multi-Omics Analysis

Biomedicines, 2022
[Objective] Using multi-omics research methods to explore cytolytic activity-related genes through the immunoregulatory factors HAVCR2 (TIM3) affecting the survival and prognosis of lung adenocarcinoma.
Liusheng Wu, Yanfeng Zhong, Dingwang Wu, Pengcheng Xu, X-J Ruan, Jun Yan, Jixian Liu, Xiaoqiang Li   +7 more
semanticscholar   +1 more source

Lung Adenocarcinoma Tumor Origin: A Guide for Personalized Medicine

Cancers, 2022
Simple Summary Lung cancer is the leading cause of cancer-related death worldwide, with an average 5-year survival rate of approximately 15%. Among the multiple histological type of lung cancer, adenocarcinoma is the most common.
L. Seguin, M. Durandy, C. Féral
semanticscholar   +1 more source

Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma

Nature Communications, 2020
Advanced metastatic cancer poses utmost clinical challenges and may present molecular and cellular features distinct from an early-stage cancer. Herein, we present single-cell transcriptome profiling of metastatic lung adenocarcinoma, the most prevalent ...
N. Kim, H. Kim, K. Lee, Yourae Hong, J. Cho, J. Choi, Jung-Il Lee, Y. Suh, B. Ku, Hye Hyeon Eum, Soyean Choi, Yoon-La Choi, Je-Gun Joung, W. Park, H. Jung, Jong-Mu Sun, Se-Hoon Lee, J. Ahn, Keunchil Park, M. Ahn, Hae-Ock Lee   +20 more
semanticscholar   +1 more source

Hedyotis diffusa injection induces ferroptosis via the Bax/Bcl2/VDAC2/3 axis in lung adenocarcinoma.

Phytomedicine, 2022
BACKGROUND Lung cancer has the highest mortality rate among all cancer types. In combination with multiple chemotherapeutic options, traditional Chinese medicine has proven indispensable for the comprehensive treatment of lung cancer.
Fuhao Huang, J. Pang, Lian Xu, W. Niu, Yaoshuai Zhang, Shanshan Li, Xian Li   +6 more
semanticscholar   +1 more source