Results 51 to 60 of about 9,624 (181)

Prognostic Value of an m5C RNA Methylation Regulator-Related Signature for Clear Cell Renal Cell Carcinoma

open access: yesCancer Management and Research, 2021
Hanrong Li,1 Huiming Jiang,2 Zhicheng Huang,2 Zhilin Chen,2 Nanhui Chen2 1Department of Extracorporeal Shock Wave Lithotripsy, Meizhou People’s Hospital (Huangtang Hospital), Meizhou, Guangdong, People’s Republic of China; 2Department of Urology, Meizhou
Li H, Jiang H, Huang Z, Chen Z, Chen N
doaj  

Model‐based clinical pharmacology profiling of subcutaneous nivolumab in renal cell carcinoma: Bridging to alternative dosing regimens and indications

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
A novel model‐informed drug development (MIDD) approach was employed to derive the coprimary endpoints (time‐averaged serum concentration over 28 days [Cavgd28] and minimum serum concentration at steady state [Cminss]) of the phase III CheckMate 67T study (NCT04810078).
Yue Zhao   +5 more
wiley   +1 more source

SAM of ccRCC tumors against the rest of them.

open access: yes, 2020
ccRCC = Clear cell renal carcinoma.
Guillermo de Velasco (3457934)   +13 more
core   +1 more source

DataSheet_6_Cuproptosis in ccRCC: key player in therapeutic and prognostic targets.zip

open access: yes, 2023
BackgroundClassical biomarkers have been used to classify clear cell renal cell carcinoma (ccRCC) patients in a variety of ways, and emerging evidences have indicated that cuproptosis is closely related to mitochondrial metabolism, thereby accelerating ...
Shaohua He (13202703)   +6 more
core   +1 more source

Sphingosine kinase 1 overexpression contributes to sunitinib resistance in clear cell renal cell carcinoma

open access: yesOncoImmunology, 2018
Sphingosine kinase 1 (SphK1) is the major source of the bioactive lipid and GPCR agonist sphingosine 1-phosphate (S1P). Although alterations in SphK1 expression and activity have been detected in various human malignancies, its potential molecular ...
Yunze Xu   +5 more
doaj   +1 more source

Heterogeneity Analyzed by CT‐Based Habitat Analysis for Clinical Management of Cancers: A Narrative Review

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tumors are highly heterogeneous, and whole‐lesion radiomics analysis is a popular method for extracting texture features that reflect this heterogeneity, which can be used to build models for cancer diagnosis, staging, therapy response evaluation, and prognosis prediction.
Yang Zhang   +2 more
wiley   +1 more source

The prognostic significance of UBE3C expression in ccRCC.

open access: yes, 2015
(A) Real-time quantitative RT-PCR analysis of UBE3C expression in ccRCC and corresponding peritumoral renal tissues. The relative expression of UBE3C mRNA in ccRCC tissue samples was higher than that in the paired peritumoral renal tissues.
Xiao Fei Wen (689906)   +6 more
core   +1 more source

Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery [PDF]

open access: yes, 2014
Background:Wider clinical applications of 9p status in clear cell renal cell carcinoma (ccRCC) are limited owing to the lack of validation and consensus for interphase fluorescent in situ hybridisation (I-FISH) scoring technique.
Fleming, S.   +15 more
core   +1 more source

Metabolic Reprogramming in Kidney Cancer: Implications for Therapy

open access: yesAnnals of Urologic Oncology
Kidney cancer, particularly clear cell renal cell carcinoma (ccRCC), has emerged as a paradigm for cancer metabolic reprogramming, exhibiting distinctive alterations that drive tumor progression and therapeutic resistance.
Elena Tena Edo
doaj   +1 more source

A Bioinformatic Analysis of Immune-Related Prognostic Genes in Clear Cell Renal Cell Carcinoma Based on TCGA and GEO Databases

open access: yesInternational Journal of General Medicine, 2022
Jianpeng Li,1– 3,* Jinlong Cao,1– 3,* Pan Li,1– 3 Ran Deng,1– 3 Zhiqiang Yao,1– 3 Lijun Ying,1– 3 Junqiang Tian1– 3 1Department of Urology, The Second Hospital of Lanzhou University, Lanzhou, People’s Republic of China; 2Key Laboratory of Gansu ...
Li J   +6 more
doaj  

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