Results 21 to 30 of about 23,244 (239)

SDHB Suppresses the Tumorigenesis and Development of ccRCC by Inhibiting Glycolysis [PDF]

open access: yesFrontiers in Oncology, 2021
Metabolic reprogramming is the prominent feature of clear cell renal cell carcinoma (ccRCC). Succinate dehydrogenase subunit B (SDHB) is one of subunits of mitochondrial respiratory chain complex II. The loss of SDHB function is closely related with metabolic changes in kidney cancer cells.
Zhiyu Fang   +3 more
openaire   +3 more sources

Basic Characteristics and Survival Outcomes of Asian-American Patients with Clear Cell Renal Cell Carcinoma and Comparisons with White Patients: A Population-Based Analysis

open access: yesInternational Journal of General Medicine, 2021
Xiao Li,1,* Zicheng Xu,1,* Ting Xu,1,* Feng Qi,1 Ninghong Song2 1Department of Urology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, 210009, People’s ...
Li X, Xu Z, Xu T, Qi F, Song N
doaj  

CA9-Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features. [PDF]

open access: yesAdv Sci (Weinh)
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Chen K   +19 more
europepmc   +2 more sources

Macrophage-Specific Cathepsin as a Marker Correlated with Prognosis and Tumor Microenvironmental Characteristics of Clear Cell Renal Cell Carcinoma

open access: yesJournal of Inflammation Research, 2022
Fan Zhang,1,* Jiayu Liang,1 You Lu,2,* Yongquan Tang,3 Shengzhuo Liu,1 Kan Wu,1 Fuxun Zhang,1 Yiping Lu,1 Zhihong Liu,1 Xianding Wang1 1Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, People ...
Zhang F   +9 more
doaj  

Integrative Analysis of the Genomic and Immune Microenvironment Characteristics Associated With Clear Cell Renal Cell Carcinoma Progression: Implications for Prognosis and Immunotherapy

open access: yesFrontiers in Immunology, 2022
Unlike early clear cell renal cell carcinoma (ccRCC), locally advanced and metastatic ccRCC present poor treatment outcomes and prognosis. As immune checkpoint inhibitors have achieved favorable results in the adjuvant treatment of metastatic ccRCC, we ...
Enyu Lin   +14 more
doaj   +1 more source

LINC01232 serves as a novel biomarker and promotes tumour progression by sponging miR-204-5p and upregulating RAB22A in clear cell renal cell carcinoma

open access: yesAnnals of Medicine, 2021
Background Long non-coding RNAs (lncRNAs) are involved in the progression of various cancers, including clear cell renal cell carcinoma (ccRCC). This study aimed to investigate the expression and prognostic value of long intergenic non-protein coding RNA
Qingling Liu, Chengbin Lei
doaj   +1 more source

Multidisciplinary Team (MDT) Discussion Improves Overall Survival Outcomes for Metastatic Renal Cell Carcinoma Patients

open access: yesJournal of Multidisciplinary Healthcare, 2023
Yuhao Zeng,1,* Sha Zhu,1,* Zilin Wang,1 Junru Chen,1 Jindong Dai,1 Zhenhua Liu,1 Guangxi Sun,1 Jiayu Liang,1 Xingming Zhang,1 Zhipeng Wang,1 Jinge Zhao,1 Yuchao Ni,1 Jiyu Yang,1 Minghao Wang,1 Qiang Wei,1 Xiang Li,1 Ni Chen,2 Zhiping Li,3 Xin ...
Zeng Y   +25 more
doaj  

Cellular milieu in clear cell renal cell carcinoma

open access: yesFrontiers in Oncology, 2022
Clear cell renal cell carcinoma (ccRCC) is globally the most prevalent renal cancer. The cells of origin in ccRCC have been identified as proximal tubular epithelial cells (PTEC); however, the transcriptomic pathways resulting in the transition from ...
Arti M. Raghubar   +20 more
doaj   +1 more source

Basic characteristics of 526 ccRCC patients.

open access: yes, 2022
Basic characteristics of 526 ccRCC patients.
Tie Chong (655561)   +8 more
core   +1 more source

Pan-Cancer Transcriptomic Analysis Identifies PLK1 Crucial for the Tumorigenesis of Clear Cell Renal Cell Carcinoma

open access: yesJournal of Inflammation Research, 2022
Yiguan Qian,* Yang Li,* Ke Chen,* Ning Liu, Xi Hong, Di Wu, Zheng Xu, Liuhua Zhou, Luwei Xu, Ruipeng Jia, Yu-Zheng Ge Department of Urology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China&ast ...
Qian Y   +10 more
doaj  

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