Sunitinib treatment for patients with clear-cell metastatic renal cell carcinoma: clinical outcomes and plasma angiogenesis markers [PDF]
Loukas Kontovinis+5 more
openalex +1 more source
This study developed an unsupervised radiomics system integrating CT imaging and multi‐omics data to stratify clear cell renal cell carcinoma into two subtypes with distinct clinical outcomes. Cluster 1 showed lower recurrence risk and active immunity, while Cluster 2 exhibited higher recurrence risk, enriched VHL/KDM5C mutations, immunosuppressive ...
Yusheng Guo+14 more
wiley +1 more source
Molecular Mechanisms of Drug Resistance in Clear Cell Renal Cell Carcinoma. [PDF]
Bianchi N, Ancona P, Aguiari G.
europepmc +1 more source
Systematic Comparative Protein Expression Profiling of Clear Cell Renal Cell Carcinoma [PDF]
Rudolf Lichtenfels+10 more
openalex +1 more source
SGCD presents a novel approach for tissue spatial domain identification by employing interpolation to estimate inter‐spot gene expression and deconvolution to resolve cell‐type composition in both sampled and interstitial regions. By integrating gene expression, cell type, and spatial coordinates within a graph contrastive learning framework, SGCD ...
Tianjiao Zhang+7 more
wiley +1 more source
Deletion of the transcription factor ATF4 in a model of clear cell renal cell carcinoma. [PDF]
Chi Y+6 more
europepmc +1 more source
Is there any potential link among caspase-8, p-p38 MAPK and bcl-2 in clear cell renal cell carcinomas? A comparative immunohistochemical analysis with clinical connotations [PDF]
Vassilis Samaras+7 more
openalex +1 more source
A Network‐Driven Framework for Drug Response Precision Prediction of Acute Myeloid Leukemia
A network‐based precision medicine platform, named NetAML is offered for personalized treatment of AML. It combines network analysis and machine learning to develop 87 models predicting drug sensitivity for clinical drugs. NetAML identifies interpretable gene signatures that drive differential drug responses, enabling the prediction of individual ...
Yinyin Wang+7 more
wiley +1 more source
Recent progress in non-clear cell renal cell carcinoma: biology and therapeutic strategies. [PDF]
Yildirim A+6 more
europepmc +1 more source
Possible role of the RhoC/ROCK pathway in progression of clear cell renal cell carcinoma
Hideyuki Abe+11 more
openalex +2 more sources