Results 81 to 90 of about 367,353 (219)

Decoding the multicellular ecosystem of vena caval tumor thrombus in clear cell renal cell carcinoma by single-cell RNA sequencing

Genome Biology, 2022
Background Vascular invasion with tumor thrombus frequently occurs in advanced renal cell carcinoma (RCC). Thrombectomy is one of the most challenging surgeries with high rate of perioperative morbidity and mortality.
Yue Shi, Qi Zhang, H. Bi, Minqiang Lu, Ye-Hui Tan, D. Zou, L. Ge, Zhigang Chen, Cheng Liu, W. Ci, Lulin Ma   +10 more
semanticscholar   +1 more source

Leveraging diverse cell-death related signature predicts the prognosis and immunotherapy response in renal clear cell carcinoma

Frontiers in Immunology, 2023
BackgroundModulation of programmed cell death in tumor cells alters the tumor microenvironment and the influx of tumor-infiltrating lymphocytes, and the combination of its inducers and immune checkpoint inhibitors plays a synergistic role in enhancing ...
Zhengqi Wu, Mingyue Jin, Peng Xin, Hao Zhang   +3 more
doaj   +1 more source

Integrative Analysis of Histopathological Images and Genomic Data Predicts Clear Cell Renal Cell Carcinoma Prognosis [PDF]

, 2017
In cancer, both histopathologic images and genomic signatures are used for diagnosis, prognosis, and subtyping. However, combining histopathologic images with genomic data for predicting prognosis, as well as the relationships between them, has rarely ...
Cheng, Jun, Feng, Qianjin, Han, Yatong, Han, Zhi, Huang, Kun, Meng, Yuebo, Parwani, Anil, Wang, Xusheng, Ye, Xiufen, Zhang, Jie   +9 more
core   +1 more source

Multi-omic profiling of clear cell renal cell carcinoma identifies metabolic reprogramming associated with disease progression

Nature Genetics
Clear cell renal cell carcinoma (ccRCC) is a complex disease with remarkable immune and metabolic heterogeneity. Here we perform genomic, transcriptomic, proteomic, metabolomic and spatial transcriptomic and metabolomic analyses on 100 patients with ...
Junyi Hu, Shaogang Wang, Yaxin Hou, Zhaohui Chen, Lilong Liu, Ruizhi Li, Nisha Li, Lijie Zhou, Yu Yang, Liping Wang, Liang Wang, Xiong Yang, Yichen Lei, Changqi Deng, Yang Li, Zhiyao Deng, Yuhong Ding, Yingchun Kuang, Zhipeng Yao, Yang Xun, Fan Li, Heng Li, J. Hu, Zhenghao Liu, Tao Wang, Yi Hao, X. Jiao, W. Guan, Z. Tao, Shancheng Ren, Ke Chen   +30 more
semanticscholar   +1 more source

LncRNA HCG18 Promotes Clear Cell Renal Cell Carcinoma Progression by Targeting miR-152-3p to Upregulate RAB14

Cancer Management and Research, 2021
Yu Yang,1 Pengfeng Gong,2 Dongwei Yao,3 Dong Xue,2 Xiaozhou He2 1Department of Hepatopancreatobiliary Surgery, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, People’s Republic of China; 2Department of Urology, The Third ...
Yang Y, Gong P, Yao D, Xue D, He X
doaj  

FOXD1 regulates cell division in clear cell renal cell carcinoma

BMC Cancer, 2021
Background Forkhead transcription factors control cell growth in multiple cancer types. Foxd1 is essential for kidney development and mitochondrial metabolism, but its significance in renal cell carcinoma (ccRCC) has not been reported.
Kyle H. Bond, Jennifer L. Fetting, Christine W. Lary, Ivette F. Emery, Leif Oxburgh   +4 more
doaj   +1 more source

腎細胞癌の膵転移の1例 [PDF]

, 1990
A case of asynchronous bilateral renal cell carcinoma with pancreatic metastasis is described. Left nephrectomy and tumorectomy in the right kidney were performed.
Gohji, Kazuo, Kamidono, Sadao, Matsumoto, Osamu   +2 more
core  

Renal cell carcinoma: a nomogram for the CT imaging-inclusive prediction of indolent, non-clear cell renal cortical tumours [PDF]

, 2016
Aim To develop a nomogram from clinical and computed tomography (CT) data for pre-treatment identification of indolent renal cortical tumours. Patients and methods A total of 1201 consecutive patients underwent dedicated contrast-enhanced CT prior to ...
Asnis-Alibozek, Cardone, Hindman, Karlo, Karlo, Karlo, Kim, Kovacs, Lane, Lowrance, Moch, Raj, Sasiwimonphan, Truong, Vargas, Young   +15 more
core   +1 more source

[89Zr]Zr-girentuximab for PET-CT imaging of clear-cell renal cell carcinoma: a prospective, open-label, multicentre, phase 3 trial.

The Lancet Oncology
BACKGROUND With limitations of conventional imaging and biopsy, accurate, non-invasive techniques to detect clear-cell renal cell carcinoma in patients with renal masses remain an unmet need.
B. Shuch, A. Pantuck, Jean-Christophe Bernhard, Michael A. Morris, Viraj A. Master, A. Scott, Charles van Praet, Clement Bailly, Bülent Önal, Tamer Aksoy, R. Merkx, David M. Schuster, Sze Ting Lee, N. Pandit-Taskar, Alice C. Fan, Phillip Allman, Karl Schmidt, L. Tauchmanova, M. Wheatcroft, Christian Behrenbruch, Colin Hayward, Peter Mulders   +21 more
semanticscholar   +1 more source

Clinicopathological profile of clear cell renal cell carcinoma

International Journal of Health and Medical Sciences, 2022
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer with aggressive behavior. Tumor stage and grade are important parameter in diagnosis.
Pamela Kusumadewi Putri Thaib, A. S. Rahaju   +1 more
semanticscholar   +1 more source