Results 71 to 80 of about 619,956 (264)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Hacking Experiment Using USB Rubber Ducky Scripting [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2017
By leaving your computer unlocked while you are away for seconds can give hackers all the time they need to obtain your personal information from your computer. This paper aims to detail the necessary research and development of a USB Rubber Ducky script,
Benjamin Cannoles, Ahmad Ghafarian
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

Pass-back chain extension expands multimodular assembly line biosynthesis. [PDF]

open access: yes, 2020
Modular nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) enzymatic assembly lines are large and dynamic protein machines that generally effect a linear sequence of catalytic cycles.
Huan, Tao   +5 more
core  

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

Explaining Levels of Customer Satisfaction with First Contact with Jobcentre Plus: results of qualitative research with Jobcentre Plus Staff [PDF]

open access: yes, 2009
This report is a follow up to the First Contact Customer Survey (Research Report 504). As a result of ongoing difficulties accessing data for sampling purposes, the initial plan to undertake qualitative follow-up research with customers was abandoned in ...
Bickerstaffe, T, Nunn, A, Wymer, P
core  

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

"Stone Sutras" of Xinjiang

open access: yesOriental Studies, 2018
The article presents a data of the “stone sutras” which are an integral part of the written and spiritual heritage of the Oirats. The description of the texts on “Clear Script” which were found out on six stones in one of residing areas of Xinjiang ...
Do. Batujav
doaj  

A Study on the Irrational Proportion in the Structure of Thuluth Scripts [PDF]

open access: yesهنر اسلامی, 2015
Undoubtedly, one of the influential ways of assessing art works qualities is to examine its geometrical order and proportions. Also, the existence of golden proportion criterion and mathematical and geometrical proportion in the world as well as the ...
Hamid reza chatr Bahr   +2 more
doaj  

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