Results 51 to 60 of about 619,956 (264)

‘The Story of Usun Debeskertu Khan’: Didactic Essentials

open access: yesМонголоведение, 2019
The Story of Usun Debeskertu Khan is a most famous Oirat (Kalmyk) Clear Script literary composition. The text consists of homilies delivered by Tibetan King Tri Palpachen and his sixteen senior executives.
Baazr A. Bicheev
doaj   +1 more source

Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. [PDF]

open access: yes, 2009
The innate immune response of airway epithelial cells to airborne allergens initiates the development of T cell responses that are central to allergic inflammation.
Angkasekwinai, Pornpimon   +14 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Pragmatic Functions of Repetition in TV Discourse [PDF]

open access: yes, 2012
Since repetition is a natural phenomenon used to perform various functions in interactional discourse, adopting a pragmatic analysis to the discourse of Dr. Phil and his guests on Dr.
Abuseileek Ali Farhan, Rabab'ah Ghaleb
core   +2 more sources

Christian improvisation

open access: yesScandinavian Journal for Leadership & Theology, 2023
My thesis in this article is that Christian improvisation is a helpful way to understand the practice of Christian leadership ethics. We sometimes find ourselves in ethical situations with no clear script or guideline to prescribe actions. In such cases,
Martin Jakobsen
doaj   +1 more source

Psychodynamic therapy: a poorly defined concept with questionable evidence [PDF]

open access: yes, 2016
R34 MH086668 - NIMH NIH HHS; R01 AT007257 - NCCIH NIH HHS; R21 MH101567 - NIMH NIH HHS; R34 MH099311 - NIMH NIH HHS; R21 MH102646 - NIMH NIH HHS; K23 MH100259 - NIMH NIH HHS; R01 MH099021 - NIMH NIH ...
Hofmann, Stefan G.
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Sul cambiamento di stile nella scrittura onciale

open access: yesAnnali Online dell'Università di Ferrara. Sezione Lettere, 2015
This work aim to explain the developments, still not so clear, that led to the transition from the so-called uncial old-style to an uncial new-style. Trought an attentive paleografical analysis the author tries to inquire not only times and causes, but ...
Roberta Iannetti
doaj   +1 more source

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