Results 131 to 140 of about 1,368,548 (310)

Records of the Diurnal Variations of the Quantity and Quality of Water in the Clear Creek Basin, Texas, February 14-17, 1972 [PDF]

open access: yes, 1972
36 pages; available for download at the link below.Periodically since May 1971, the US Geological Survey, in cooperation with the Texas Water Quality Board and Texas Water Development Board, has measured the discharge and determined the water quality at ...
Fisher, J. C.   +2 more
core   +2 more sources

Synthesis, Characterization, and Toxicity Evaluation of Size-Dependent Iron-Based Metal–Organic Frameworks

open access: yesNanomaterials
Iron-based metal–organic frameworks (Fe-MOFs) are promising for biomedical and environmental applications due to their porosity, tunable chemistry, and biocompatibility. This study examines how particle size, morphology, and ligand composition affect the
Zhang Liu   +7 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Staff report -- the Clear Creek/Clear Lake Basin and the Clear Lake board order [PDF]

open access: yes, 1980
45 p.No abstract availablehttp://gbic.tamug.edu/request ...
Texas Department of Water Resources
core  

Metasurface for programmable quantum algorithms with classical and quantum light

open access: yesNanophotonics
Metasurfaces have recently opened up applications in the quantum regime, including quantum tomography and the generation of quantum entangled states. With their capability to store a vast amount of information by utilizing the various geometric degrees ...
Tanuwijaya Randy Stefan   +6 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

A report on a water quality survey Stony Lake and Clear Lake in the County of Peterborough [PDF]

open access: yes, 1969
A survey was performed on August 14 and September 11, 1969, to assess the water quality of Stony Lake and adjoining Clear ...
Division of Sanitary Engineering, District Engineers Branch, Ontario Water Resources Commission
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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