Results 221 to 230 of about 928,462 (307)

Time-varying voriconazole clearance during extracorporeal membrane oxygenation. [PDF]

Antimicrob Agents Chemother
Yusuff H, Gadsby J, Isgro G, Zochios V, Jenkins D, Cooke S, Mulla H.   +6 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

CLEARANCE: Apple MacBook-Air $36.90

, 2015
LG-Holiday-Clearance
core  

Sustained HBsAg clearance induced by pegylated interferon α-2b in HBeAg-negative patients with low baseline HBsAg. [PDF]

Front Cell Infect Microbiol
Wen C, He T, Zha G, Li A, Wang Z, Zhou Z, Cai D, Zhang D, Peng M, Shi X, Ren H.   +10 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Physiological brain clearance architecture revealed by neuronal protein tracing. [PDF]

Cell
Chayama Y, Rao NR, Perla D, Zhang Z, Reid M, Nelson S, Wen X, Ding B, Blumenfeld J, Apolonio A, Doddipalli S, Zhou H, Turhan SG, Shih PY, Brendel M, Fu YH, Ertürk A, Kolabas ZI, Huang Y, Yang AC.   +19 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

CLEARANCE: Apple MacBook-Air $36.90, Expires 10.31.2015

, 2015
Beats Black Friday Clearance
core  

Transient Interferon-Driven Natural Killer Cell Activation in Acute Hepatitis C. [PDF]

J Infect Dis
Strunz B, Zhan Q, Khera T, Hengst J, Jankovic M, Deterding K, Niehrs A, Cornberg M, Xu CJ, Wedemeyer H, Björkström NK, HepNet Acute HCV IV Study Group .   +11 more
europepmc   +1 more source