Continuous Subcutaneous Ketamine Infusion May Induce Tacrolimus and Sirolimus Clearance: A Case Report. [PDF]
Stojanova J +9 more
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Phase Segmentation and Phase-Specific Kinematic Feature Extraction of Hurdle Clearance Based on Monocular Video and Markerless Pose Estimation. [PDF]
Guo Y, Zheng S, Liu C, Li H.
europepmc +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Effect of Semi-sitting Position on Airway Clearance Obtained by Jaw Thrust During Oral Fiberoptic-Guided Intubation. [PDF]
Saurabh K, Shami Y.
europepmc +1 more source
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Correction to: The long walk to a short half-life: the discovery of augmented renal clearance and its impact on antibiotic dosing. [PDF]
europepmc +1 more source
Impact of analysis of risk factors for residual stones after flexible ureteroscopic lithotripsy in patients with upper urinary tract stones. [PDF]
Fan D, Li Y, Gao Z, Han Y.
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Fading the spots: a pilot case series of partial unilateral lentiginosis treated with Q-switched Nd: YAG laser. [PDF]
Jindal A, Bansal K, Wadhwa A, Goel S.
europepmc +1 more source

