Results 231 to 240 of about 1,663,252 (327)

Strategies Utilized while Minimizing Ankle Motion Bilaterally and Unilaterally during Level Ground Walking and Obstacle Clearance Tasks

, 2010
Eoghan Landy
openalex   +1 more source

Degradation and clearance of atrial natriuretic factors [PDF]

, 1990
Adnot, Almeida, Anand-Srivastava, Anand-Srivastava, Anderson, Ando, Arendt, Arendt, Ballermann, Ballermann, Bates, Bertrand, Bianchi, Bianchi, Cachofeiro, Cantin, Cantin, Chartier, Chinkers, Cody, Crozier, De Bold, De Lean, Drexler, Espiner, Fethiere, Fulcher, Gerbes, Gerbes, Gerbes, Gines, Gros, Gutkowska, Hasegawa, Henriksen, Hinko, Hollister, Inagami, Kenny, Koehn, Koepke, Kollenda, Koseki, Krieter, Kurosawa, Lafferty, Laffi, Lang, Lang, Laragh, Leitman, Lieorens, Luft, Maack, Mantyh, Marumo, Masuda, Matsas, Matsas, Matsas, Misono, Murthy, Nakao, Needleman, Northridge, Olins, Olins, Olins, Pandey, Porter, Predel, Raine, Richards, Riegger, Saito, Scarborough, Schafferhans, Schiebinger, Schutten, Schwartz, Seymour, Shima, Sonnenberg, Stephenson, Stewart, Sudhir, Sugiyama, Sybertz, Sybertz, Takayanagi, Tamburini, Tang, Thibault, Trapani, Trapani, Trippodo, Vierhapper, Vollmar, Vollmar, Vollmar, Webb, Woods, Yukimura   +102 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Population pharmacokinetics of imipenem in different populations for individualized dosing: a systematic review. [PDF]

Front Pharmacol
Zhang P, Zhao Y, Zhu J, Yang Y, Liang G, Wang X, Yu Z.   +6 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Western pediatric cervical spine study: an observational prospective Western Pediatric Surgery Research Consortium and Western Trauma Association multicenter study protocol. [PDF]

Trauma Surg Acute Care Open
Eldredge RS, Kahan AM, Padilla BE, Patwardhan UM, Presson AP, Larsen K, Lee JH, Ostlie DJ, Jensen AR, Melhado CG, Ignacio RC, Chao SD, Ravindra VM, Swendiman R, Iyer RR, Brockmeyer DL, Kelley-Quon LI, Escobar MA, Yorkgitis BK, Inaba K, Russell KW.   +20 more
europepmc   +1 more source

Lung Clearance Index in Adults and Children With Cystic Fibrosis

, 2016
Katherine O’Neill, Michael M. Tunney, E. Johnston, Stephen Rowan, D.G. Downey, Jacqueline C. Rendall, Alastair Reid, Ian Bradbury, J.S. Elborn, Judy Bradley   +9 more
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Enhanced Clearance of HIV-1 Broadly Neutralizing Antibody VRC07-523-LS During Viremia: Influences on Trial Design and Analysis. [PDF]

Clin Transl Sci
Smith NM, Ho BM, Bar KJ, Gama L, Dziubla G, Koup RA, Pensiero M, Serebryannyy L, Caskey M, Wilkin TJ, Wood TD, Morse GD, Venuto CS, Cha R, Ma Q.   +14 more
europepmc   +1 more source