Results 31 to 40 of about 1,602,450 (278)

Astrocytic LRP1 mediates brain Aβ clearance and impacts amyloid deposition [PDF]

, 2017
Accumulation and deposition of amyloid-β (Aβ) in the brain represent an early and perhaps necessary step in the pathogenesis of Alzheimer's disease (AD).
Bu, Guojun, Cirrito, John R, Holtzman, David M, Hu, Jin, Kanekiyo, Takahisa, Liu, Chia-Chen, Na, Wang, Wang, Jian, Zhao, Na   +8 more
core   +2 more sources

Effect of Acute Thermal Stress Exposure on Ecophysiological Traits of the Mediterranean Sponge Chondrilla nucula: Implications for Climate Change

Biology, 2023
As a result of climate change, the Mediterranean Sea has been exposed to an increase in the frequency and intensity of marine heat waves in the last decades, some of which caused mass mortality events of benthic invertebrates, including sponges.
Mar Bosch-Belmar, Martina Milanese, Antonio Sarà, Valeria Mobilia, Gianluca Sarà   +4 more
doaj   +1 more source

Delayed Clearance of Viral RNA in Sputum for Severity COVID-19 Patients with Initial High Viral Load

Infection and Drug Resistance, 2022
Hong Zhao,* Huilan Tu,* Xia Yu,* Junwei Su, Xuan Zhang, Kaijin Xu, Yu Shi, Yunqing Qiu, Jifang Sheng State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National ...
Zhao H, Tu H, Yu X, Su J, Zhang X, Xu K, Shi Y, Qiu Y, Sheng J   +8 more
doaj  

The effect of a multidisciplinary weight loss program on renal circadian rhythm in obese adolescents

, 2019
Adolescent obesity is a serious health problem associated with many comorbidities. Obesity-related alterations in circadian rhythm have been described for nocturnal blood pressure and for metabolic functions.
Bruneel, Elke, De Guchtenaere, Ann, Dejonckheere, Sarah, Everaert, Karel, Keersmaekers, Laura, Pauwaert, Kim, Roggeman, Saskia, Van der Jeugt, Jolien, Vande Walle, Johan   +8 more
core   +1 more source

What you see is what you step: the horizontal-vertical illusion increases toe clearance in older adults during stair ascent [PDF]

, 2015
PURPOSE Falls on stairs are a significant cause of morbidity and mortality in elderly people. A simple safety strategy to avoid tripping on stairs is increasing foot clearance. We determined whether a horizontal–vertical illusion superimposed onto stairs
Buckley, JG, Elliott, DB, Foster, RJ, Scally, AJ, Whitaker, D   +4 more
core   +1 more source

Challenges and roadblocks to robust metadata in the scholarly communications industry

Insights: The UKSG Journal
For the scholarly communications community to extract the most value from scientific research, as well as to successfully move from subscription to open access publishing models, it is essential to have ‘clean’ metadata and a robust infrastructure to ...
Deni Auclair, Jamie Carmichael, Jessica Thibodeau   +2 more
doaj   +1 more source

Sultiame pharmacokinetic profile in plasma and erythrocytes after single oral doses: A pilot study in healthy volunteers

Pharmacology Research & Perspectives, 2020
A pilot study was conducted aiming at specifying sultiame's pharmacokinetic profile, completed by in vitro assays evaluating the intraerythrocytic transfer of sultiame and by a pharmacokinetic model assessing its distribution.
Kim Dao, Paul Thoueille, Laurent A. Decosterd, Thomas Mercier, Monia Guidi, Carine Bardinet, Sébastien Lebon, Eva Choong, Arnaud Castang, Catherine Guittet, Luc‐André Granier, Thierry Buclin   +11 more
doaj   +1 more source

Non-destructive technique to verify clearance of pipes [PDF]

Nuclear Technology and Radiation Protection, 2010
A semi-empirical, non-destructive technique to evaluate the activity of gamma ray emitters in contaminated pipes is discussed. The technique is based on in-situ measurements by a portable NaI gamma ray spectrometer.
Savidou Anastasia, Stamatelatos Ion E.
doaj   +1 more source

Effects of bearing clearance on the chatter stability of milling process [PDF]

, 2010
In the present study, the influences of the bearing clearance, which is a common fault for machines, to the chatter stability of milling process are examined by using numerical simulation method.
Altintas, Altintas, Balachandran, Boothroyd, Clancy, Fofana, Fofana, G. Meng, Ganesan, Gao, Gupta, Inasaki, Insperger, Jeffreys, Karpenko, Kim, Kline, Koenigsberger, L.Z. Guo, Li, Litak, M.R. Jackson, Moon, Opitz, R.M. Parkin, Rivin, Stépán, Tian, Tobias, Wiercigroch, Wiercigroch, Z.K. Peng, Zheng   +32 more
core   +1 more source

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source