Results 41 to 50 of about 1,545,869 (342)

The value of statistical life and cost–benefit evaluations of landmine clearance in Cambodia [PDF]

open access: yes, 2010
Development agencies spend approximately US$ 400 million per year on landmine clearance. Yet many cost–benefit evaluations suggest that landmine clearance is socially wasteful because costs appear to far outweigh social benefits.
Cameron, Michael Patrick   +5 more
core   +2 more sources

Influence of Aerodynamic Preloads and Clearance on the Dynamic Performance and Stability Characteristic of the Bump-Type Foil Air Bearing

open access: yesMachines, 2021
The dry lubricated bump-type foil air bearing enables a carrying load capacity due to a pressure build up in a convergent air film. Since the air bearing provides low power dissipation above the lift-off speed and the flexible foil provides an adaptivity
Fabian Walter, Michael Sinapius
doaj   +1 more source

Challenges and roadblocks to robust metadata in the scholarly communications industry

open access: yesInsights: The UKSG Journal
For the scholarly communications community to extract the most value from scientific research, as well as to successfully move from subscription to open access publishing models, it is essential to have ‘clean’ metadata and a robust infrastructure to ...
Deni Auclair   +2 more
doaj   +1 more source

ADMA metabolism and clearance [PDF]

open access: yesVascular Medicine, 2005
The plasma concentration of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, is the resultant of many processes at cellular and organ levels. Post-translational methylation of arginine residues of proteins plays a crucial role in the regulation of their functions, which include processes such as transcription ...
openaire   +4 more sources

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome [PDF]

open access: yes, 2009
Expansion of the polyglutamine repeat within the protein Huntingtin (Htt) causes Huntington's disease, a neurodegenerative disease associated with aging and the accumulation of mutant Htt in diseased neurons.
Aiken   +97 more
core   +3 more sources

Relevance of In Vitro Metabolism Models to PET Radiotracer Development: Prediction of In Vivo Clearance in Rats from Microsomal Stability Data

open access: yesPharmaceuticals, 2019
The prediction of in vivo clearance from in vitro metabolism models such as liver microsomes is an established procedure in drug discovery. The potentials and limitations of this approach have been extensively evaluated in the pharmaceutical sector ...
Daniela Schneider   +5 more
doaj   +1 more source

The renal clearance and infusion clearance of inulin are similar, but not identical

open access: yesKidney International, 1993
Thirty-eight simultaneous renal (R-Cin) and infusion (INF-Cin) clearances of inulin were done. The equilibration period preceding the clearance studies was of at least two hours duration. The R-Cin on each subject was based on two clearance periods during which the plasma inulin concentration ([P(in)]) varied by 1.0 mg/dl or less and the rate of inulin
Bradley A. Warady   +3 more
openaire   +3 more sources

Factors associated with spontaneous clearance of chronic hepatitis C virus infection [PDF]

open access: yes, 2016
Background & Aims: Spontaneous clearance of chronic hepatitis C virus (HCV) infection (CHC) is rare. We conducted a retrospective case-control study to identify rates and factors associated with spontaneous clearance of CHC.
Aitken, Celia   +11 more
core   +2 more sources

Effect of Acute Thermal Stress Exposure on Ecophysiological Traits of the Mediterranean Sponge Chondrilla nucula: Implications for Climate Change

open access: yesBiology, 2023
As a result of climate change, the Mediterranean Sea has been exposed to an increase in the frequency and intensity of marine heat waves in the last decades, some of which caused mass mortality events of benthic invertebrates, including sponges.
Mar Bosch-Belmar   +4 more
doaj   +1 more source

The effect of a multidisciplinary weight loss program on renal circadian rhythm in obese adolescents

open access: yes, 2019
Adolescent obesity is a serious health problem associated with many comorbidities. Obesity-related alterations in circadian rhythm have been described for nocturnal blood pressure and for metabolic functions.
Bruneel, Elke   +8 more
core   +1 more source

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