Results 51 to 60 of about 782,486 (258)

Phospholipids: Key Players in Apoptosis and Immune Regulation

Molecules, 2009
Phosphatidylserine (PS), a phospholipid predominantly found in the inner leaflet of eukaryotic cellular membranes, plays important roles in many biological processes.
Udo S. Gaipl, Martin Herrmann, Benjamin Frey, Christina Janko, Luis E. Muñoz, Ricardo A. Chaurio   +5 more
doaj   +1 more source

Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel, Santiago Pérez‐Hoyos, Aroa Soriano, Ana Coma, Amalia Varo, Raquel Hladun, Gabriela Guillén, Soraya Mico, Marta Garrido, Lourdes Rubio, Alba Rubio‐San‐Simón, Ana Minguez, Ricardo López‐Almaraz, Laura Illade, Miguel F. Segura, Lucas Moreno   +15 more
wiley   +1 more source

Phenotyping of CYP3A by Oral Midazolam in Healthy Mazandarani Volunteers (Iran)

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2011
BACKGROUND AND OBJECTIVE: CYP3A is responsible for hepatic microsomal metabolism of more than 50% of drugs which are its specific substrate. Metabolic activity of this enzyme depends on several factors.
MR Shiran, S , Gharooee Ahangar, SH Rostamkolaee, AA Sefidgar, M Baradaran, M Hashemi, M Baleghi, AA Moghadamnia   +7 more
doaj  

Inpatient Exposure, Confidence, and Knowledge in Pediatric Hematology/Oncology: Evaluating General Pediatric Residents During 2025 ACGME Curriculum Change

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background General pediatricians often evaluate hematologic and oncologic presentations before subspecialty consultation, yet the 2025 Accreditation Council for Graduate Medical Education (ACGME) pediatric requirements reduce inpatient pediatric hematology/oncology (PHO) time, raising questions about resident readiness.
Colburn Yu, Rohini Jain
wiley   +1 more source

The potential of bacterial anti-phagocytic proteins in suppressing the clearance of extracellular vesicles mediated by host phagocytosis

Frontiers in Immunology
Extracellular vesicles (EVs), characterized by low immunogenicity, high biocompatibility and targeting specificity along with excellent blood-brain barrier permeability, are increasingly recognized as promising drug delivery vehicles for treating a ...
Jiacong Sun, Congcong Chen, Pengpeng Pan, Keyi Zhang, Jinrui Xu, Jinrui Xu, Cheng Chen   +6 more
doaj   +1 more source

Determination of Tangeretin in Rat Plasma: Assessment of Its Clearance and Absolute Oral Bioavailability

Pharmaceutics, 2017
Tangeretin (TAN) is a dietary polymethoxylated flavone that possesses a broad scope of pharmacological activities. A simple high-performance liquid chromatography (HPLC) method was developed and validated in this study to quantify TAN in plasma of ...
Mai Gamal Elhennawy, Hai-Shu Lin
doaj   +1 more source

Consensus Standards and Recommendations for Developmental and Cognitive Surveillance, Screening, and Evaluation in Sickle Cell Disease: Executive Summary From the National Alliance of Sickle Cell Centers Neurocognitive Workgroup

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurodevelopmental and neurocognitive difficulties are prevalent among individuals with sickle cell disease and warrant prompt identification and support. This Special Report provides an executive summary of standards and recommendations for surveillance, screening, and evaluation for development and cognition across the lifespan developed by ...
Alyssa M. Schlenz, Donna Murdaugh, Andrew M. Heitzer, Jennifer N. Longoria, Wendy Santos‐Modesitt, Arianna Martin, Judy Cavazos, Jeff Schatz, Catherine R. Hoyt, Alison King, Eboni I. Lance, Steven Hardy, Marsha Treadwell   +12 more
wiley   +1 more source

Vibro-Impact Energy Analysis of a Geared System with Piecewise-Type Nonlinearities Using Various Parameter Values

Energies, 2015
Torsional systems with gear pairs such as the gearbox of wind turbines or vehicle driveline systems inherently show impact phenomena due to clearance-type nonlinearities when the system experiences sinusoidal excitation.
Jong-Yun Yoon, Byeongil Kim
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

The biological role of hemolymph lectins in Episesarma tetragonum

Invertebrate Survival Journal, 2013
The hemolymph of the mangrove crab, E. tetragonum contains lectins specific for NeuGcα 2, 3 Gal β1-4 GluNAc β1 linkage and O-acetyl sialic acids. The role of sialic acid specific lectins on natural immunity of the crab is studied by using several kinds ...
V R Devi, M R Basil-Rose, M D Pallaty
doaj