Results 191 to 200 of about 782,486 (258)

Amyloid-<i>β</i> clearance: an astrocytic perspective. [PDF]

Front Neurosci
Li J, Lv Z, Chen X, Fu F, Yang K, Lai G, Wu H, Xie G.   +7 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

The Influence of Athlete-Specific Factors on Time to Return to Sport Clearance Following Hip Arthroscopy for Femoroacetabular Impingement Syndrome in Division I Collegiate Athletes. [PDF]

Orthop J Sports Med
Kuik ML, Blomquist MB, Knurr KA, Spiker AM.   +3 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Glymphatic-meningeal lymphatic system imbalance: a peripheral-to-central inflammatory bridge in perioperative neurocognitive disorders. [PDF]

Front Immunol
Wang H, Wang X, Liu N, Wang H, Feng C.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Transient Interferon-Driven Natural Killer Cell Activation in Acute Hepatitis C. [PDF]

J Infect Dis
Strunz B, Zhan Q, Khera T, Hengst J, Jankovic M, Deterding K, Niehrs A, Cornberg M, Xu CJ, Wedemeyer H, Björkström NK, HepNet Acute HCV IV Study Group .   +11 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Clinical Management of Antirheumatic Drug Exposure During Therapeutic Plasma Exchange. [PDF]

Clin Rev Allergy Immunol
Ding Z, Li J, Zhong X.
europepmc   +1 more source

The signaling and regulatory functions of dying cells and cell corpses. [PDF]

Commun Biol
Zhang G, Liu J, Li W, Wang B, Feng H, Cui T, Pan T, Chen D, Xiong Y.   +8 more
europepmc   +1 more source