Results 61 to 70 of about 928,462 (307)

Electrolyte-free water clearance versus modified electrolyte-free water clearance: do the results justify the effort?

open access: yes, 2012
Calculation of electrolyte-free water clearance (EFWC) allows for quantification of renal losses of free water and was shown to be helpful in the differential diagnosis of dysnatremias and might help in the correction of the electrolyte disorders.
Lindner, Gregor, Schwarz, Christoph
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Development and Evaluation of Physiologically Based Pharmacokinetic Drug–Disease Models for Predicting Rifampicin Exposure in Tuberculosis and Cirrhosis Populations

open access: yesPharmaceutics, 2019
The physiologically based pharmacokinetic (PBPK) approach facilitates the construction of novel drug−disease models by allowing incorporation of relevant pathophysiological changes.
Muhammad F. Rasool   +7 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Phospholipids: Key Players in Apoptosis and Immune Regulation

open access: yesMolecules, 2009
Phosphatidylserine (PS), a phospholipid predominantly found in the inner leaflet of eukaryotic cellular membranes, plays important roles in many biological processes.
Udo S. Gaipl   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Non-Uniform Clearance between Rotor Surfaces and Its Effect on Machine Performance in Twin-Screw Compressors

open access: yes, 2012
The performance of twin-screw compressors is primarily affected by the clearance between a pair of meshing rotors. This study proposes a method for calculating the normal clearance along the contact line between rotors using two normal rack curves, which
Wu, Yu-Ren   +2 more
core   +1 more source

Numerical error evaluation for tip clearance flow calculations in a centrifugal compressor [PDF]

open access: yes, 2004
Since globally mesh independent solution are still beyond available computer resources for industrial cases, a method to quantify locally the numerical error is proposed. The design of experiments method helps selecting mesh parameters that influence the
Dufour, Guillaume   +4 more
core  

Current understanding of the mechanisms for clearance of apoptotic cells-a fine balance [PDF]

open access: yes, 2013
Apoptosis is an important cell death mechanism by which multicellular organisms remove unwanted cells. It culminates in a rapid, controlled removal of cell corpses by neighboring or recruited viable cells.
Andrew Devitt   +3 more
core   +1 more source

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