Results 241 to 250 of about 73,235 (301)

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

A theoretical exploration of protocols for treating prosthetic joint infections with combinations of antibiotics and bacteriophage. [PDF]

NPJ Biofilms Microbiomes
Levin BR, Gil-Gil T, Berryhill BA, Woodworth MH.   +3 more
europepmc   +1 more source

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

Advanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter, Abigail R. Fabiano, Ehsan Aalaei, Jason Deng, Dakota E. Rostant, Michael R. King   +5 more
wiley   +1 more source

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

Mitochondrial-targeted therapy for osteoarthritis: Challenges and opportunities from basic research to clinical translation. [PDF]

Front Immunol
Zhang SO, Gu ZQ, Ruan J, Zhang J, Chen H.   +4 more
europepmc   +1 more source

A Mouse-Adapted CHIKV Strain Harboring E2-K200R and Non-Structural Mutations Exhibits Enhanced Pathogenicity in Multiple Rodent Models. [PDF]

Viruses
Tang C, Li B, Huang Q, Yang Y, Yu W, Zhou Y, Wu D, Yang H, Wang H, Wang J, Lu S.   +10 more
europepmc   +1 more source

Nanocarrier-based delivery of siRNA therapeutics in rheumatoid arthritis: immune mechanisms and translational perspectives. [PDF]

Front Immunol
Bai L, Su P.
europepmc   +1 more source

Impaired Macrophage Efferocytosis: Shared Mechanisms and Therapeutic Implications in Immune-Mediated Inflammatory Diseases. [PDF]

J Inflamm Res
He Z, Chen N, Zhang Y, Du H, Jie L.
europepmc   +1 more source

Impact of Nintendo Ring Fit exergaming on lower-limb asymmetry and joint angles in women with chronic nonspecific low back pain during obstacle crossing. [PDF]

BMC Sports Sci Med Rehabil
Wang IL, Lu FF, Chiu CH, Su Y, Tao H, Lai CY.   +5 more
europepmc   +1 more source

IgA nephropathy with rheumatoid arthritis related to adalimumab. [PDF]

CEN Case Rep
Tüfekçi B, Kardaş RC, Öğüt B, Erden A.   +3 more
europepmc   +1 more source