Results 11 to 20 of about 22,447 (214)

Comprehensive assessment of cleavage and polyadenylation specificity factors in hepatocellular carcinoma: Expression, prognostic significance and immune infiltration analysis. [PDF]

Mol Clin Oncol
Lu Y, Wang T, Yan X, Zhang H.
europepmc   +2 more sources

HIV-1 capsid-targeting domain of cleavage and polyadenylation specificity factor 6. [PDF]

J Virol, 2012
Lee K, Mulky A, Yuen W, Martin TD, Meyerson NR, Choi L, Yu H, Sawyer SL, Kewalramani VN.   +8 more
europepmc   +3 more sources

The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes. [PDF]

J Biol Chem, 2016
Rasheedi S, Shun MC, Serrao E, Sowd GA, Qian J, Hao C, Dasgupta T, Engelman AN, Skowronski J.   +8 more
europepmc   +3 more sources

CPSF4-mediated regulation of alternative splicing of HMG20B facilitates the progression of triple-negative breast cancer [PDF]

Journal of Translational Medicine
Background Aberrant alternative splicing (AS) contributes to tumor progression. A crucial component of AS is cleavage and polyadenylation specificity factor 4 (CPSF4).
Guansheng Zhong, Qinyan Shen, Xinli Zheng, Kun Yu, Hongjiang Lu, Bajin Wei, Haidong Cui, Zhijun Dai, Weiyang Lou   +8 more
doaj   +2 more sources

Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6. [PDF]

RNA, 2013
Evsyukova I, Bradrick SS, Gregory SG, Garcia-Blanco MA.   +3 more
europepmc   +3 more sources

Molecular details of the CPSF73-CPSF100 C-terminal heterodimer and interaction with Symplekin

Open Biology, 2023
Eukaryotic pre-mRNA is processed by a large multiprotein complex to accurately cleave the 3′ end, and to catalyse the addition of the poly(A) tail.
Stéphane Thore, Finaritra Raoelijaona, Vincent Talenton, Sébastien Fribourg, Cameron D. Mackereth   +4 more
doaj   +1 more source

Darstellung und Charakterisierung der humanen 3‘-Prozessierungsfaktoren mPSF und CF II [PDF]

, 2021
Reife mRNAs werden in eukaryotischen Zellen in mehreren Schritten aus Vorläufern generiert. Das primäre Transkript wird dabei u.a. durch eine Endonuklease gespalten und danach polyadenyliert.
Schäfer, Peter
core   +1 more source

CAPTURE of the Human U2 snRNA Genes Expands the Repertoire of Associated Factors

Biomolecules, 2022
In order to identify factors involved in transcription of human snRNA genes and 3′ end processing of the transcripts, we have carried out CRISPR affinity purification in situ of regulatory elements (CAPTURE), which is deadCas9-mediated pull-down, of the ...
Joana Guiro, Mathias Fagbemi, Michael Tellier, Justyna Zaborowska, Stephanie Barker, Marjorie Fournier, Shona Murphy   +6 more
doaj   +1 more source

HIV Capsid and Integration Targeting

Viruses, 2021
Integration of retroviral reverse transcripts into the chromosomes of the cells that they infect is required for efficient viral gene expression and the inheritance of viral genomes to daughter cells.
Alan N. Engelman
doaj   +1 more source

Integration of developmental and environmental signals via a polyadenylation factor in Arabidopsis. [PDF]

PLoS ONE, 2014
The ability to integrate environmental and developmental signals with physiological responses is critical for plant survival. How this integration is done, particularly through posttranscriptional control of gene expression, is poorly understood ...
Man Liu, Ruqiang Xu, Carrie Merrill, Liwei Hong, Carol Von Lanken, Arthur G Hunt, Qingshun Q Li   +6 more
doaj   +1 more source