Results 31 to 40 of about 14,699 (328)

Correction: Biphasic targeting and cleavage furrow ingression directed by the tail of a myosin II. [PDF]

J Cell Biol, 2016
Fang X, Luo J, Nishihama R, Wloka C, Dravis C, Travaglia M, Iwase M, Vallen EA, Bi E.   +8 more
europepmc   +2 more sources

Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation.

PLoS Biology, 2009
To complete cell division with high fidelity, cytokinesis must be coordinated with chromosome segregation. Mammalian Polo-like kinase 1, Plk1, may function as a critical link because it is required for chromosome segregation and establishment of the ...
Benjamin A Wolfe, Tohru Takaki, Mark Petronczki, Michael Glotzer   +3 more
doaj   +3 more sources

Targeting Aurora B to the equatorial cortex by MKlp2 is required for cytokinesis. [PDF]

PLoS ONE, 2013
Although Aurora B is important in cleavage furrow ingression and completion during cytokinesis, the mechanism by which kinase activity is targeted to the cleavage furrow and the molecule(s) responsible for this process have remained elusive.
Mayumi Kitagawa, Suet Yin Sarah Fung, Nobuyuki Onishi, Hideyuki Saya, Sang Hyun Lee   +4 more
doaj   +1 more source

Roles of the TRAPP-II Complex and the Exocyst in Membrane Deposition during Fission Yeast Cytokinesis. [PDF]

PLoS Biology, 2016
The cleavage-furrow tip adjacent to the actomyosin contractile ring is believed to be the predominant site for plasma-membrane insertion through exocyst-tethered vesicles during cytokinesis.
Ning Wang, I-Ju Lee, Galen Rask, Jian-Qiu Wu   +3 more
doaj   +1 more source

A nematode kinesin required for cleavage furrow advancement [PDF]

Current Biology, 1998
Dividing cells need to coordinate the separation of chromosomes with the formation of a cleavage plane. There is evidence that microtubule bundles in the interzone region of the anaphase spindle somehow control both the location and the assembly of the cleavage furrow [1-3].
Debra J. Rose, William M. Saxton, Susan Strome, James A. Powers, Olaf Bossinger   +4 more
openaire   +3 more sources

Cytokinesis in bloodstream stage Trypanosoma brucei requires a family of katanins and spastin [PDF]

, 2012
Microtubule severing enzymes regulate microtubule dynamics in a wide range of organisms and are implicated in important cell cycle processes such as mitotic spindle assembly and disassembly, chromosome movement and cytokinesis.
A Baines, A Errico, A Hemphill, A Karabay, A Roll-Mecak, A Roll-Mecak, A Schneider, A Schneider, A Woods, B Lacroix, B Wickstead, C Benz, C Hertz-Fowler, C Lu, C Vedrenne, Caroline Clucas, Corinna Benz, D Buster, D Spitznagel, D Zhang, D Zhang, Dan Zilberstein, DJ LaCount, DR Robinson, E Detmer, E Panteris, E Wirtz, EE Dymek, FJ Ahmad, FJ McNally, FJ McNally, G Burkard, GR Forsythe, H Sudo, H Sudo, H Sudo, HH Lee, HP Price, J Guizetti, J Van den Abbeele, JA Garcia-Salcedo, JA Schiel, JC Munday, JD Diaz-Valencia, Jeremy C. Mottram, JJ Hartman, JJ Hartman, JT Ma, JW Connell, K Gull, K McNally, K Toyo-oka, KJ Evans, KP Mcnally, KP McNally, KP Mcnally, KR Matthews, KY Chan, L Kohl, L Qiang, L Rindisbacher, M Agromayor, M Casanova, M Srayko, MQ Rasi, MR Dow, N Balaban, N Balaban, N Sharma, P Bastin, Q Meng, R Sasse, R Sharma, S Biebinger, S Kelly, S Monnerat, S Olego-Fernandez, S Redmond, S Vaughan, SG Lillico, SH Park, T Sherwin, T Sherwin, T Sherwin, Tansy C. Hammarton, TC Hammarton, TC Hammarton, TC Hammarton, TC Hammarton, W Yu, WQ Yu, Z Li, Z Li   +92 more
core   +9 more sources

Two RhoGEF isoforms with distinct localisation control furrow position during asymmetric cell division

Nature Communications, 2023
Cytokinesis partitions cellular content between daughter cells. It relies on the formation of an acto-myosin contractile ring, whose constriction induces the ingression of the cleavage furrow between the segregated chromatids. Rho1 GTPase and its RhoGEF (
Emilie Montembault, Irène Deduyer, Marie-Charlotte Claverie, Lou Bouit, Nicolas J. Tourasse, Denis Dupuy, Derek McCusker, Anne Royou   +7 more
doaj   +1 more source

A high-resolution shape fitting and simulation demonstrated equatorial cell surface softening during cytokinesis and its promotive role in cytokinesis. [PDF]

PLoS ONE, 2012
Different models for animal cell cytokinesis posit that the stiffness of the equatorial cortex is either increased or decreased relative to the stiffness of the polar cortex.
Hiroshi Koyama, Tamiki Umeda, Kazuyuki Nakamura, Tomoyuki Higuchi, Akatsuki Kimura   +4 more
doaj   +1 more source

LET-99 functions in the astral furrowing pathway, where it is required for myosin enrichment in the contractile ring. [PDF]

, 2017
The anaphase spindle determines the position of the cytokinesis furrow, such that the contractile ring assembles in an equatorial zone between the two spindle poles.
Price, Kari L, Rose, Lesilee S
core   +1 more source

Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells. [PDF]

PLoS Biology, 2009
Animal cells initiate cytokinesis in parallel with anaphase onset, when an actomyosin ring assembles and constricts through localized activation of the small GTPase RhoA, giving rise to a cleavage furrow.
Mark E Burkard, John Maciejowski, Verónica Rodriguez-Bravo, Michael Repka, Drew M Lowery, Karl R Clauser, Chao Zhang, Kevan M Shokat, Steven A Carr, Michael B Yaffe, Prasad V Jallepalli   +10 more
doaj   +1 more source