Results 61 to 70 of about 96,362 (338)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

Comparison of two different secondary rhinoplasties in patients with complete unilateral cleft lip and palate

open access: yesBMC Surgery
Background The purpose of this study was to analysis the nostril symmetry and nasal stability following secondary rhinoplasty performed with either nasal septal cartilage implantation (G1) or simple alar cartilage suspension and internal fixation (G2) in
Shuxia Dong   +7 more
doaj   +1 more source

Clinical profiles of individuals with orofacial clefts: Results from fourteen Eastern African countries.

open access: yesGlobal Pediatrics, 2023
Background: More than 100,000 cleft lip and palate patients have benefited from reconstructive surgeries in Africa because of surgical support from non-governmental organizations such as Smile Train.
Fitsum Kifle Belachew   +5 more
doaj   +1 more source

Retrospective longitudinal analysis of phonetic and phonological cleft palate speech characteristics [PDF]

open access: yes, 2015
In this study, we analysed phonetic and phonological consonant characteristics of cleft palate speech (CPS) at ages 5 and 10 in cleft palate with/without cleft lip (CP±CL) based on Cleft Audit Protocol for Speech – Augmented (CAPS-A) data collected in ...
Cohen, Wendy   +3 more
core  

Speech and expressive language in Swedish-speaking children with unilateral cleft lip and palate [PDF]

open access: yes, 2014
Introduction and aims: A cleft palate may hamper development of speech and expressive language. Expressive language, including phonology, has been sparsely explored in children with cleft lip and palate, and extended knowledge is essential in order to ...
Klintö, Kristina
core   +1 more source

Top‐Down Fabricated Wood‐Derived Pressure and Strain Sensors: A Review

open access: yesAdvanced Science, EarlyView.
This review focuses on wood‐derived pressure/strain sensors fabricated via top‐down strategies. It analyzes wood's structural composition, examines processing techniques, discusses sensor types and sensing mechanisms, and reviews existing research. The article concludes with future directions for enhancing performance and scalability.
Yi Ren   +8 more
wiley   +1 more source

Success and Failure for Children Born with Facial Clefts in Africa: A 15-Year Follow-up [PDF]

open access: yes, 2018
Background: This study reviews the 15year program of our Department of Pediatric Surgery for the treatment and follow-up of children born with a cleft in Benin and Togo. Methods: We analyzed files of children born in Africa with a cleft.
Bossou, Raymond   +5 more
core  

Evidence for transforming growth factor-beta 3 gene polymorphism in non-syndromic cleft lip and palate patients from indian sub-continent [PDF]

open access: yes, 2011
Objectives: Orofacial clefts are major human birth defects with complex etiology. Previous studies have proposed Transforming growth factor - beta 3 (TGF-?3) gene as a key player in contributing to non-syndromic cleft lip and palate, however none of the ...
Banerjee, Moinak   +4 more
core   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

open access: yesAdvanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang   +13 more
wiley   +1 more source

Epidemiological pattern of cleft lip and palate under Rashtriya Bal Swasthya Karyakram project in the state of Bihar: A cross-sectional hospital-based study

open access: yesJournal of Family Medicine and Primary Care
Purpose: There is a paucity of literature on the incidence and distribution of cleft lip and palate cases in the population of Bihar leading to an unmeasured gap in the status of cleft patients in this part of the country.
Shria Datta, Veena Kumari Singh
doaj   +1 more source

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