Results 71 to 80 of about 373,896 (335)

Integrating Metabolic Modulation and Nanomedicine for Cancer Immunotherapy

Advanced Science, EarlyView.
Metabolic rewiring in cancer is mapped across glucose, amino acid, lipid, nucleotide, and mitochondrial pathways, with emphasis on immune regulation. The review integrates mechanisms linking these pathways to tumor progression and therapy resistance, and profiles nanomaterial platforms that both deliver therapeutics and actively reprogram ...
Xiaosu Zhou, Ruibing Deng, Zunde Liao, Xiaoyu Huang, Junting Huang, Hanlou Yang, Kam W. Leong, Yiling Zhong   +7 more
wiley   +1 more source

Dental anomalies inside the cleft region in individuals with nonsyndromic cleft lip with or without cleft palate [PDF]

, 2015
Background: Individuals with nonsyndromic cleft lip with or without cleft palate (NSCL±P) present high frequency of dental anomalies, which may represent complicating factors for dental treatment.
Araujo, Luana, Della Coletta, Ricardo, Guimaraes, Laís, Lopes, Gabriela, Maranhao, Samário, Medrado, Alena, Reis, Silvia, Sa, Jamile   +7 more
core   +1 more source

Ankyloglossia with cleft lip: A rare case report

Journal of Indian Society of Periodontology, 2015
Ankyloglossia or tongue-tie is a congenital anomaly affecting the tongue, which is characterized by thick, short lingual frenulum. This condition causes many difficulties such as limited tongue protrusion, breastfeeding difficulties, speech impairment ...
Kritika Jangid, Aurelian Jovita Alexander, N. Jayakumar, S. Varghese, P. Ramani   +4 more
semanticscholar   +1 more source

Challenges and Prospects of Alkali Metal Sulfide Cathodes Toward Advanced Solid‐State Metal‐Sulfur Batteries

Advanced Energy Materials, EarlyView.
This review summarizes the working mechanisms of solid‐state batteries employing alkali‐metal sulfides as cathode material. The cathodes, anodes, electrolytes, interfaces, and functional layers have been illustrated in depth. Advanced characterizations and outlooks for alkali metal sulfides‐based solid‐state batteries are elaborated in detail to guide ...
Xupeng Xu, Zengsheng Ma, Weixin Lei, Yaru Liang, Haitao Yu, Lei Zhang, Guoxin Chen, Peiling Ke, Yaojie Lei, Xiang‐Long Huang, Lingfei Zhao, Weihong Lai, Yun‐Xiao Wang, Guoxiu Wang   +13 more
wiley   +1 more source

Genetic analysis of rare disorders: Bayesian estimation of twin concordance rates [PDF]

, 2012
Twin concordance rates provide insight into the possibility of a genetic background for a disease. These concordance rates are usually estimated within a frequentistic framework. Here we take a Bayesian approach.
Berg, S.M. van den, Hjelmborg, J.
core   +5 more sources

Illuminating the Unseen and Targeting the Untreatable: Aggregation‐Induced Emission Nanoparticles as Intelligent, Immune‐Compatible Tools for Precision Cancer Theranostics

Aggregate, EarlyView.
Rationally engineered AIE nanoparticles can unite deep‐tissue imaging, photodynamic therapy, photothermal therapy, and immune microenvironment reprogramming. Through precise photophysical tuning and targeted delivery, these intelligent nanoplatforms enable real‐time monitoring, potent tumor eradication, and immune activation, offering a versatile and ...
Quazi T. H. Shubhra, Robert Musiol, Huachun Pan, Qiang Cai, Xiaosong He, Xiaojun Cai   +5 more
wiley   +1 more source

Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined

Aggregate, EarlyView.
Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei, Xikai Wang, Zhuang Hu, Jierui Yan, Xiaobo Wang, Haoran Wang, Ya Hou, Pengfei Zhang, Qihang Ding   +8 more
wiley   +1 more source

Biomedical Applications of Nanozymes: An Enzymology Perspective

Angewandte Chemie, EarlyView.
With a lens of enzymology, this review compares nanozymes with enzymes using the Michaelis‐Menten model and differences in KM and kcat along with catalysis in complex biological environment. The implications of these differences in biomedical applications of nanozymes are then described with a statistical analysis of the trend of therapeutic use of ...
Vasily G. Panferov, Xiaohan Zhang, Ka‐Ying Wong, Jung Heon Lee, Juewen Liu   +4 more
wiley   +2 more sources

Esthetic, Functional, and Everyday Life Assessment of Individuals with Cleft Lip and/or Palate

BioMed Research International, 2015
Objectives. To evaluate the level of satisfaction of individuals with cleft lip and/or palate (CLP) and their parents concerning the esthetic and functional treatment outcomes, the impact of the cleft on everyday life, and potential associations with ...
N. Gkantidis, Despina A Papamanou, Marina Karamolegkou, Domna Dorotheou   +3 more
semanticscholar   +1 more source

A Photon‐Driven Unimolecular Immunostimulant for Self‐Amplified Pyroptosis and cGAS‐STING Pathway by Destroying the Pyroptosis Checkpoint

Angewandte Chemie, EarlyView.
The proposed Bio‐Cy conjugate emerges as an avant‐garde molecular entity, adeptly activating the pyroptosis and cGAS‐STING pathways by disrupting pyroptosis checkpoints to heighten the cytocidal impact of photon‐driven immunotherapy. Abstract Immunotherapy is a groundbreaking approach for clinically treating tumors, but its effectiveness is hindered by
Shuang Zeng, Chen Chen, Zhihan Guo, Chunfang Qin, Yang Wang, Xiaosheng Liu, Xin Li, Hyunsun Jeong, Yifu Hao, Danhong Zhou, Saran Long, Zhenyong Wu, Jingyun Wang, Haidong Li, Xiaojun Peng, Juyoung Yoon   +15 more
wiley   +2 more sources