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Empowering Tomorrow’s Problem Solvers: Nexus Thinking and CLEWs Modelling as a Pedagogical Approach to Wicked Problems

Energies, 2023
The increasing prevalence of wicked problems, such as climate change, requires a transformation in education that equips students with the skills, competencies and knowledge to address these complex challenges.
Mark Howells, Richard Hodgkins, Leigh Martindale   +2 more
exaly   +6 more sources

The climate, land, energy, and water systems (CLEWs) framework: a retrospective of activities and advances to 2019 [PDF]

Environmental Research Letters, 2021
Population growth, urbanization and economic development drive the use of resources. Securing access to essential services such as energy, water, and food, while achieving sustainable development, require that policy and planning processes follow an ...
Eunice Pereira Ramos, Mark Howells, Vignesh Sridharan, Rebecka Ericsdotter Engström, Constantinos Taliotis, Dimitris Mentis, Francesco Gardumi, Lucia de Strasser, Ioannis Pappis, Gabriela Peña Balderrama, Youssef Almulla, Agnese Beltramo, Camilo Ramirez, Caroline Sundin, Thomas Alfstad, Annukka Lipponen, Eduardo Zepeda, Taco Niet, Jairo Quirós-Tortós, Jam Angulo-Paniagua, Abhishek Shivakumar, Silvia Ulloa, Holger Rogner   +22 more
doaj   +2 more sources

A dataset for climate, land, energy and water systems modelling in Lao PDRZenodo [PDF]

Data in Brief
Policymaking often treats economic and resource sectors in isolation of one another, neglecting to consider the interconnections between a country’s climate, land, energy and water (CLEW) systems.
Annie Flint Smith, Kane Alexander, Fernando A. Plazas-Niño, Mark Howells   +3 more
doaj   +2 more sources

Mid-term follow-up and outcomes of patients with prosthetic heart valves: a single-centre experience [PDF]

Echo Research and Practice, 2022
Background Patients with prosthetic heart valves (PHV) require long-term follow-up, usually within a physiologist led heart valve surveillance clinic. These clinics are well established providing safe and effective patient care.
Sadie Bennett, Polyvios Demetriades, Keely Banks, Jacopo Tafuro, Rosie Oatham, Timothy Griffiths, Cheryl Oxley, Sally Clews, Grant Heatlie, Chun Shing Kwok, Simon Duckett   +10 more
doaj   +2 more sources

Elucidating the Subcellular Localization of GLRaV-3 Proteins Encoded by the Unique Gene Block in N. benthamiana Suggests Implications on Plant Host Suppression [PDF]

Biomolecules
Grapevine leafroll-associated virus 3 (GLRaV-3) is a formidable threat to the stability of the global grape and wine industries. It is the primary etiological agent of grapevine leafroll disease (GLD) and significantly impairs vine health, fruit quality,
Patrick Lameront, Mehdi Shabanian, Laura M. J. Currie, Catherine Fust, Caihong Li, Alyssa Clews, Baozhong Meng   +6 more
doaj   +2 more sources

Identification and Characterization of Lipid Droplet-Associated Protein (LDAP) Isoforms from Tung Tree (Vernicia fordii) [PDF]

Plants
Lipid droplets (LDs) are cytoplasmic organelles responsible primarily for the storage of neutral lipids, such as triacyclglycerols (TAGs). Derived from the endoplasmic reticulum bilayer, LDs are composed of a hydrophobic lipid core encased by a ...
Alyssa C. Clews, Payton S. Whitehead, Lingling Zhang, Shiyou Lü, Jay M. Shockey, Kent D. Chapman, John M. Dyer, Yang Xu, Robert T. Mullen   +8 more
doaj   +2 more sources

Safety of routine antimicrobial prophylaxis for surgery (SAPPHIRE): a prospective multi-centre cohort study [PDF]

EClinicalMedicine
Summary: Background: Prophylactic antimicrobial drugs are routinely administered for most surgical procedures worldwide. However, the benefit may be modest and supported by low-certainty evidence, while little is known about safety in contemporary ...
Tom E.F. Abbott, Priyanthi Dias, Jai Vairale, Salma Begum, Kamran Khan, Alexander J. Fowler, Vikas Kaura, Rupert M. Pearse, Louise Savic, Tom E.F. Abbott, Priyanthi Dias, Salma Begum, Jai Vairale, Russ Hewson, Alex Fowler, Kamran Khan, Vikas Kaura, Rupert M. Pearse, Louise Savic, Louise Savic, Tom E.F. Abbott, Salma Begum, Priyanthi Dias, Kamran Khan, Vikas Kaura, Russell Hewson, Jai Vairale, Rupert M. Pearse, Tom E.F. Abbott, Louise Savic, Salma Begum, Priyanthi Dias, Alex Fowler, Vikas Kaura, Rupert M. Pearse, Robert Lewis, Tracy Griffiths, Aashima Bakshi, Katrina Cooke, Chiara De Leonardis, Edyta Klata, Emma Williams, Kerry Smith, Michelle Dotchin, Robert Lewis, Vanessa Rivers, Caitlin Palmer, Natalie Keenan, Christine Hibbert, Helen Wassall, Jan Tomkinson, Joanne Bradley-Potts, Katherine Rose, Philippa Hill, Sarah Ward, Hannah Brennan, Mohamed Mahmoud, Brendan Sloan, Mark Southworth, Anna Littlejohns, Daniel Thomas, Diana Kluczna, Nicholas Wroe, Tracy Langcake, James Roden, Chun Chiu, Jordon Almas, Matthew Howe, Rachel Murali-Krishnan, Sarah Buckley, Elizabeth Denis, Thelma Darian, Alexandra Metcalfe, Amy Major, Abigail Crew, Ronelle Mouton, Amy Dodd, Alexander Ferriman, Carmel Oliver, Edward Mew, Kate Skidmore, Kat Herneman, Richard Elston, Stella Arthur Quarm, Timothy Walker, Gayani Jayasooriya, William Turner, Sejung Park, Isabel Bradley, Ramy Mahmoud, Sunitha Eswarappa, Roshni Molls, Amanda Davis, Judith Bradley, Margaret Grout, Jackie Latimer, Muqsith Rasool, Aparna George, George Joseph, Soumyajit Saha, Tatiana Pogreban, Toko Akangadjo, Mohammed Sabihul Islam, Sanjay K. Sakholiya, Amila Herath, Marvin Mutebi, Christopher Marsh, Alison Kirby, Andrew Ike, Annette Moreton, Catherine Bressington, Jenny Pullen, Jessica Sellick, Lowri Jones, Nora Seager-Wilkendorf, Ros Knight, Rose Warren, Sara Burnard, Spandana Gumpula, Wendy Duberry, Shaman Jhanji, Holly Townsend-Renn, Anna Warrington, David Parkinson, Ethel Black, Holly Hogan, Imran Ali, Maxime Caron-Goudreau, Kayleigh Jessop, Samantha Black, Dilukshi Wickramasinghe, Linda Ofori, Lisa Parker, Patience Nkala, Thomas Gower, Tom Hatton, Trudi Chronnell, Sam Martin, George Clews, Victoria Ewasiuk, Anais Mutarambirwa, Clarissa Madla, Anil P. Hormis, Rachel Walker, Caroline Bird, Cheryl Graham, Laura Naish, Samuel Yale, Alasdair Sandland, Joyce Yeung, Helen Taylor, Jo Gresty, Juliet Sebastian, Mehwaish Zulfiqar, Meirvaan Basra, Fred Parker, Teresa Melody, Eleanor Reeves, Celina Maliaykal, Sundar Ashok, Cassandra George, Christopher Black, Islam Abousharkh, Layla Guscoth, Louise Phaure, Sophie Boles, Sreedevi Rajalingam, Rhona Sinclair, Iain J. McCullagh, Rikzing D. Bhutia, Sabrina Kapur, Wendell Storr, Adam Cookson, Adam Mowatt, Alex Wilson, Arti Gulati, Anna McHugh, Anna Surridge, Annie Newby, Benjamin Brown, Benjamin Dowdell, Cecily Christopher, Chitra Garg, George Dykes, Hezekiah Awosusi, Ian J. Storey, Jake Taylor, James Newton, Jamie McPherson, Kirsty MacLeod, Laura Heggie, Maria Mazza, Martha Smith, Melissa Hartley, Nabeel Siddiqui, Natalie Hickling, Peter Bye, Tom E.F. Abbott, Basil Nourallah, Georgina Harridge, Lucy Stephenson, Jeveria Raja, Laura Fulton, Juri Althonayan, Omar S. Ghori, Adele Mazzoleni, Aleksander Lysomirski, Fariha Rehman, Greg Titterton, James Tavner, Panayiotis Stavrinou, Ron Thomas, Salma Begum, Sarah-Louise Watson, Tom E.F. Abbott, Jonathan G. Brend, Sukhmani Sra, Imran Ali, James Matthews, James Waiting, Michael Sawaryn, Adele Mazzoleni, Aleksander Lysomirski, Alexander Ka Jun Lee, Alexey Koroshilov, Dijay Dave, Evangelia Giannas, Fariha Rehman, Fatima Seidu, Greg Titterton, James Tavner, Juri Althonayan, Kavi Thobani, Ler Tu Seah, Mareena Joseph, Omar S. Ghori, Onika Ottley, Panayiotis Stavrinou, Rakshanda Mackay, Sarah-Louise Watson, Shreya Suresh, Sophie Arthur, Ron Thomas, Jai Vairale, Timothy Martin, Bhavesh C. Gohil, Anjali Char, Aderonke Adesanoye, Alice Gao, Eamon Dhall, Francis Elechi, Freddie Weyman, Deirdre Guerin, Harry Porter, James Lambert, Lynden Nicely, Michael Sawaryn, Ruth Parker, Louise Savic, Amy Longhurst, Anna Littlejohns, Beverley Jackson, Caroline Thomas, Catherine Moriarty, Chandan Gupta, Daniel Ruane, Jack Sherlock, Joe Gleeson-Buddhdev, Kapeel Dave, Lucy Marshall, Matthew Gowshall, Mohannad Mohyeldin, Nicholas Charlesworth, Nilmini Manawaduge, Samuel Flatau, Roshan S. Verghese, Vikas Kaura, Adam Neep, Anagha Joy, Ayman Salmona, Bridie O'neill, Chloe Uffendell, Dawne Conlon, Himani Pahuja, Holly Davies, Mark Priestley, Naina Stannard, Neha Hudlikar, Oliver Ross-Smith, Rachel Holmes, Rebecca King, Rosie Wragg, Komal Ray, Amelia Milton, Aneesha Qadeer, Emma Walshaw, John Paul, John Wylde, Judith Sharp, Kanmani T. Lakshmikantha, Kate Gallagher, Michelle Naylor, Samuel Craven, Sneha Raju, Tetiana Khinalska, Zahid Furqan, Mark R. Edwards, Norma Diaper, Alice Baker, Karen Salmon, Sara Navalesi, Missy Harrison, Katie Ayyash, Alison Cairns, Bryony Shelton, Hao Ming Kevin Cheung, Edward Kenny, Ioannis Panagopoulos, Naoroz Patell, Pallavi Thakare, Thin Swe, Amrinder Sayan, Jamie Gonzales, Tamas Szakmany, Aled Rees, Angharad King, Ashley Davies, Daniel Akintelure, Luke Agace, Mai Nur Sariah M. Nasser, Mary Perkins, Robert Yates, Chiraag Talati, Deborah Elf, Alexander Rossides, Naomi Watson, Debadutta Behera, Jumainah F. Rahman, Jacqueline Davies, Alex Bird, Jade Holmes, Joanne Arnold   +341 more
doaj   +2 more sources

Transforming Arid Regions: CLEWs–OSeMOSYS Pathways for Low-Carbon Jobs and Circular Resource Loops

Energy Nexus
Arid regions face acute water scarcity, with traditional farming dominating groundwater use and employment. This study asks whether strict groundwater and carbon limits can sustain jobs while reducing emissions. Using the CLEWs–OSeMOSYS framework in Iran’
Masoumeh Bararzadeh Ledari, Maryam Fani
exaly   +3 more sources

Get a "CLEW": Using Clinical Learning Environment Walks (CLEWs) to Optimize Clinical Learning Environments. [PDF]

J Grad Med Educ, 2016
Jones WS, Maturo SC, Hutcherson LR.
europepmc   +4 more sources

ACE2 in the Gut: The Center of the 2019-nCoV Infected Pathology

Frontiers in Molecular Biosciences, 2021
The 2019-nCoV is a rapidly contagious pneumonia caused by the recently discovered coronavirus. Although generally the most noticeable symptoms are concentrated in the lungs, the disorders in the gastrointestinal tract are of great importance in the ...
Yuexin Guo, Boya Wang, Han Gao, Lei Gao, Rongxuan Hua, Jing-Dong Xu   +5 more
doaj   +1 more source