Results 41 to 50 of about 1,664 (287)
, 2022 Supplemental Material for Transparency in Non-Technical Project Summaries to Promote the Three Rs in Respiratory Disease Research by Martina Bonassera, Esther Clews and Kelly BéruBé in Alternatives to Laboratory ...
Esther Clews (5632946) +2 more
core +1 more source
Proteomics of glioblastoma based on microdissection [PDF]
Jichu yixue yu linchuangObjective To analyze differentially expressed proteins in glioblastoma(GBM) tissues and to provide potential clews for early diagnosis of glioblastoma. Methods A total of 27 formalin fixed paraffin embedded(FFPE) specimens of glioblastoma tumor tissues,
NI Yanying, ZHAI Chunyan, JIANG Zhongcai, YUAN Yuan
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Photograph of Louise Morris Clews
, 1890 Portrait of Clews at approximately 18 years old, a subject in the "Famous Beauties of Baltimore" mural located in Shriver ...
core +1 more source
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Cell Death and Disease, 2020 SRY-box transcription factors (SOXs) are effective inducers for the formation of stem-like phenotypes. As a member of SOX family, SOX9 (SRY-box transcription factor 9) has been reported to be highly expressed and exert oncogenic functions in multiple ...
Taicheng Zhou +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Understanding how ChatGPT’s political bias impacts hate speech and offensive language detection: A content analysis. [PDF]
The Young ResearcherGiven the popularity and demonstrated proficiency of ChatGPT in detecting hate speech, it is important to understand the potential influence of its left-libertarian bias in potential tasks.
Reese Clews
doaj