Results 141 to 150 of about 1,174,715 (261)

Novel Internet Advertising Approach to Raise Public Awareness About Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]

JGH Open
Inoue K, Araki K, Shibayama K, Yada T, Hara N, Oeda S, Udo K, Tobu S, Yamashita S, Isoda H, Eguchi Y, Anzai K, Noguchi M, Takahashi H.   +13 more
europepmc   +1 more source

Thyroid Click [PDF]

Journal of the Royal Society of Medicine, 1998
M C, Parker, J S, Kirkham
openaire   +2 more sources

Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction

Advanced Science, EarlyView.
This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng, Jing Sheng, Ben Niu, Wenjuan Fu, Yingjie Yang, Zuowei Xie, Shuang Xie, Yunxuan He, Meilin Gong, Jue Wang, Yan Pi, Ming Chen, Kai Chang   +12 more
wiley   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

Beyond Self-Assembly: Bioorthogonal 'Click' Chemistry Strategies for Robust Electrochemical Interfaces in Wearable Biosensors. [PDF]

Biosensors (Basel)
Merkezoğlu R, Yılmaz Ö, Kızılkurtlu AA.   +2 more
europepmc   +1 more source

Integration of the clicks and the non-clicks

Integration of the clicks and the non-clicks
application/pdf text/html 論文(Article)
openaire  

Electrolyte–Framework Matching in High‐Voltage TEMPO‐COF Cathodes for Lithium Batteries

Advanced Science, EarlyView.
TEMPO‐functionalized covalent organic frameworks are investigated as high‐voltage cathodes for lithium batteries. Screening five electrolyte anions identifies lithium difluoro(oxalato)borate (LiDFOB) as the optimal electrolyte, balancing capacity, rate capability, and cycling stability, while buckypaper electrodes achieve high mass loading (40 mg cm−2)
Marilyn Esclance DMello, Nagaraj Patil, Fanni Fekecs, Sergio Pinilla, Rebeca Marcilla, Manuel Souto   +5 more
wiley   +1 more source

Click Reactions in Kinetic Target-Guided Synthesis: Progress in the Discovery of Inhibitors for Biological Targets. [PDF]

Methods Protoc
Parvatkar PT, Satam N.
europepmc   +1 more source

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

Advanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang, Yunlong Ji, Chunwang Zhou, Xiwen Li, Zhuang Lu, Guangze Zhang, Yu Chen, Wanjiang Xue, Yilin Hu   +8 more
wiley   +1 more source

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

Advanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu, Jian Wan, Xue Zhang, Jiashuai Yan, Xi Chen, Xiaoqi Guan, Qianqian Ren, Tao Yang, Di Wu, Qingsong Guo, Yibing Guo, Yuhua Lu   +11 more
wiley   +1 more source