Results 221 to 230 of about 1,975,807 (282)

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Visualizing suborganellar lipid distribution using correlative light and electron microscopy. [PDF]

Nat Cell Biol
Lennartz HM, Khan S, Leng W, Böhlig K, Fabig G, Kieswald Y, Elsner F, Scher N, Wilsch-Bräuninger M, Avinoam O, Nadler A.   +10 more
europepmc   +1 more source

T Cell‐Independent Role of PD‐L1 in Kidney Repair: Mitigation of Tubular DNA Damage via PD‐L1/BRCA1 Interaction Following AKI

Advanced Science, EarlyView.
PD‐L1 is primarily expressed in renal tubules and upregulated in both murine models of AKI and renal biopsy samples from patients with AKI. PD‐L1 can promote adaptive TECs repair through interacting with BRCA1, independent of its canonical immunomodulatory function of T cells, and PD‐L1 supplementation may represent a promising therapeutic strategy for
Wei Jiang, Tao‐Tao Tang, Wei‐Jie Ni, Jin‐Xuan Wei, Liang‐Yun‐Zi Jiang, Qing Yin, Yi‐Lin Zhang, Zuo‐Lin Li, Yi Wen, Xin‐Lu Wang, Jun‐Yuan Shen, Xiao‐Jun Ouyang, Ming‐Zhu Zheng, Jian Xu, Xiaofei An, Lin‐Li Lv, Bi‐Cheng Liu, Bin Wang   +17 more
wiley   +1 more source

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

Click-qPCR: A Simple Tool for Interactive qPCR Data Analysis. [PDF]

Bio Protoc
Kubota A, Tajima A.
europepmc   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Health Communication Campaign Performance During the HEALing Communities Study: Cross-Sectional Examination of Digital Advertising Methods.

J Med Internet Res
Lewis N, Reynolds J, Krause D, Reeves PM, Luster J, Stein MD, Walsh SL, Farmer A, Lofwall MR, Roberts MF, Surratt HL, Crockett BN, Stephens K, Bursey K, Mattson K, Slater MD.   +15 more
europepmc   +1 more source

The Influence of Sex, Ear, and Age on Auditory Brainstem Responses Recorded with the NeuroAudio System. [PDF]

Diagnostics (Basel)
Sanfins MD, Santillo MEA, Martins MFP, Silva DLDS, Gos E, Skarzynski PH, Hall JW.   +6 more
europepmc   +1 more source

Abnormal Hearing Phenotypes in "Ignorome" Knockout Mice as Predictors of Cognitive Dysfunction. [PDF]

Genes Brain Behav
Vicencio-Jimenez S, Dent ML, Lauer AM.
europepmc   +1 more source

Anisotropic gold nanochains with dual-ligand interfaces for theranostic immune activation. [PDF]

RSC Adv
Yang C, Son YJ, Jin S, Park Y, Jung YM, Kang SG, Yoo HS.   +6 more
europepmc   +1 more source