Results 171 to 180 of about 1,698 (209)
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The impact of click chemistry in medicinal chemistry
Expert Opinion on Drug Discovery, 2012The copper(I)-catalyzed 1,3-dipolar cycloaddition of alkynes and azides to form 1,2,3-triazoles is the most popular reaction in click chemistry. This reaction is also near-perfect, in terms of its robustness, due to the high degree of reliability and complete specificity.
Jingli Hou +2 more
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Angewandte Chemie - International Edition, 2010
AbstractFollowing Sharpless′ visionary characterization of several idealized reactions as click reactions, the materials science and synthetic chemistry communities have pursued numerous routes toward the identification and implementation of these click reactions.
Charles E Hoyle, Christopher N Bowman
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AbstractFollowing Sharpless′ visionary characterization of several idealized reactions as click reactions, the materials science and synthetic chemistry communities have pursued numerous routes toward the identification and implementation of these click reactions.
Charles E Hoyle, Christopher N Bowman
exaly +3 more sources
RCSB Protein Data Bank, 2022
Clickchemistry is a discipline that has developed rapidly over the past two decades. In this Thieme WebCheminar, Floris Rutjes (SOS Editor of ‘Click Chemistry’) and SOS authors Hannes Mikula and John Moses will discuss recent progress in click and bioorthogonal chemistry.
Hannes Mikula, John E. Moses
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Clickchemistry is a discipline that has developed rapidly over the past two decades. In this Thieme WebCheminar, Floris Rutjes (SOS Editor of ‘Click Chemistry’) and SOS authors Hannes Mikula and John Moses will discuss recent progress in click and bioorthogonal chemistry.
Hannes Mikula, John E. Moses
+5 more sources
Click Chemistry with Ynamides.
ChemInform, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Maarten IJsselstijn +1 more
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Click Chemistry with Polysaccharides
Macromolecular Rapid Communications, 2006AbstractSummary: The copper‐catalyzed Huisgen reaction as a typical example of click chemistry was realized with the polysaccharide cellulose for the first time. The generality, selectivity, and the efficiency of click chemistry perfectly fit the requirements of polysaccharide modification, which is demonstrated by the introduction of triazole‐spacer ...
Liebert, T., Hänsch, C., Heinze, T.
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Click chemistry at the microscale
The Analyst, 2019This manuscript reviews recent developments in click chemistry in microscale systems.
Tingting Hong +3 more
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The growing applications of click chemistry
Chem. Soc. Rev., 2007AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
John E, Moses, Adam D, Moorhouse
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Ultrafast Click Chemistry with Fluorosydnones
Angewandte Chemie International Edition, 2016AbstractWe report the synthesis and reactivity of 4‐fluorosydnones, a unique class of mesoionic dipoles displaying exquisite reactivity towards both copper‐catalyzed and strain‐promoted cycloaddition reactions with alkynes. Synthetic access to these new mesoionic compounds was granted by electrophilic fluorination of σ‐sydnone PdII precursors in the ...
Liu, Hui +13 more
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Click chemistry in sphingolipid research
Chemistry and Physics of Lipids, 2018The term "click chemistry" was firstly coined by K. B. Sharpless in 2001 to refer to reactions that are high yielding, wide in scope, produce only easily removable byproducts and are stereospecific and simple to perform. Since then, this concept has been further developed and a large number of chemical reactions that fulfil totally or partially these ...
Eduardo Izquierdo, Antonio Delgado
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Light-Triggered Click Chemistry
Chemical Reviews, 2020The merging of click chemistry with discrete photochemical processes has led to the creation of a new class of click reactions, collectively known as photoclick chemistry. These light-triggered click reactions allow the synthesis of diverse organic structures in a rapid and precise manner under mild conditions.
Gangam Srikanth Kumar, Qing Lin
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