Results 1 to 10 of about 71,291 (332)

Azides in the Synthesis of Various Heterocycles

Molecules, 2022
In this review, we focus on some interesting and recent examples of various applications of organic azides such as their intermolecular or intramolecular, under thermal, catalyzed, or noncatalyzed reaction conditions.
AbdElAziz A. Nayl, Ashraf A. Aly, Wael A. A. Arafa, Ismail M. Ahmed, Ahmed I. Abd-Elhamid, Esmail M. El-Fakharany, Mohamed A. Abdelgawad, Hendawy N. Tawfeek, Stefan Bräse   +8 more
doaj   +4 more sources

Chemoselectivity of Tertiary Azides in Strain-Promoted Alkyne-Azide Cycloadditions [PDF]

Chemistry – A European Journal, 2019
The strain-promoted alkyne-azide cycloaddition (SPAAC) is the most commonly employed bioorthogonal reaction with applications in a broad range of fields.
Svatunek, Dennis, Mikula, Hannes, Houszka, Nicole, Bickelhaupt, F.Matthias, Bickelhaupt, F. Matthias, Hamlin, Trevor A.; id_orcid, Trevor A. Hamlin, Nicole Houszka, F. Matthias Bickelhaupt, Hamlin, Trevor A., Dennis Svatunek, Hannes Mikula   +11 more
core   +8 more sources

Application of Vinyl Azides in Chemical Synthesis: A Recent Update

Journal of Organic Chemistry, 2017
Among organic azides, vinyl azides have shown versatile chemical reactivities in the recent development of new synthetic methodologies mainly for nitrogen-containing molecules. This synopsis highlights and discusses recent advances on use of vinyl azides
Atsushi Kaga, Shunsuke Chiba
exaly   +3 more sources

Reactive & Efficient: Organic Azides as Cross-Linkers in Material Sciences

Molecules, 2020
The exceptional reactivity of the azide group makes organic azides a highly versatile family of compounds in chemistry and the material sciences. One of the most prominent reactions employing organic azides is the regioselective copper(I)-catalyzed ...
Marvin Schock, Stefan Bräse
doaj   +2 more sources

4-Sulfanyl-1,2,3-triazole as a Powerful Ligand in CuAAC to Synthesize 1,4-Substituted 1,2,3-Triazoles Under Solvent-Free and Low Catalyst Loading [PDF]

Molecules
4-Sulfanyl-1,2,3-triazole (L1) accelerated the solvent-free CuAAC efficiently with low catalyst loading (0.1 mol% for common azides and 1 mol% for sulfonyl azides). L1 exhibited higher catalytic activity compared to 1,4-substituted 1,2,3-triazole without
Jie Shen, Jinwei Li, Shitang Xu, Ting Wang, Zhiling Zou, Hui Li, Lifen Peng, Zilong Tang, Xinhua Xu   +8 more
doaj   +2 more sources

Pyrolysis of aryl azides. II. Naphthyl azides

Australian Journal of Chemistry, 1972
Kinetic studies of the pyrolyses of 1- and 2-naphthyl azides reveal neighbouring group participation by nitro and phenylazo substituents. The acceleration observed in 1-nitro-2-naphthyl azide, 1-phenylazo-2-naphthyl azide, and 2-nitro-1-naphthyl azide is
G Boshev, PR Sadler, LK Dyall
core   +2 more sources

SulfoxFluor-enabled deoxyazidation of alcohols with NaN3

Nature Communications, 2022
Azides are common moieties in chemical synthesis. Here the authors present a methodology to synthesize alkyl azides in one step from simple alcohols under mild conditions.
Junkai Guo, Xiu Wang, Chuanfa Ni, Xiaolong Wan, Jinbo Hu   +4 more
doaj   +1 more source

Ortho-Phosphinoarenesulfonamide-Mediated Staudinger Reduction of Aryl and Alkyl Azides

Molecules, 2022
Conventional Staudinger reductions of organic azides are sluggish with aryl or bulky aliphatic azides. In addition, Staudinger reduction usually requires a large excess of water to promote the decomposition of the aza-ylide intermediate into phosphine ...
Xingzhuo Li, Zhenguo Wang, Wenjun Luo, Zixu Wang, Keshu Yin, Le Li   +5 more
doaj   +1 more source

Taming Unhindered Alkyl Azides by Intramolecular Hydrogen-Azide Interaction for Discriminative Conjugation onto Alkyl Diazides

, 2021
We report herein the unique reactivities of α-azido secondary acetamides (α-AzSAs) as minimal and unhindered azide structures. The NH–azide interaction in the α-AzSAs, supposed by DFT calculation, allowed selective conjugation in the presence of other ...
Koshiro, Maegawa, Kiyomi, Kakiuchi, Takenori, Tomohiro, Seiji, Onishi, Hiroki, Tanimoto, Tsumoru, Morimoto   +5 more
core   +1 more source

Kinetic resolution of cyclic benzylic azides enabled by site- and enantioselective C(sp3)–H oxidation

Nature Communications, 2022
Catalytic kinetic resolution of racemates is among the best ways to prepare enantiopure compounds, but this process is difficult with organic azides given the small size of the azido group.
Pengbo Ye, Aili Feng, Lin Wang, Min Cao, Rongxiu Zhu, Lei Liu   +5 more
doaj   +1 more source