Differentiation between Isomeric 4,5-Functionalized 1,2,3-Thiadiazoles and 1,2,3-Triazoles by ESI-HRMS and IR Ion Spectroscopy [PDF]
Molecules, 2023 A large variety of 1,2,3-thiadiazoles and 1,2,3-triazoles are used extensively in modern pure and applied organic chemistry as important structural blocks of numerous valuable products.
Dmitrii M. Mazur +6 more
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Reaction of 4-acetyl-1,2,3-triazol-5-olate with hydrazine derivatives [PDF]
Chimica Techno Acta, 2015 1,2,3-triazole attracts attention because of the ability opening ring to form α-diazoimin and intramolecular rearrangements with the formation of various heterocyclic systems.
I. S. Khazhieva +2 more
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Triazoles and Their Derivatives: Chemistry, Synthesis, and Therapeutic Applications
Frontiers in Molecular Biosciences, 2022 Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Structurally, there are two types of five-membered triazoles: 1,2,3-triazole and 1,2,4-triazole.
Mohammed Mahbubul Matin +2 more
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4,5-Bis(arylethynyl)-1,2,3-triazoles—A New Class of Fluorescent Labels: Synthesis and Applications [PDF]
Molecules, 2022 Cu-catalyzed 1,3-dipolar cycloaddition of ethyl 2-azidoacetate to iodobuta-1,3-diynes and subsequent Sonogashira cross-coupling were used to synthesize a large series of new triazole-based push–pull chromophores: 4,5-bis(arylethynyl)-1H-1,2,3-triazoles ...
Anastasia I. Govdi +7 more
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Copper-Catalyzed Synthesis of 4-CF3-1,2,3-Triazoles: An Efficient and Facile Approach via Click Reaction [PDF]
MoleculesIncorporation of a trifluoromethyl group with 1,2,3-triazoles motifs was described. We explored a click reaction approach for regioselective synthesis of 1-susbstituted-4-trifluoromethyl-1,2,3-triazoles in which 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU ...
Tinghong Tang +5 more
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Enantioselective copper-catalyzed azidation/click cascade reaction for access to chiral 1,2,3-triazoles [PDF]
Nature CommunicationsChiral 1,2,3-triazoles are highly attractive motifs in various fields. However, achieving catalytic asymmetric click reactions of azides and alkynes for chiral triazole synthesis remains a significant challenge, mainly due to the limited catalytic ...
Ling-Feng Jiang +9 more
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Fe3O4@HA-Cu(OAc)2 nanocomposite as a nanomagnetic water-compatible catalyst for efficient synthesis of 1,2,3-triazoles in water [PDF]
Scientific ReportsA new humic acid-based nanomagnetic copper(II) composite was prepared and used as an eco-friendly recoverable catalyst for synthesizing 1,4-disubstituted 1,2,3-triazoles.
Beheshteh Arjmandzadeh, Abbas Ali Jafari
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Журнал органічної та фармацевтичної хімії, 2022 Aim. To analyze and summarize the synthetic potential of 1,2,3-triazole-4(5)-amines as efficient building blocks in the synthesis of triazolo-annulated pyridine, azine and azepine systems. Results and discussion.
Natalia O. Syrota +3 more
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Molecules, 2022 An operationally simple Ag(I)-catalyzed approach for the synthesis of isoquinoline and quinazoline fused 1,2,3-triazoles was developed by a condensation and amination cyclization cascade of amino-NH-1,2,3-triazoles with 2-alkynylbenzaldehydes involving ...
Shuitao Zhang +4 more
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Overview of 1,5-Selective Click Reaction of Azides with Alkynes or Their Synthetic Equivalents
Molecules, 2023 Nowadays, the click reaction of azides with alkynes has evolved rapidly and become one of the most efficient methods to synthesize 1,2,3-triazoles, which are an important class of N-containing heterocycles.
Yaqi Zhao +3 more
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