Results 1 to 10 of about 43,142 (242)

A Regioselective Approach to Accessing Trisubstituted Pyrrolo[2,3-d][1,2,3]triazoles via an Orthogonal Protection Strategy [PDF]

Molecules
The first access to N-2, N-4-disubstituted pyrrolo[2,3-d][1,2,3]triazoles is reported herein. The series was generated using an orthogonal protecting group strategy from N-1, N-4-disubtituted pyrrolo[2,3-d][1,2,3]triazoles. N-Arylation by Ullman–Goldberg
Kévin Brugemann, Simon Garnier, Johnny Vercouillie, Sylvain Routier, Frédéric Buron   +4 more
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4-Sulfanyl-1,2,3-triazole as a Powerful Ligand in CuAAC to Synthesize 1,4-Substituted 1,2,3-Triazoles Under Solvent-Free and Low Catalyst Loading [PDF]

Molecules
4-Sulfanyl-1,2,3-triazole (L1) accelerated the solvent-free CuAAC efficiently with low catalyst loading (0.1 mol% for common azides and 1 mol% for sulfonyl azides). L1 exhibited higher catalytic activity compared to 1,4-substituted 1,2,3-triazole without
Jie Shen, Jinwei Li, Shitang Xu, Ting Wang, Zhiling Zou, Hui Li, Lifen Peng, Zilong Tang, Xinhua Xu   +8 more
doaj   +2 more sources

Copper-Catalyzed Synthesis of 4-CF₃-1,2,3-Triazoles: An Efficient and Facile Approach via Click Reaction [PDF]

Molecules
Incorporation of a trifluoromethyl group with 1,2,3-triazoles motifs was described. We explored a click reaction approach for regioselective synthesis of 1-susbstituted-4-trifluoromethyl-1,2,3-triazoles in which 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU ...
Tinghong Tang, Cuiting Chen, Xin Fu, Huilan Xu, Luyong Wu, Wenhao Chen   +5 more
doaj   +2 more sources

Enantioselective copper-catalyzed azidation/click cascade reaction for access to chiral 1,2,3-triazoles [PDF]

Nature Communications
Chiral 1,2,3-triazoles are highly attractive motifs in various fields. However, achieving catalytic asymmetric click reactions of azides and alkynes for chiral triazole synthesis remains a significant challenge, mainly due to the limited catalytic ...
Ling-Feng Jiang, Shao-Hua Wu, Yu-Xuan Jiang, Hong-Xiang Ma, Jia-Jun He, Yang-Bo Bi, De-Yi Kong, Yi-Fei Cheng, Xuan Cheng, Qing-Hai Deng   +9 more
doaj   +2 more sources

1,2,3-Triazole-4(5)-amines – Convenient Synthetic Blocks for the Construction of Triazolo-Annulated Heterocycles

Журнал органічної та фармацевтичної хімії, 2022
Aim. To analyze and summarize the synthetic potential of 1,2,3-triazole-4(5)-amines as efficient building blocks in the synthesis of triazolo-annulated pyridine, azine and azepine systems. Results and discussion.
Natalia O. Syrota, Sergiy V. Kemskiy, Lesya M. Saliyeva, Mykhailo V. Vovk   +3 more
doaj   +1 more source

Overview of 1,5-Selective Click Reaction of Azides with Alkynes or Their Synthetic Equivalents

Molecules, 2023
Nowadays, the click reaction of azides with alkynes has evolved rapidly and become one of the most efficient methods to synthesize 1,2,3-triazoles, which are an important class of N-containing heterocycles.
Yaqi Zhao, Zhengqi Chai, Qingrui Zeng, Wen-Xiong Zhang   +3 more
doaj   +1 more source

Silver-Catalyzed Cascade Cyclization of Amino-NH-1,2,3-Triazoles with 2-Alkynylbenzaldehydes: An Access to Pentacyclic Fused Triazoles

Molecules, 2022
An operationally simple Ag(I)-catalyzed approach for the synthesis of isoquinoline and quinazoline fused 1,2,3-triazoles was developed by a condensation and amination cyclization cascade of amino-NH-1,2,3-triazoles with 2-alkynylbenzaldehydes involving ...
Shuitao Zhang, Jianxin Li, Tiebo Xiao, Baomin Yang, Yubo Jiang   +4 more
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Differentiation between Isomeric 4,5-Functionalized 1,2,3-Thiadiazoles and 1,2,3-Triazoles by ESI-HRMS and IR Ion Spectroscopy

Molecules, 2023
A large variety of 1,2,3-thiadiazoles and 1,2,3-triazoles are used extensively in modern pure and applied organic chemistry as important structural blocks of numerous valuable products.
Dmitrii M. Mazur, Elettra L. Piacentino, Giel Berden, Jos. Oomens, Victor Ryzhov, Vasiliy A. Bakulev, Albert T. Lebedev   +6 more
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Three-component synthesis of 1,2,3-triazoles in the presence of PVC-supported triazole-copper complex by click reaction [PDF]

شیمی کاربردی روز, 2020
In this research work novel PVC-supported triazole-copper(I) iodide catalyst (PVC–Triazole–CuI) was prepared and used the for synthesis of 1,2,3-triazoles.
Ali Keivanloo, Mostafa Gholizadeh, Elnaz Rezaii   +2 more
doaj   +1 more source

5-Formyltriazoles as Valuable Starting Materials for Unsymmetrically Substituted Bi-1,2,3-Triazoles

Frontiers in Chemistry, 2020
Herein, we present the first synthetic methodologies toward non-symmetrical 5,5′-C, C-linked bi-1,2,3-triazoles starting from 5-formyl-1,2,3-triazole via two related pathways.
Robby Vroemans, Tomas Horsten, Maarten Van Espen, Wim Dehaen   +3 more
doaj   +1 more source