Results 31 to 40 of about 12,017 (229)

Coordinatively unsaturated ruthenium complexes as efficient alkyne-azide cycloaddition catalysts [PDF]

, 2012
The performance of 16-electron ruthenium complexes with the general formula Cp*Ru(L)X (in which L = phosphine or N-heterocyclic carbene ligand; X = Cl or OCH2CF3) was explored in azide−alkyne cycloaddition reactions that afford the 1,2,3- triazole ...
Broggi, Julie, Cavallo, Luigi, Fortman, George C., Lamberti, Marina, Nolan, Steven P., Poater, Albert, Slawin, Alexandra M. Z.   +6 more
core   +2 more sources

Preparation of Quinoline-2,4-dione Functionalized 1,2,3-Triazol-4-ylmethanols, 1,2,3-Triazole-4-carbaldehydes and 1,2,3-Triazole-4-carboxylic Acids

Acta Chimica Slovenica, 2020
(1-(2,4-Dioxo-1,2,3,4-tetrahydroquinolin-3-yl)-1H-1,2,3-triazol-4-yl)methyl acetates substituted on nitrogen atom of quinolinedione moiety with propargyl group or (1-substituted 1H-1,2,3-triazol-4-yl)methyl group, which are available from the appropriate 3-(4-hydroxymethyl-1H-1,2,3-triazol-1-yl)quinoline-2,4(1H,3H)-diones unsubstituted on quinolone ...
Milićević, David, Kimmel, Roman, Urankar, Damijana, Pevec, Andrej, Kosmrlj, Janez, Kafka, Stanislav   +5 more
openaire   +5 more sources

Ruthenium-catalyzed azide alkyne cycloaddition reaction: scope, mechanism and applications [PDF]

, 2016
The ruthenium-catalyzed azide alkyne cycloaddition (RuAAC) affords 1,5-disubstituted 1,2,3-triazoles in one step and complements the more established copper-catalyzed reaction providing the 1,4-isomer.
Akimova G., Akimova G., Akimova G., Anna Said Stålsmeden, Bader R. F. W., Chandrasekaran S., Das R., Fan W.-Q., Fokin V. V., Gruchlik A., Huisgen R., Johan R. Johansson, Keicher T., Levin J. I., Murahashi S.-I., Neumajer G., Nina Kann, Palaniraja J., Parsons J. G., Schilling C., Tamás Beke-Somfai, Trabocchi A., Yubo J., Zhou Y. B.   +23 more
core   +2 more sources

Transformations of 1-(Oxiranylmethyl)-1,2,3-triazoles into 2-(Oxiranyl­methyl)-1,2,3-triazoles and Alkanenitriles [PDF]

Synlett, 2012
New reactions for the transformation of 1-(oxiranylmethyl)-1,2,3-triazoles into 2-(oxiranylmethyl)-1,2,3-triazoles or alkanenitriles were established. Successive treatment of the substrate with triflic acid and t-BuOH afforded 4,6-dihydro-5-hydroxy-1,3a,6a-triazapentalene derivative.
Osawa, Ayumi, Mera, Akane, Namba, Kosuke, Tanino, Keiji   +3 more
openaire   +2 more sources

Diazo Transfer From Nitrous Oxide Employing Phosphorus Ylides

Angewandte Chemie, EarlyView.
A phosphorus ylide‐mediated strategy achieves the direct fixation of nitrous oxide (N2O) to access diazo compounds, which after intra‐ or intermolecular trapping, afford N2‐containing organic building blocks. This approach provides an alternative to hazardous diazo‐transfer reagents and establishes N2O fixation as a sustainable methodology.
Jhen‐Kuei Yu, Jan Niclas Ludwig, Patrick Wolf Antoni, David Tymann, Max Martin Hansmann   +4 more
wiley   +2 more sources

Synthesis of N1 and N2 coumarin substituted 1,​2,​3-​triazole isomers via click chemistry approach [PDF]

, 2016
The synthesis of N1 and N2 coumarin substituted 1,​2,​3-​triazole isomers from terminal alkynes, sodium azide, and 4-​bromomethylcoumarins in the presence of triethylamine as a base and CuI as a catalyst in good yield were reported. The mol.
Chandra, ., Mahendra Madegowda, ., Shamala Devadas, ., Shivashankar Kalegowda, .   +3 more
core   +1 more source

Click Chemistry: 1,2,3‐Triazoles as Pharmacophores [PDF]

Chemistry – An Asian Journal, 2011
AbstractThe copper(I)‐catalyzed 1,2,3‐triazole‐forming reaction between azides and terminal alkynes has become the gold standard of ‘click chemistry’ due to its reliability, specificity, and biocompatibility. Applications of click chemistry are increasingly found in all aspects of drug discovery; they range from lead finding through combinatorial ...
Sandip G, Agalave, Suleman R, Maujan, Vandana S, Pore   +2 more
openaire   +2 more sources

Microwave assisted metal-free approach to access 1,2,3-triazoles through multicomponent synthesis

Current Research in Green and Sustainable Chemistry, 2020
The work illustrates multicomponent reaction of aldehydes, nitroalkanes and sodium azide for the metal-free synthesis of N-unsubstituted-1,2,3-triazoles using anthranilic acid as an organocatalyst under microwave irradiation. This is the first ever green
Anirban Garg, Diganta Sarma, Abdul Aziz Ali   +2 more
doaj   +1 more source

Synthesis of new 1,4-disubstituted 1,2,3-triazoles using the CuAAC reaction and determination of their antioxidant activities

Anais da Academia Brasileira de Ciências, 2021
This study describes the synthesis and antioxidant activity of new 1,4-disubstituted 1,2,3-triazoles. These compounds were generated semi-synthetically using the Cu(I)-catalysed azide-alkyne cycloaddition (CuAAC) reaction between ethyl 2-azidoacetate and
JOSEFA A. DA CUNHA LIMA, JADSON DE FARIAS SILVA, COSME S. SANTOS, RODRIGO R.A. CAIANA, MARCÍLIO M. DE MORAES, CLAUDIO A.G. DA CÂMARA, JULIANO C.R. FREITAS   +6 more
doaj   +1 more source

Synthesis of 1,2,3-triazole functionalized hyperbranched poly(ethyleneimine) and its use as multifunctional anionic macroinitiator for diglycidyl ether of bisphenol A curing [PDF]

, 2016
Hyperbranched poly(ethyleneimine) (PEI) has been modified by the addition of propargyl acrylate following a Michael addition reaction. On this polymer (PEI-yne) a copper (I)-catalyzed azide alkyne cycloaddition (CuAAC) has been performed to obtain a ...
Acebo Gorostiza, Cristina, Appelhans, Dietmar, Lederer, Albena, Ramis Juan, Xavier, Serra Albet, Àngels   +4 more
core   +2 more sources