Assembly drives regioselective azide-alkyne cycloaddition reaction [PDF]
Nature Communications, 2023 Azide-alkyne cycloaddition reaction is a very common organic reaction to synthesize nitrogen-containing heterocycles. Once catalyzed by Cu(I) or Ru(II), it turns out to be a click reaction and thus is widely applied in chemical biology for labeling ...
Qiaochu Jiang +6 more
doaj +2 more sources
Advances in the Synthesis of Fused 1,2,3-Triazoles via a MCR-Intramolecular Azide-Alkyne Cycloaddition Approach [PDF]
Molecules, 2022 The present review narrates several reports which deal with the synthesis of fused 1,2,3-triazole containing scaffolds following a sequential multicomponent reaction (MCR)—intramolecular azide-alkyne cycloaddition (IAAC) approach.
Rahul P +3 more
doaj +2 more sources
Synthesis of Bioconjugation Reagents for Use in Covalent Cross-Linking of Proteins by Azide-Alkyne Cycloaddition [PDF]
MoleculesA series of azide- and cyclooctyne-functionalized N-hydroxysuccinimidyl esters (NHS esters) and benzotriazolides were prepared and used as N-acylation reagents to obtain azide-(BSA-1) and cyclooctyne-functionalized bovine serum albumin proteins (BSA-2 ...
Nadja Suhorepec +6 more
doaj +2 more sources
Chemical Architecture and Applications of Nucleic Acid Derivatives Containing 1,2,3-Triazole Functionalities Synthesized via Click Chemistry [PDF]
Molecules, 2012 There is considerable attention directed at chemically modifying nucleic acids with robust functional groups in order to alter their properties. Since the breakthrough of copper-assisted azide-alkyne cycloadditions (CuAAC), there have been several ...
Wei Gong +2 more
doaj +3 more sources
Efficient catenane synthesis by cucurbit[6]uril-mediated azide–alkyne cycloaddition [PDF]
Beilstein Journal of Organic Chemistry, 2018 We report here the efficient synthesis of a series of [3]catenanes featuring the use of cucurbit[6]uril to simultaneously mediate the mechanical and covalent bond formations.
Antony Wing Hung Ng +3 more
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Catalysis Communications, 2023 The demand for environmental friendly methodologies had shifted the the approach of scientific community for using easy and green reaction conditions instead of using hazardous and harsh reaction conditions.
Vijay Kumar +3 more
doaj +1 more source
Direct Light-up of cAMP Derivatives in Living Cells by Click Reactions
Molecules, 2013 8-Azidoadenosine 3′,5′-cyclic monophosphate (8-azido cAMP) was directly detected in living cells, by applying Cu-free azide-alkyne cycloaddition to probe cAMP derivatives by fluorescence light-up.
Yan Xu +4 more
doaj +1 more source
Copper-catalyzed Z-selective synthesis of acrylamides and polyacrylamides via alkylidene ketenimines
Nature Communications, 2022 Alkylidene ketenimines are rarely reported, but synthetically useful, reactive intermediates. Here, the authors disclose a three-component reaction of alkyne, azide and water by cycloaddition, nitrogen extrusion, and carbene-assisted rearrangement, via ...
Xuelun Duan +6 more
doaj +1 more source
Pullulan-Graft-Polyoxazoline: Approaches from Chemistry and Physics
Molecules, 2023 An approach to the preparation of pullulan-graft-poly(2-methyl-2-oxazoline)s based on Cu-catalyzed azide–alkyne cycloaddition with polyoxazoline-azide was applied.
Ivan M. Zorin +8 more
doaj +1 more source
Coordinatively unsaturated ruthenium complexes as efficient alkyne-azide cycloaddition catalysts [PDF]
, 2012 The performance of 16-electron ruthenium complexes with the general formula Cp*Ru(L)X (in which L = phosphine or N-heterocyclic carbene ligand; X = Cl or OCH2CF3) was explored in azide−alkyne cycloaddition reactions that afford the 1,2,3- triazole ...
Broggi, Julie +6 more
core +2 more sources