Results 11 to 20 of about 97,080 (283)

Advances in the Synthesis of Fused 1,2,3-Triazoles via a MCR-Intramolecular Azide-Alkyne Cycloaddition Approach. [PDF]

Molecules, 2022
The present review narrates several reports which deal with the synthesis of fused 1,2,3-triazole containing scaffolds following a sequential multicomponent reaction (MCR)—intramolecular azide-alkyne cycloaddition (IAAC) approach.
P R, Thomas J, Dehaen W, John J.
europepmc   +2 more sources

Conditional Copper-Catalyzed Azide-Alkyne Cycloaddition by Catalyst Encapsulation. [PDF]

Angew Chem Int Ed Engl, 2020
Supramolecular encapsulation is known to alter chemical properties of guest molecules. Here we apply this strategy of molecular encapsulation to temporally control the catalytic activity of a stable Cu(I)-carbene catalyst.
Brevé TG, Filius M, Araman C, van der Helm MP, Hagedoorn PL, Joo C, van Kasteren SI, Eelkema R.   +7 more
europepmc   +2 more sources

Synthesis of Bioconjugation Reagents for Use in Covalent Cross-Linking of Proteins by Azide-Alkyne Cycloaddition. [PDF]

Molecules
A series of azide- and cyclooctyne-functionalized N-hydroxysuccinimidyl esters (NHS esters) and benzotriazolides were prepared and used as N-acylation reagents to obtain azide-(BSA-1) and cyclooctyne-functionalized bovine serum albumin proteins (BSA-2 ...
Suhorepec N, Ciber L, Grošelj U, Petek N, Štefane B, Novinec M, Svete J.   +6 more
europepmc   +2 more sources

The fate of heterogeneous catalysis & click chemistry for 1,2,3-triazoles: Nobel prize in chemistry 2022

Catalysis Communications, 2023
The demand for environmental friendly methodologies had shifted the the approach of scientific community for using easy and green reaction conditions instead of using hazardous and harsh reaction conditions.
Vijay Kumar, Kashmiri Lal, Naveen, Ram Kumar Tittal   +3 more
doaj   +1 more source

Alkyne-Substituted Deoxybenzoins as Precursors to Cycloaddition Chemistry and the Preparation of Low-Flammability Polymers and Blends

, 2023
We report the synthesis and characterization of novel alkyne-substituted deoxybenzoins that are setup for azide–alkyne cycloaddition chemistry to yield oligomeric and polymeric structures that exhibit useful thermal properties, both on their own and as ...
Chien-Han Chen (5117024), Krishnamurthy Munusamy (17383013), Todd Emrick (1286913)   +2 more
core   +6 more sources

Untargeted identification of alkyne containing natural products using ruthenium catalyzed azide alkyne cycloaddition reactions coupled to LC-MS/MS.

, 2021
Alkyne containing natural products have been identified from plants, insects, algae, fungi, and bacteria. This class of natural products have been characterized as having a variety of biological activities.
Daniel , Back, Joyce, Loper, Benjamin, Philmus, Brenda, Shaffer   +3 more
core   +1 more source

New catalytic strategies for DNA and RNA alkylation using rhodium (II) and copper (I) carbenes - a versatile tool for applications in chemical biology [PDF]

, 2015
A variety of nucleic acid substrates were catalytically alkylated with rhodium(II) and copper(I)-carbenoids generated from diazocarbonyl compounds. The alkylation took place via an N-H insertion reaction selectively targeting the nucleobases in single ...
Tishinov, Kiril
core   +1 more source

Direct Light-up of cAMP Derivatives in Living Cells by Click Reactions

Molecules, 2013
8-Azidoadenosine 3′,5′-cyclic monophosphate (8-azido cAMP) was directly detected in living cells, by applying Cu-free azide-alkyne cycloaddition to probe cAMP derivatives by fluorescence light-up.
Yan Xu, Hongshan Liu, Tetsuya Hayashi, Makoto Komiyama, Kenichiro Ito   +4 more
doaj   +1 more source

Copper-catalyzed Z-selective synthesis of acrylamides and polyacrylamides via alkylidene ketenimines

Nature Communications, 2022
Alkylidene ketenimines are rarely reported, but synthetically useful, reactive intermediates. Here, the authors disclose a three-component reaction of alkyne, azide and water by cycloaddition, nitrogen extrusion, and carbene-assisted rearrangement, via ...
Xuelun Duan, Nan Zheng, Ming Li, Gongbo Liu, Xinhao Sun, Qiming Wu, Wangze Song   +6 more
doaj   +1 more source

Pullulan-Graft-Polyoxazoline: Approaches from Chemistry and Physics

Molecules, 2023
An approach to the preparation of pullulan-graft-poly(2-methyl-2-oxazoline)s based on Cu-catalyzed azide–alkyne cycloaddition with polyoxazoline-azide was applied.
Ivan M. Zorin, Petr A. Fetin, Nina G. Mikusheva, Alexey A. Lezov, Igor Perevyazko, Alexander S. Gubarev, Anna N. Podsevalnikova, Sergey G. Polushin, Nikolai V. Tsvetkov   +8 more
doaj   +1 more source