Results 1 to 10 of about 210,123 (350)
Synthesis of β-Difluoroalkyl Azides via Elusive 1,2-Azide Migration
CheM, 2020 Summary The development of azide migration reactions is a formidable challenge because of the potential competition of side processes driven by the release of molecular nitrogen.
Yongquan Ning, Ed Anderson, Xihe Bi
exaly +2 more sources
Ruthenium-Catalyzed Azide Alkyne Cycloaddition Reaction: Scope, Mechanism, and Applications
Chemical Reviews, 2016 The ruthenium-catalyzed azide alkyne cycloaddition (RuAAC) affords 1,5-disubstituted 1,2,3-triazoles in one step and complements the more established copper-catalyzed reaction providing the 1,4-isomer.
Nina Kann +2 more
exaly +2 more sources
Chemoselectivity of Tertiary Azides in Strain‐Promoted Alkyne‐Azide Cycloadditions [PDF]
Chemistry – A European Journal, 2018 The strain‐promoted alkyne‐azide cycloaddition (SPAAC) is the most commonly employed bioorthogonal reaction with applications in a broad range of fields.
D. Svatunek +4 more
semanticscholar +6 more sources
Analysis and Optimization of Copper-Catalyzed Azide–Alkyne Cycloaddition for Bioconjugation
Angewandte Chemie - International Edition, 2009 Since its discovery in 2002, the copper-catalyzed azide-alkyne cycloaddition (CuAAC)[1] reaction—the most widely recognized example of click chemistry[2]—has been rapidly embraced for applications in myriad fields.[3] The attractiveness of this procedure
MG Finn, M G Finn
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Facile fabrication of polymer network using click chemistry and their computational study [PDF]
Royal Society Open Science, 2021 Click reaction is a very fast, high yield with no by-product, biocompatible, tolerant to surrounded medium, and very specific cycloaddition reaction between azides and alkynes to form triazole.
Md. Kausar Ahmed +2 more
doaj +1 more source
Azide-Alkyne Cycloaddition Catalyzed by a Glucose/Benedict Reagent System
Chemistry Proceedings, 2021 Benedict’s Reagent is commonly used in identifying reducing sugars through a redox process where a Cu(I) species is generated. Despite the simplicity of this reaction, this has barely been investigated as a copper (I) source for catalytic processes.
Jesús G. García Torres +5 more
doaj +1 more source
The Azide-Allene Dipolar Cycloaddition: Is DFT Able to Predict Site- and Regio-Selectivity?
Molecules, 2021 The site- and regio-selectivity of thermal, uncatalysed 1,3-dipolar cycloadditions between arylazides and mono- or tetra-substituted allenes with different electronic features have been investigated by both conceptual (reactivity indices) and ...
Giorgio Molteni, Alessandro Ponti
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Sodium azide poisoning: a narrative review
Clinical toxicology, 2021 Context Sodium azide is a highly toxic chemical. Its production has increased dramatically over the last 30 years due to its widespread use in vehicular airbags, and it is available for purchase online.
J. Tat +5 more
semanticscholar +1 more source
Molecules, 2022 Our investigation includes the synthesis of new naphthalene-bis-triazole-bis-quinolin-2(1H)-ones 4a–e and 7a–e via Cu-catalyzed [3 + 2] cycloadditions of 4-azidoquinolin-2(1H)-ones 3a–e with 1,5-/or 1,8-bis(prop-2-yn-1-yloxy)naphthalene (2) or (6).
Essmat M. El-Sheref +12 more
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HUISGEN AND HIS ADVENTURES IN A PLAYGROUND OF MECHANISMS AND NOVEL REACTIONS [PDF]
Química Nova, 2021 The death of professor Rolf Huisgen (1920-2020) was announced on March 26th 2020, in the midst of the COVID-19 pandemic. Professor Huisgen was professor emeritus at the University of Munich in Germany, and studied in detail the mechanism of the 1,3 ...
Daniel T. G. Gonzaga +5 more
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