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ABR Features in Ski-Slope Hearing Loss for Hearing Threshold Estimation: A Comparative Clinical Study of Click and CE-Chirp Stimuli [PDF]
ChildrenBackground: Auditory brainstem responses (ABRs) are widely used for objective hearing threshold estimation in both adults and children. Click and CE-Chirp stimuli differ substantially in cochlear activation and neural synchrony, yet their relative ...
Davide Brotto +7 more
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PharmaceuticsIn this study, three new 3,7-dihydroxyflavone (1) derivatives with different sugars were designed and synthesised by click chemistry. Click chemistry requires the previously modification of building blocks with azide and alkyne groups and therefore, the ...
Nuno M. Saraiva +6 more
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Frontiers in Digital Health, 2022 Digital therapeutics (DTx) are software programs that treat a disease or condition. Increasingly, DTx are part of medical care, and in the US healthcare system they are regulated by the FDA as Software as a Medical Device (SaMD).
Jacqueline Lutz +6 more
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Preparing Children for an Unpredictable World in the Middle of a Crisis: La Aldea's Approach
Journal on Education in Emergencies, 2023 No one was prepared when COVID-19 hit. While education systems all over the world turned to distance learning, countries like Colombia faced a significant challenge: only 75 percent of Colombian teachers had received training in online teaching, 64 ...
Ana María Restrepo-Sáenz +1 more
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Journal of Lipid Research, 2022 Fatty acid beta-oxidation is a key process in mammalian lipid catabolism. Disturbance of this process results in severe clinical symptoms, including dysfunction of the liver, a major beta-oxidizing tissue.
Lars Kuerschner +5 more
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Tracing Lipid Metabolism by Alkyne Lipids and Mass Spectrometry: The State of the Art
Frontiers in Molecular Biosciences, 2022 Lipid tracing studies are a key method to gain a better understanding of the complex metabolic network lipids are involved in. In recent years, alkyne lipid tracers and mass spectrometry have been developed as powerful tools for such studies.
Lars Kuerschner, Christoph Thiele
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Biocompatible nanoreactors of catalase and nanozymes for anticancer therapeutics
Nano Select, 2021 Significant progress has laid the groundwork in understanding the fundamental role of catalase enzyme and catalase‐like nanozymes, notably with the emergence of nano‐bioreactors which are promoting nanomaterials‐based antitumor therapeutic strategies ...
Tanya Munjal, Saikat Dutta
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Chemical Society Reviews, 2010 The development of new polymerization reactions is of critical importance to macromolecule science. In this critical review, we summarize the research efforts to incubate alkyne-azide click reactions into a versatile polymerization technique for the synthesis of poly(triazole)s (PTAs) with linear and hyperbranched structures.
Qin, Anjun +2 more
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Molecules, 2021 A mild and versatile method based on Cu-catalyzed [2+3] cycloaddition (Huisgen-Meldal-Sharpless reaction) was developed to tether 3,3’-((4-(prop-2-yn-1-yloxy)phenyl)methylene)bis(4-hydroxyquinolin-2(1H)-ones) with 4-azido-2-quinolones in good yields ...
Essmat M. El-Sheref +6 more
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Advanced Materials Interfaces, 2023 2D materials have attracted considerable attention in the past decade for their superlative physical properties. Lightweight foam from 2D materials can reduce the use of raw materials, save energy in processing the material and downregulate the carbon ...
Rahul Patil, Saikat Dutta
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