Results 31 to 40 of about 1,975,807 (282)

Recent Advances in Click Chemistry Applied to Dendrimer Synthesis

Molecules, 2015
Dendrimers are monodisperse polymers grown in a fractal manner from a central point. They are poised to become the cornerstone of nanoscale devices in several fields, ranging from biomedicine to light-harvesting. Technical difficulties in obtaining these
Mathieu Arseneault, Caroline Wafer, Jean-François Morin   +2 more
doaj   +1 more source

Biotin-Conjugated Cellulose Nanofibers Prepared via Copper-Catalyzed Alkyne-Azide Cycloaddition (CuAAC) “Click” Chemistry

Nanomaterials, 2020
As potential high surface area for selective capture in diagnostic or filtration devices, biotin-cellulose nanofiber membranes were fabricated to demonstrate the potential for specific and bio-orthogonal attachment of biomolecules onto nanofiber surfaces.
Katarina Goodge, Margaret Frey
doaj   +1 more source

Unbiased Learning to Rank with Unbiased Propensity Estimation

, 2018
Learning to rank with biased click data is a well-known challenge. A variety of methods has been explored to debias click data for learning to rank such as click models, result interleaving and, more recently, the unbiased learning-to-rank framework ...
Ai, Qingyao, Bi, Keping, Croft, W. Bruce, Guo, Jiafeng, Luo, Cheng   +4 more
core   +1 more source

Processing of Paired Click-Tone Stimulation in the Mice Inferior Colliculus

Frontiers in Physiology, 2019
The inferior colliculus (IC) is known as a neuronal structure involved in the integration of acoustic information in the ascending auditory pathway. However, the processing of paired acoustic stimuli containing different sound types, especially when they
Ningqian Wang, Minlin Lin, An Qiao, Zhongju Xiao   +3 more
doaj   +1 more source

Recent Advances in Transition Metal-Catalyzed Ring-Opening Reaction of Aziridine

Compounds
The smallest strained, saturated N-heterocycles, such as aziridine, can be a valuable building block in synthetic organic chemistry. Ring-opening reactions with various nucleophiles could be the most important strategy to synthesize various value-added ...
Partha Sarathi Bera, Yafia Kousin Mirza, Tarunika Sachdeva, Milan Bera   +3 more
doaj   +1 more source

Contralateral inhibition of click- and chirp-evoked human compound action potentials [PDF]

, 2017
Cochlear outer hair cells (OHC) receive direct efferent feedback from the caudal auditory brainstem via the medial olivocochlear (MOC) bundle. This circuit provides the neural substrate for the MOC reflex, which inhibits cochlear amplifier gain and is ...
Cone, Barbara K, Lichtenhan, Jeffery T, Smith, Spencer B   +2 more
core   +2 more sources

Feasibility of a digital therapeutic for experiential negative symptoms of schizophrenia: results from an exploratory study

Schizophrenia
Experiential negative symptoms (ENS) of schizophrenia, such as asociality, anhedonia, and avolition, are associated with poor outcomes, yet no FDA-approved pharmacotherapies currently exist specifically to target these symptoms.
Haig Goenjian, Abhishek Pratap, Cassandra Snipes, Brendan D. Hare, Joshua T. Kantrowitz, Tshekedi Dennis, Wakelin McNeel, Eehwa Ung, Olya Besedina, Alankar Gupta, Tim Campellone, Mariya Petrova, Sergio Perocco, Uma Vaidyanathan, Shaheen E. Lakhan, Cornelia Dorner-Ciossek   +15 more
doaj   +1 more source

A comparison of commercially available auditory brainstem response stimuli at a neurodiagnostic intensity level

Audiology Research, 2017
iChirp-evoked auditory brainstem responses (ABRs) yield a larger wave V amplitude at low intensity levels than traditional broadband click stimuli, providing a reliable estimation of hearing sensitivity.
Devan A. Keesling, Jordan Paige Parker, Jason Tait Sanchez   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

An Assessment of the Scholarship of Teaching and Learning in Public Administration from 2009-2013 [PDF]

InSight, 2016
The acceptance of the Scholarship of Teaching and Learning (SoTL) as a legitimate form of scholarly investigation and the shape that it takes in post-secondary education are inherently discipline-specific.
Rebekkah Stuteville, Eric Click
doaj   +2 more sources