Results 31 to 40 of about 1,402,473 (296)

To Click or Not To Click

Proceedings of the 25th ACM International on Conference on Information and Knowledge Management, 2016
Thumbnails play such an important role in online videos. As the most representative snapshot, they capture the essence of a video and provide the first impression to the viewers; ultimately, a great thumbnail makes a video more attractive to click and watch.
Yale Song, Miriam Redi, Jordi Vallmitjana, Alejandro Jaimes   +3 more
openaire   +2 more sources

Advances in Green and Sustainable Photo Redox Catalysis for Organic Transformation

Innovation of Chemistry & Materials for Sustainability
Advances in visible-light-mediated photo redox catalysis have created an exceptional approach for small-molecule activation and new chemical bond formation in organic synthesis. This is an alternative technique to generate new reactive intermediates and
Yafia Kousin Mirza, Partha Sarathi Bera, Ajeet Kumar Pandey, Prof. Bera Milan   +3 more
doaj   +1 more source

Click to learn, learn to click: Undergraduate Synthetic Organic Chemistry experiments [PDF]

, 2022
The optimization of an undergraduate experiment for Organic Chemistry students is described to explore the concept of click chemistry. The preparation of a terminal fluorescent alkyne and an organic azide is reported consisting of simple steps. These are
Francisco, Santoyo-Gonzalez, Alejandro, Lopez-Ruiz, Alicia, Megia-Fernandez, Mariano, Ortega-Muñoz   +3 more
core   +2 more sources

Integrated analysis of two randomized controlled trials of a digital therapeutic for episodic migraine prevention

npj Digital Medicine
Migraine is a highly disabling neurological condition that requires effective preventive treatment options. We developed CT-132, a digital therapeutic that delivers clinically validated cognitive behavioral therapeutic interventions, as an adjunct to ...
Shaheen E. Lakhan, Mariya Petrova, Cassandra Snipes, Alexander Kuka, Timothy Peters-Strickland, Olya Besedina, Laura Taraboanta, Viveca Livezey, Austin Speier, Merle Diamond, Stewart J. Tepper   +10 more
doaj   +1 more source

Perception of non-native click consonant contrasts : implications for theories of speech perception

, 2020
Perception of click consonants and discrimination of click contrasts by non-native listeners differs depending on whether their native language does or does not employ clicks. Listeners of non-click languages generally perceive click bursts as non-speech
Best, Catherine T. (R11322)
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Click-based synthesis and proteomic profiling of lipstatin analogues

, 2010
Using click chemistry to enable both structural diversity and proteome profiling within a natural product derived library, two out of nineteen lipstatin analogues showed similar activity to Orlistat against fatty acid synthase (FAS), but with an improved
Mun H. Ngai (17192422), Markus R. Wenk (136744), Martin Lear (17161933), Yuan Shen (194742), Kai Liu (159026), Peng-Yu Yang (1319298), Shao Q. Yao (1525546)   +6 more
core   +5 more sources

Feasibility of a digital therapeutic for experiential negative symptoms of schizophrenia: results from an exploratory study

Schizophrenia
Experiential negative symptoms (ENS) of schizophrenia, such as asociality, anhedonia, and avolition, are associated with poor outcomes, yet no FDA-approved pharmacotherapies currently exist specifically to target these symptoms.
Haig Goenjian, Abhishek Pratap, Cassandra Snipes, Brendan D. Hare, Joshua T. Kantrowitz, Tshekedi Dennis, Wakelin McNeel, Eehwa Ung, Olya Besedina, Alankar Gupta, Tim Campellone, Mariya Petrova, Sergio Perocco, Uma Vaidyanathan, Shaheen E. Lakhan, Cornelia Dorner-Ciossek   +15 more
doaj   +1 more source

Recent Advances in Transition Metal-Catalyzed Ring-Opening Reaction of Aziridine

Compounds
The smallest strained, saturated N-heterocycles, such as aziridine, can be a valuable building block in synthetic organic chemistry. Ring-opening reactions with various nucleophiles could be the most important strategy to synthesize various value-added ...
Partha Sarathi Bera, Yafia Kousin Mirza, Tarunika Sachdeva, Milan Bera   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source