Results 21 to 30 of about 210,123 (350)

New catalytic strategies for DNA and RNA alkylation using rhodium (II) and copper (I) carbenes - a versatile tool for applications in chemical biology [PDF]

, 2015
A variety of nucleic acid substrates were catalytically alkylated with rhodium(II) and copper(I)-carbenoids generated from diazocarbonyl compounds. The alkylation took place via an N-H insertion reaction selectively targeting the nucleobases in single ...
Tishinov, Kiril
core   +1 more source

Oligonucleotide Tagging for Copper-Free Click Conjugation

Molecules, 2013
Copper-free click chemistry between cyclooctynes and azide is a mild, fast and selective technology for conjugation of oligonucleotides. However, technology for site-specific introduction of the requisite probes by automated protocols is scarce, while ...
Alan Rowan, Floris L. van Delft, John C. Hodges, Nancy S. Barta, Brian Gibson, Anup M. Jawalekar, Jorge M. M. Verkade, Sudip Malik   +7 more
doaj   +1 more source

Practical Considerations, Challenges, and Limitations of Bioconjugation via Azide-Alkyne Cycloaddition

Bioconjugate chemistry, 2017
Interrogating biological systems is often limited by access to biological probes. The emergence of “click chemistry” has revolutionized bioconjugate chemistry by providing facile reaction conditions amenable to both biologic molecules and small molecule ...
Chad J. Pickens, Stephanie N. Johnson, Melissa M. Pressnall, Martin A. Leon, C. Berkland   +4 more
semanticscholar   +1 more source

Chemical Architecture and Applications of Nucleic Acid Derivatives Containing 1,2,3-Triazole Functionalities Synthesized via Click Chemistry

Molecules, 2012
There is considerable attention directed at chemically modifying nucleic acids with robust functional groups in order to alter their properties. Since the breakthrough of copper-assisted azide-alkyne cycloadditions (CuAAC), there have been several ...
Wei Gong, Tim Efthymiou, Jean-Paul Desaulniers   +2 more
doaj   +1 more source

Stereochemical Geometries and Photoluminescence in Pseudo-Halido-Zinc(II) Complexes. Structural Comparison between the Corresponding Cadmium(II) Analogs

Inorganics, 2021
Six pseudohalide zinc(II) containing a variety of N-donor auxiliary amines were structurally characterized. These include two mononuclear trigonal bipyramidal [Zn(NTB)(N3)]ClO4·½H2O (3) and [Zn(TPA)(NCS)]ClO4 (4), two distorted octahedral [Zn(1,8-damnph ...
Franz A. Mautner, Roland C. Fischer, Ana Torvisco, Nahed M. H. Salem, Amber R. Dugas, Shelby F. Aaron, Sushant P. Sahu, Febee R. Louka, Salah S. Massoud   +8 more
doaj   +1 more source

Review of novel energetic polymers and binders – high energy propellant ingredients for the new space race

Designed Monomers and Polymers, 2019
Current solid rocket propellant formulations still employ traditional ingredients utilized since the 1960s, such as hydroxyl terminated polybutadiene (HTPB).
Tianze Cheng
doaj   +1 more source

2-(2-Azabicyclo[3.2.1]octa-3,6-dien-2-yl)-1,3-dimethoxyimidazolium hexafluoridophosphate

IUCrData, 2016
The title salt, C12H16N3O2+·PF6−, was obtained by the dipolar cycloaddition of norbornadiene to 2-azido-1,3-dimethoxyimidazolium hexafluoridophosphate.
Simone Haslinger, Gerhard Laus, Klaus Wurst, Herwig Schottenberger   +3 more
doaj   +1 more source

Crystal structures of 4-{(E)-3-[(imino-λ5-azanylidene)amino]prop-1-enyl}-N,N-dimethylimidazole-1-sulfonamide and 2-[(imino-λ5-azanylidene)amino]-4-{(E)-3-[(imino-λ5-azanylidene)amino]prop-1-enyl}-N,N-dimethylimidazole-1-sulfonamide

Acta Crystallographica Section E: Crystallographic Communications, 2019
The structures of two azide containing imidazole derivatives are reported. Allylic azides are fairly reactive making them attractive starting compounds to convert into amides.
Lorenzo M. Cruz, Raakiyah Y. Moore, Marcela Torres Gutierrez, Apsara K. Herath, Carl J. Lovely, Muhammed Yousufuddin   +5 more
doaj   +1 more source

Crystal structure of (N^C) cyclometalated AuIII diazide at 100 K

Acta Crystallographica Section E: Crystallographic Communications, 2020
The title compound, an (N^C)-cyclometalated gold(III) diazide, namely, diazido[5-ethoxycarbonyl-2-(5-ethoxycarbonylpyridin-2-yl)phenyl-κ2C1,N]gold(III), [Au(C17H16NO4)(N3)2] or Au(ppyEt)(N3)2, was synthesized by reacting Au(ppyEt)Cl2 with NaN3 in water ...
Volodymyr Levchenko, Sigurd Øien-Ødegaard, David Wragg, Mats Tilset   +3 more
doaj   +1 more source

Synthesis of Calix[4]arene Appended Lactosylated G1 and Galacto­sylated G2 Generation Glycodendrimers using a ‘CuAAC’ Click Approach

SynOpen, 2023
A modular and highly reliable click approach is applied for the expeditious synthesis of lactose- and galactose-coated calixarene-cored G1 and G2 generation glycodendrimers, respectively.
Sunil Kumar, Mangal S. Yadav, Sumit K. Singh, Sanchayita Rajkhowa, Vinod K. Tiwari   +4 more
doaj   +1 more source