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Overview of 1,5-Selective Click Reaction of Azides with Alkynes or Their Synthetic Equivalents [PDF]
Molecules, 2023 Nowadays, the click reaction of azides with alkynes has evolved rapidly and become one of the most efficient methods to synthesize 1,2,3-triazoles, which are an important class of N-containing heterocycles.
Wen-Xiong Zhang
exaly +5 more sources
Salt Metathesis: An Ultimate Click Reaction [PDF]
Precision ChemistryIn this Comment, we suggest salt metathesis (or ion exchange) as an ultimate click reaction, extending click chemistry principles beyond covalent bonds to ionic interactions. These universal and robust reactions, which nature utilizes in marine organisms' biomineralization processes, proceed spontaneously under mild conditions with minimal waste ...
Christopher M. Butch +2 more
doaj +4 more sources
Photo Click Reaction of Acylsilanes with Indoles. [PDF]
Angew Chem Int Ed Engl, 2021 AbstractLight‐mediated coupling of acylsilanes with indoles is reported. This photo click reaction occurs under mild conditions (415 nm) mostly in quantitative yield and provides stable silylated N,O‐acetals via light mediated siloxycarbene generation with subsequent indole‐N‐H insertion.
Stuckhardt C, Wissing M, Studer A.
europepmc +5 more sources
CBT‐Cys click reaction for optical bioimaging in vivo
View, 2023 Derived from the D‐luciferin regeneration pathway in firefly body, the click condensation reaction between 2‐cyanobenzothiazole (CBT) and D‐cysteine (Cys) (CBT‐Cys click reaction) possesses unique advantages, including superior biocompatibility, high ...
Runqun Tang +5 more
core +2 more sources
Chem. Soc. Rev., 2010 Fluorogenic Cu(I)-catalyzed alkyne-azide cycloaddition (CuAAC) reactions have emerged as a powerful tool for bioconjugation, materials science, organic synthesis and drug discovery.
Wang, Chao +3 more
core +3 more sources
Post-Functionalization of Organometallic Complexes via Click-Reaction [PDF]
Molecules, 2022 CuAAC (Cu catalyzed azide-alkyne cycloaddition) click-reaction is a simple and powerful method for the post-synthetic modification of organometallic complexes of transition metals. This approach allows the selective introduction of additional donor sites
Stanislav Petrovskii +4 more
doaj +2 more sources
The sulfo-click reaction and dual labeling of nucleosides [PDF]
Current Protocols in Nucleic Acid Chemistry, 2020 International audienceThis unit contains detailed synthetic procedures for the implementation of the sulfo-click reaction to nucleoside derivatives. First, 3'-O-TBDMS-protected nucleosides are converted to their corresponding 4'-thioacide derivatives in ...
Guillaume Clavé +5 more
core +3 more sources
Application of a Double Aza-Michael Reaction in a ‘Click, Click, Cy-Click’ Strategy: From Bench to Flow [PDF]
Synthesis, 2011 The development of a ‘click, click, cy-click’ process utilizing a double aza-Michael reaction to generate functionalized 1,2,5-thiadiazepane 1,1-dioxides is reported.
Zhou, Aihua +17 more
core +5 more sources
Conformation of G-quadruplex Controlled by Click Reaction
Molecules, 2020 G-quadruplexes are non-canonical four stranded secondary structures possessing great biological importance. Controlling G-quadruplex conformation for further regulating biological processes is both exciting and challenging.
Chuan-Xin Guo +4 more
core +2 more sources
Facile fabrication of polymer network using click chemistry and their computational study [PDF]
Royal Society Open Science, 2021 Click reaction is a very fast, high yield with no by-product, biocompatible, tolerant to surrounded medium, and very specific cycloaddition reaction between azides and alkynes to form triazole.
Md. Kausar Ahmed +2 more
doaj +1 more source