Results 31 to 40 of about 2,796,861 (304)
Molecules, 2018 Two conjugation methods using different linkers were applied for the investigation of the spectral characteristics and activity of G-quadruplex (G4)–hemin conjugates.
Joanna Kosman +2 more
doaj +1 more source
Origin of Orthogonality of Strain‐Promoted Click Reactions [PDF]
Chemistry – A European Journal, 2015 AbstractSite‐specific labeling of biomolecules is rapidly advancing due to the discovery of novel mutually orthogonal reactions. Quantum chemistry studies have also increased our understanding of their relative rates, although these have until now been based on highly simplified reactants.
Wagner Johannes A. +4 more
openaire +4 more sources
Exploration of Optical Properties of Novel Pyrene Derivatives Modified by Click Functionalization
Crystals, 2022 A simple synthetic method was designed, in which the Sonogashira coupling reaction and [2+2] cycloaddition click reaction with high yield were performed on 1-bromopyrene to obtain several novel pyrene derivatives.
Yang Yu +7 more
doaj +1 more source
“Click” reactions in polysaccharide modification [PDF]
Progress in Polymer Science, 2016 Abstract Polysaccharide chemistry is enjoying accelerating development thanks to advances in synthetic techniques, biochemistry and solvents, which enable polysaccharide materials to be useful in a variety of demanding applications. Among the synthetic advances, click chemistry has reconfigured the realm of polysaccharide modification that previously
Xiangtao Meng, Kevin J. Edgar
openaire +1 more source
Click-Ready Perfluorocarbon Nanoemulsion for 19F MRI and Multimodal Cellular Detection
, 2021 We describe an in vivo imaging probe platform that is readily modifiable to accommodate binding of different molecular targeting moieties and payloads for multimodal image generation.
Eric T. Ahrens +15 more
core +1 more source
Phosphorus(V) Fluoride Exchange (PFEx): Multidimensional Click Chemistry from Phosphorus(V) Connective Hubs [PDF]
, 2022 We report catalytic Phosphorus Fluoride Exchange (PFEx) as the latest advance in connective click-reaction technology. Emulating Nature, PFEx reaches into the biological world and creates stable tetrahedral P(V)- connections through efficient phosphorus ...
Shoujun, Sun +5 more
core +2 more sources
Click-Ready Perfluorocarbon Nanoemulsion for 19F MRI and Multimodal Cellular Detection
, 2021 We describe an in vivo imaging probe platform that is readily modifiable to accommodate binding of different molecular targeting moieties and payloads for multimodal image generation.
Hongyan Xu (29047) +7 more
core +1 more source
Click histochemistry for whole-mount staining of brain structures
MethodsX, 2019 Labeling of the replicating DNA with synthetic thymidine analogs is commonly used for marking the dividing cells. However, until now this method has only been applied to histological sections.
Alexander A. Lazutkin +2 more
doaj +1 more source
A dark intermediate in the fluorogenic reaction between tetrazine fluorophores and trans-cyclooctene
Biophysical Reports, 2022 Fluorogenic labeling via bioorthogonal tetrazine chemistry has proven to be highly successful in fluorescence microscopy of living cells. To date, trans-cyclooctene (TCO) and bicyclonyne have been found to be the most useful substrates for live-cell ...
Felix Hild +4 more
doaj +1 more source
Conformation of G-quadruplex Controlled by Click Reaction
Molecules, 2020 G-quadruplexes are non-canonical four stranded secondary structures possessing great biological importance. Controlling G-quadruplex conformation for further regulating biological processes is both exciting and challenging.
Chao-Da Xiao +4 more
doaj +1 more source