Conformation of G-quadruplex Controlled by Click Reaction
Molecules, 2020 G-quadruplexes are non-canonical four stranded secondary structures possessing great biological importance. Controlling G-quadruplex conformation for further regulating biological processes is both exciting and challenging.
Chao-Da Xiao +4 more
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Pharmaceuticals, 2023 The innovative design of a triarylborane (TB)-dye with one NMe2-alkylated (propargylated) group and one NMe2 group yielded a system that is both an NMe2 π-donor and an inductive NMe2-alkyl cationic acceptor.
Marta Jurković +4 more
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Facile synthesis of cooperative acid-base catalysts by clicking cysteine and cysteamine on an ethylene-bridged periodic mesoporous organosilica [PDF]
, 2016 A periodic mesoporous organosilica (PMO) that contains ethylene bridges was functionalized to obtain a series of cooperative acid-base catalysts. A straightforward, single-step procedure was devised to immobilize cysteine and cysteamine on the support ...
Esquivel Merino, Maria Dolores +6 more
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Click histochemistry for whole-mount staining of brain structures
MethodsX, 2019 Labeling of the replicating DNA with synthetic thymidine analogs is commonly used for marking the dividing cells. However, until now this method has only been applied to histological sections.
Alexander A. Lazutkin +2 more
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Dynamic pore-scale reservoir-condition imaging of reaction in carbonates using synchrotron fast tomography [PDF]
, 2015 Synchrotron fast tomography was used to dynamically image dissolution of limestone in the presence of CO2-saturated brine at reservoir conditions. 100 scans were taken at a 6.1 µm resolution over a period of 2 hours.
Andrew, MG +3 more
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Click-to-Chelate: Development of Technetium and Rhenium-Tricarbonyl Labeled Radiopharmaceuticals
Molecules, 2013 The Click-to-Chelate approach is a highly efficient strategy for the radiolabeling of molecules of medicinal interest with technetium and rhenium-tricarbonyl cores.
Thomas L. Mindt, Christiane A. Kluba
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Extended π-conjugated pyrene derivatives: structural, photophysical and electrochemical properties [PDF]
, 2016 This article presents a set of extended π-conjugated pyrene derivatives, namely 1,3-di(arylethynyl)-7-tert-butylpyrenes, which were synthesized by a Pd-catalyzed Sonogashira coupling reaction of 1,3-dibromo-7-tert-butylpyrenes with the corresponding ...
Bordeau +42 more
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“Click” reactions in polysaccharide modification [PDF]
Progress in Polymer Science, 2016 Abstract Polysaccharide chemistry is enjoying accelerating development thanks to advances in synthetic techniques, biochemistry and solvents, which enable polysaccharide materials to be useful in a variety of demanding applications. Among the synthetic advances, click chemistry has reconfigured the realm of polysaccharide modification that previously
Xiangtao Meng, Kevin J. Edgar
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Cymantrene–Triazole "Click" Products: Structural Characterization and Electrochemical Properties [PDF]
, 2014 We report the first known examples of triazole-derivatized cymantrene complexes (η5-[4-substituted triazol-1-yl]cyclopentadienyl)tricarbonylmanganese(I), obtained via a “click” chemical synthesis, bearing a phenyl, 3-aminophenyl, or 4-aminophenyl moiety ...
Abboud J.-L. M. +59 more
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Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]
, 2017 Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin +7 more
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