Exploration of Optical Properties of Novel Pyrene Derivatives Modified by Click Functionalization
A simple synthetic method was designed, in which the Sonogashira coupling reaction and [2+2] cycloaddition click reaction with high yield were performed on 1-bromopyrene to obtain several novel pyrene derivatives.
Yang Yu +7 more
doaj +1 more source
Click-Ready Perfluorocarbon Nanoemulsion for 19F MRI and Multimodal Cellular Detection
We describe an in vivo imaging probe platform that is readily modifiable to accommodate binding of different molecular targeting moieties and payloads for multimodal image generation.
Eric T. Ahrens +15 more
core +1 more source
“Click” reactions in polysaccharide modification [PDF]
Abstract Polysaccharide chemistry is enjoying accelerating development thanks to advances in synthetic techniques, biochemistry and solvents, which enable polysaccharide materials to be useful in a variety of demanding applications. Among the synthetic advances, click chemistry has reconfigured the realm of polysaccharide modification that previously
Xiangtao Meng, Kevin J. Edgar
openaire +1 more source
Click-Ready Perfluorocarbon Nanoemulsion for 19F MRI and Multimodal Cellular Detection
We describe an in vivo imaging probe platform that is readily modifiable to accommodate binding of different molecular targeting moieties and payloads for multimodal image generation.
Hongyan Xu (29047) +7 more
core +1 more source
Click histochemistry for whole-mount staining of brain structures
Labeling of the replicating DNA with synthetic thymidine analogs is commonly used for marking the dividing cells. However, until now this method has only been applied to histological sections.
Alexander A. Lazutkin +2 more
doaj +1 more source
A dark intermediate in the fluorogenic reaction between tetrazine fluorophores and trans-cyclooctene
Fluorogenic labeling via bioorthogonal tetrazine chemistry has proven to be highly successful in fluorescence microscopy of living cells. To date, trans-cyclooctene (TCO) and bicyclonyne have been found to be the most useful substrates for live-cell ...
Felix Hild +4 more
doaj +1 more source
Conformation of G-quadruplex Controlled by Click Reaction
G-quadruplexes are non-canonical four stranded secondary structures possessing great biological importance. Controlling G-quadruplex conformation for further regulating biological processes is both exciting and challenging.
Chao-Da Xiao +4 more
doaj +1 more source
The innovative design of a triarylborane (TB)-dye with one NMe2-alkylated (propargylated) group and one NMe2 group yielded a system that is both an NMe2 π-donor and an inductive NMe2-alkyl cationic acceptor.
Marta Jurković +4 more
doaj +1 more source
Biologically targeted probes for Zn2+: a diversity oriented modular “click-SNAr-click” approach [PDF]
We describe a one-pot strategy for the high yielding, operationally simple synthesis of fluorescent probes for Zn2+ that bear biological targeting groups and exemplify the utility of our method through the preparation of a small library of sensors ...
Hodson, D.J. +15 more
core +1 more source
Click-to-Chelate: Development of Technetium and Rhenium-Tricarbonyl Labeled Radiopharmaceuticals
The Click-to-Chelate approach is a highly efficient strategy for the radiolabeling of molecules of medicinal interest with technetium and rhenium-tricarbonyl cores.
Thomas L. Mindt, Christiane A. Kluba
doaj +1 more source

