Results 11 to 20 of about 2,796,861 (304)
Application of a Double Aza-Michael Reaction in a ‘Click, Click, Cy-Click’ Strategy: From Bench to Flow [PDF]
Synthesis, 2011 The development of a 'click, click, cy-click' process utilizing a double aza-Michael reaction to generate functionalized 1,2,5-thiadiazepane 1,1-dioxides is reported. Optimization in flow, followed by scale out of the inter-/intramolecular double aza-Michael addition has also been realized using a microwave-assisted, continuous flow organic synthesis ...
Zang, Qin +8 more
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The Sulfo‐Click Reaction and Dual Labeling of Nucleosides [PDF]
Current Protocols in Nucleic Acid Chemistry, 2020 AbstractThis article contains detailed synthetic procedures for the implementation of the sulfo‐click reaction to nucleoside derivatives. First, 3′‐O‐TBDMS‐protected nucleosides are converted to their corresponding 4′‐thioacid derivatives in three steps.
Guillaume, Clavé +2 more
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RAFT-Based Polymers for Click Reactions [PDF]
Polymers, 2022 The parallel development of reversible deactivation radical polymerization and click reaction concepts significantly enriches the toolbox of synthetic polymer chemistry. The synergistic effect of combining these approaches manifests itself in a growth of interest to the design of well-defined functional polymers and their controlled conjugation with ...
Elena V. Chernikova +1 more
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The Carbodiimide Click Reaction Provides Rapid and Conver-gent Access to Aminotriazoloquinazolines [PDF]
, 2022 A novel, convergent synthesis of aminotriazoloquinazolines is reported. These heterocycles are reliably prepared via a “click” reaction between readily available aryl carbodiimides and acyl hydrazides.
Aaron, Sather +7 more
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Linking Chemical Reaction Intermediates of the Click Reaction to Their Molecular Diffusivity [PDF]
, 2021 Bipolar reactions have been provoked by reports of boosted diffusion during chemical and enzymatic reactions. To some, it is intuitively reasonable that relaxation to truly Brownian motion after passing an activation barrier can be slow, but to others ...
Tian, Huang +3 more
core +1 more source
Photo Click Reaction of Acylsilanes with Indoles. [PDF]
Angew Chem Int Ed Engl, 2021 AbstractLight‐mediated coupling of acylsilanes with indoles is reported. This photo click reaction occurs under mild conditions (415 nm) mostly in quantitative yield and provides stable silylated N,O‐acetals via light mediated siloxycarbene generation with subsequent indole‐N‐H insertion.
Stuckhardt C, Wissing M, Studer A.
europepmc +5 more sources
Response to Comment on “Following molecular mobility during chemical reactions: no evidence for active propulsion” and “Molecular diffusivity of click reaction components: the diffusion enhancement question” [PDF]
, 2022 In their Comment (Huang, T.; Granick, S. ChemRxiv 2022) on two related publications (J. Am. Chem. Soc. 2021, 143, 20884-20890; J. Am. Chem. Soc. 2022, 144, 1380-1388), Huang et al.
Jaime, Agudo-Canalejo +7 more
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Synthesis of Terpolymers by Click Reactions [PDF]
Chemistry – An Asian Journal, 2011 AbstractWell‐defined polymeric structures were easily generated through living polymerization systems, in particular, living radical polymerizations. The polymeric precursors with orthogonal functionalities were subsequently clicked together with single or double (combinatorial) click reactions, such as the copper‐catalyzed azide–alkyne cycloadditions (
Ozcan, Altintas, Umit, Tunca
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Quantitation of deoxynucleoside triphosphates by click reactions [PDF]
Scientific Reports, 2020 AbstractThe levels of the four deoxynucleoside triphosphates (dNTPs) are under strict control in the cell, as improper or imbalanced dNTP pools may lead to growth defects and oncogenesis. Upon treatment of cancer cells with therapeutic agents, changes in the canonical dNTPs levels may provide critical information for evaluating drug response and mode ...
Huan, C. Y. +3 more
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Organotitanium Click Chemistry [PDF]
, 2023 The click chemistry of titanium exemplified by the “green” [3+2] cycloaddition of the [Ti-N3] moiety with nitriles RCN to form a tetrazole ligand, is currently limited in scope, but the future of this open and wide field is bright, full of promising ...
Gregory, Arzoumanidis +1 more
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