Results 11 to 20 of about 2,673,237 (301)
Fluorogenic Cu(I)-catalyzed alkyne-azide cycloaddition (CuAAC) reactions have emerged as a powerful tool for bioconjugation, materials science, organic synthesis and drug discovery.
Wang, Chao +3 more
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The sulfo-click reaction and dual labeling of nucleosides [PDF]
International audienceThis unit contains detailed synthetic procedures for the implementation of the sulfo-click reaction to nucleoside derivatives. First, 3'-O-TBDMS-protected nucleosides are converted to their corresponding 4'-thioacide derivatives in ...
Guillaume Clavé +5 more
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RAFT-Based Polymers for Click Reactions [PDF]
The parallel development of reversible deactivation radical polymerization and click reaction concepts significantly enriches the toolbox of synthetic polymer chemistry. The synergistic effect of combining these approaches manifests itself in a growth of interest to the design of well-defined functional polymers and their controlled conjugation with ...
Elena V. Chernikova +1 more
openaire +2 more sources
Linking Chemical Reaction Intermediates of the Click Reaction to Their Molecular Diffusivity [PDF]
Bipolar reactions have been provoked by reports of boosted diffusion during chemical and enzymatic reactions. To some, it is intuitively reasonable that relaxation to truly Brownian motion after passing an activation barrier can be slow, but to others ...
Tian, Huang +3 more
core +1 more source
Photo Click Reaction of Acylsilanes with Indoles. [PDF]
AbstractLight‐mediated coupling of acylsilanes with indoles is reported. This photo click reaction occurs under mild conditions (415 nm) mostly in quantitative yield and provides stable silylated N,O‐acetals via light mediated siloxycarbene generation with subsequent indole‐N‐H insertion.
Stuckhardt C, Wissing M, Studer A.
europepmc +5 more sources
The Carbodiimide Click Reaction Provides Rapid and Conver-gent Access to Aminotriazoloquinazolines [PDF]
A novel, convergent synthesis of aminotriazoloquinazolines is reported. These heterocycles are reliably prepared via a “click” reaction between readily available aryl carbodiimides and acyl hydrazides.
Aaron, Sather +3 more
core +2 more sources
Organotitanium Click Chemistry [PDF]
The click chemistry of titanium exemplified by the “green” [3+2] cycloaddition of the [Ti-N3] moiety with nitriles RCN to form a tetrazole ligand, is currently limited in scope, but the future of this open and wide field is bright, full of promising ...
Gregory, Arzoumanidis
core +1 more source
Synthesis of Terpolymers by Click Reactions [PDF]
AbstractWell‐defined polymeric structures were easily generated through living polymerization systems, in particular, living radical polymerizations. The polymeric precursors with orthogonal functionalities were subsequently clicked together with single or double (combinatorial) click reactions, such as the copper‐catalyzed azide–alkyne cycloadditions (
Ozcan, Altintas, Umit, Tunca
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Response to Comment on “Following molecular mobility during chemical reactions: no evidence for active propulsion” and “Molecular diffusivity of click reaction components: the diffusion enhancement question” [PDF]
In their Comment (Huang, T.; Granick, S. ChemRxiv 2022) on two related publications (J. Am. Chem. Soc. 2021, 143, 20884-20890; J. Am. Chem. Soc. 2022, 144, 1380-1388), Huang et al.
Jaime, Agudo-Canalejo +3 more
core +1 more source
Quantitation of deoxynucleoside triphosphates by click reactions [PDF]
AbstractThe levels of the four deoxynucleoside triphosphates (dNTPs) are under strict control in the cell, as improper or imbalanced dNTP pools may lead to growth defects and oncogenesis. Upon treatment of cancer cells with therapeutic agents, changes in the canonical dNTPs levels may provide critical information for evaluating drug response and mode ...
Huan, C. Y. +3 more
openaire +3 more sources

