Silver-catalysed azide–alkyne cycloaddition (AgAAC): assessing the mechanism by density functional theory calculations [PDF]
Royal Society Open Science, 2016 ‘Click reactions’ are the copper catalysed dipolar cycloaddition reaction of azides and alkynes to incorporate nitrogens into a cyclic hydrocarbon scaffold forming a triazole ring.
Biswadip Banerji +6 more
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CBT‐Cys click reaction for optical bioimaging in vivo
View, 2023 Derived from the D‐luciferin regeneration pathway in firefly body, the click condensation reaction between 2‐cyanobenzothiazole (CBT) and D‐cysteine (Cys) (CBT‐Cys click reaction) possesses unique advantages, including superior biocompatibility, high ...
Xinyi Hu +5 more
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Designer Reagents for Mass Spectrometry-Based Proteomics: Clickable Cross-Linkers for Elucidation of Protein Structures and Interactions [PDF]
, 2012 We present novel homobifunctional amine-reactive clickable cross-linkers (CXLs) for investigation of three-dimensional protein structures and protein–protein interactions (PPIs).
Agnew, Heather D. +11 more
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Click Reactions in Medicinal Chemistry
Pharmaceuticals, 2023 Two decades after K [...]
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Scientific Reports, 2023 A widely used approach for protein conjugation is through the lysine residues reacting with NHS- or other active esters. However, it is a challenge to precisely control the degree of labeling (DoL) due to the instability of active ester and variability ...
Qiaoqiao Ruan, Cheng Zhao
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Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1 [PDF]
, 2011 We describe the use of iterative in situ click chemistry to design an Akt-specific branched peptide triligand that is a drop-in replacement for monoclonal antibodies in multiple biochemical assays.
Agnew, Heather D. +12 more
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Self-healing metallo-supramolecular hydrogel based on specific Ni2+ coordination interactions of poly(ethylene glycol) with bistriazole pyridine ligands in the main chain [PDF]
, 2020 In this study, a supramolecular hydrogel formed by incorporating the 2,6-bis(1,2,3-triazol-4-yl)-pyridine (btp) ligand in the backbone of a polymer prepared by copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) "click" polyaddition reaction of 2,6 ...
Hoogenboom, Richard +2 more
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Synthesis of Terpolymers by Click Reactions [PDF]
Chemistry – An Asian Journal, 2011 AbstractWell‐defined polymeric structures were easily generated through living polymerization systems, in particular, living radical polymerizations. The polymeric precursors with orthogonal functionalities were subsequently clicked together with single or double (combinatorial) click reactions, such as the copper‐catalyzed azide–alkyne cycloadditions (
Ozcan, Altintas, Umit, Tunca
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Acoustic behavior of melon-headed whales varies on a diel cycle. [PDF]
, 2015 Many terrestrial and marine species have a diel activity pattern, and their acoustic signaling follows their current behavioral state. Whistles and echolocation clicks on long-term recordings produced by melon-headed whales (Peponocephala electra) at ...
Baumann-Pickering, Simone +4 more
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Controlling thermal reactivity with different colors of light [PDF]
, 2017 The ability to switch between thermally and photochemically activated reaction channels with an external stimulus constitutes a key frontier within the realm of chemical reaction control.
Barner-Kowollik, Christopher +2 more
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