Results 21 to 30 of about 425,602 (258)
Application of click chemistry in nanoparticle modification and its targeted delivery
Biomaterials Research, 2018 Background Click chemistry is termed as a group of chemical reactions with favorable reaction rate and orthogonality. Recently, click chemistry is paving the way for novel innovations in biomedical science, and nanoparticle research is a representative ...
Gawon Yi +4 more
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Molecules, 2018 Two conjugation methods using different linkers were applied for the investigation of the spectral characteristics and activity of G-quadruplex (G4)–hemin conjugates.
Joanna Kosman +2 more
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Origin of Orthogonality of Strain‐Promoted Click Reactions [PDF]
Chemistry – A European Journal, 2015 AbstractSite‐specific labeling of biomolecules is rapidly advancing due to the discovery of novel mutually orthogonal reactions. Quantum chemistry studies have also increased our understanding of their relative rates, although these have until now been based on highly simplified reactants.
Wagner Johannes A. +4 more
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Exploration of Optical Properties of Novel Pyrene Derivatives Modified by Click Functionalization
Crystals, 2022 A simple synthetic method was designed, in which the Sonogashira coupling reaction and [2+2] cycloaddition click reaction with high yield were performed on 1-bromopyrene to obtain several novel pyrene derivatives.
Yang Yu +7 more
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A dark intermediate in the fluorogenic reaction between tetrazine fluorophores and trans-cyclooctene
Biophysical Reports, 2022 Fluorogenic labeling via bioorthogonal tetrazine chemistry has proven to be highly successful in fluorescence microscopy of living cells. To date, trans-cyclooctene (TCO) and bicyclonyne have been found to be the most useful substrates for live-cell ...
Felix Hild +4 more
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Click histochemistry for whole-mount staining of brain structures
MethodsX, 2019 Labeling of the replicating DNA with synthetic thymidine analogs is commonly used for marking the dividing cells. However, until now this method has only been applied to histological sections.
Alexander A. Lazutkin +2 more
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Pharmaceuticals, 2023 The innovative design of a triarylborane (TB)-dye with one NMe2-alkylated (propargylated) group and one NMe2 group yielded a system that is both an NMe2 π-donor and an inductive NMe2-alkyl cationic acceptor.
Marta Jurković +4 more
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“Click” reactions in polysaccharide modification [PDF]
Progress in Polymer Science, 2016 Abstract Polysaccharide chemistry is enjoying accelerating development thanks to advances in synthetic techniques, biochemistry and solvents, which enable polysaccharide materials to be useful in a variety of demanding applications. Among the synthetic advances, click chemistry has reconfigured the realm of polysaccharide modification that previously
Xiangtao Meng, Kevin J. Edgar
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Click-to-Chelate: Development of Technetium and Rhenium-Tricarbonyl Labeled Radiopharmaceuticals
Molecules, 2013 The Click-to-Chelate approach is a highly efficient strategy for the radiolabeling of molecules of medicinal interest with technetium and rhenium-tricarbonyl cores.
Thomas L. Mindt, Christiane A. Kluba
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Aggregate, 2023 Alkyne‐based click polymerizations have been nurtured into a powerful synthetic technique for the preparation of new polymers with advanced structures and versatile properties.
Xinyao Fu, Anjun Qin, Ben Zhong Tang
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