The Use of Click-Type Reactions in the Preparation of Thermosets [PDF]
Click chemistry has emerged as an effective polymerization method to obtain thermosets with enhanced properties for advanced applications. In this article, commonly used click reactions have been reviewed, highlighting their advantages in obtaining homogeneous polymer networks.
Konuray, Ali Osman +4 more
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Supramolecular Construction of a Highly Elongated π-Conjugated Structure in the Solid State: Metal-Free Click Reaction Guided by C-H Hydrogen Bonding [PDF]
A planned topochemical azide-alkyne cycloaddition is developed in the organic solid state to generate a highly elongated π-conjugated 1,2,3-triazole by a metal-free click reaction.
Amy, Charles +3 more
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The development of functional materials for tumor immunogenicity enhancement is desirable for overcoming the low therapeutic efficiency and easy metastasis during tumor treatments.
Kaihong Du +19 more
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Redox-Click Chemistry for Disulfide Formation from Thiols [PDF]
The dynamic disulfide linkage plays a vital role in various biological processes as well as drugs and biomaterials. Oxidation of thiols is a widely utilized approach for disulfide synthesis; however, achieving both optimal reactivity and selectivity ...
Xiaohe, Zhang +19 more
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Click Reactions in Medicinal Chemistry
Two decades after K [...]
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Click to learn, learn to click: Undergraduate Synthetic Organic Chemistry experiments [PDF]
The optimization of an undergraduate experiment for Organic Chemistry students is described to explore the concept of click chemistry. The preparation of a terminal fluorescent alkyne and an organic azide is reported consisting of simple steps. These are
Francisco, Santoyo-Gonzalez +3 more
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Brønsted base-catalyzed assembly of sulfochromeno [4,3-b] pyrrolidines via tandem [3+2] cycloaddition-SuFEx click reaction of ethenesulfonyl fluorides and azomethine ylides [PDF]
The synthesis of sulfochromeno [4,3-b] pyrrolidines is described. Under the catalysis of 20 mol% Brønsted base and using 4Å molecular sieves as HF scavenger, imines derived from salicylaldehydes and diethyl aminomalonate react with ethenesulfonyl ...
Qichao, Zhang +4 more
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Intramolecular bridges formed by photoswitchable click amino acids
Photoswitchable click amino acids (PSCaa) are amino acids bearing a side chain consisting of a photoswitchable unit elongated with a functional group that allows for a specific click reaction, such as an alkene that can react with the thiol group of a ...
Christian Hoppmann +2 more
doaj +1 more source
A widely used approach for protein conjugation is through the lysine residues reacting with NHS- or other active esters. However, it is a challenge to precisely control the degree of labeling (DoL) due to the instability of active ester and variability ...
Qiaoqiao Ruan, Cheng Zhao
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Application of click chemistry in nanoparticle modification and its targeted delivery
Background Click chemistry is termed as a group of chemical reactions with favorable reaction rate and orthogonality. Recently, click chemistry is paving the way for novel innovations in biomedical science, and nanoparticle research is a representative ...
Gawon Yi +4 more
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