Results 21 to 30 of about 436,100 (303)
The Carbodiimide Click Reaction Provides Rapid and Conver-gent Access to Aminotriazoloquinazolines
, 2022 A novel, convergent synthesis of aminotriazoloquinazolines is reported. These heterocycles are reliably prepared via a “click” reaction between readily available aryl carbodiimides and acyl hydrazides.
Aaron, Sather +3 more
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Click Reactions in Medicinal Chemistry
Pharmaceuticals, 2023 Two decades after K [...]
openaire +3 more sources
Scientific Reports, 2023 A widely used approach for protein conjugation is through the lysine residues reacting with NHS- or other active esters. However, it is a challenge to precisely control the degree of labeling (DoL) due to the instability of active ester and variability ...
Qiaoqiao Ruan, Cheng Zhao
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Organotitanium Click Chemistry
, 2023 The click chemistry of titanium exemplified by the “green” [3+2] cycloaddition of the [Ti-N3] moiety with nitriles RCN to form a tetrazole ligand, is currently limited in scope, but the future of this open and wide field is bright, full of promising ...
Gregory, Arzoumanidis
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, 2022 In their Comment (Huang, T.; Granick, S. ChemRxiv 2022) on two related publications (J. Am. Chem. Soc. 2021, 143, 20884-20890; J. Am. Chem. Soc. 2022, 144, 1380-1388), Huang et al.
Jaime, Agudo-Canalejo +3 more
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Intramolecular bridges formed by photoswitchable click amino acids
Beilstein Journal of Organic Chemistry, 2012 Photoswitchable click amino acids (PSCaa) are amino acids bearing a side chain consisting of a photoswitchable unit elongated with a functional group that allows for a specific click reaction, such as an alkene that can react with the thiol group of a ...
Christian Hoppmann +2 more
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Application of click chemistry in nanoparticle modification and its targeted delivery
Biomaterials Research, 2018 Background Click chemistry is termed as a group of chemical reactions with favorable reaction rate and orthogonality. Recently, click chemistry is paving the way for novel innovations in biomedical science, and nanoparticle research is a representative ...
Gawon Yi +4 more
doaj +1 more source
Molecules, 2018 Two conjugation methods using different linkers were applied for the investigation of the spectral characteristics and activity of G-quadruplex (G4)–hemin conjugates.
Joanna Kosman +2 more
doaj +1 more source
Click-Ready Perfluorocarbon Nanoemulsion for 19F MRI and Multimodal Cellular Detection
, 2021 We describe an in vivo imaging probe platform that is readily modifiable to accommodate binding of different molecular targeting moieties and payloads for multimodal image generation.
Hongyan Xu (29047) +7 more
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Exploration of Optical Properties of Novel Pyrene Derivatives Modified by Click Functionalization
Crystals, 2022 A simple synthetic method was designed, in which the Sonogashira coupling reaction and [2+2] cycloaddition click reaction with high yield were performed on 1-bromopyrene to obtain several novel pyrene derivatives.
Yang Yu +7 more
doaj +1 more source