Results 41 to 50 of about 28,418 (220)
Unnatural Amino Acid Incorporation into Virus-Like Particles [PDF]
, 2008 Virus-like particles composed of hepatitis B virus (HBV) or bacteriophage Qβ capsid proteins have been labeled with azide- or alkyne-containing unnatural amino acids by expression in a methionine auxotrophic strain of E. coli.
Brown, Steven +11 more
core +2 more sources
Advanced Functional Materials, EarlyView.Fibrous benzenetrispeptide (BTP) hydrogels, fabricated via strain‐promoted azide‐alkyne cycloaddition (SPAAC) crosslinking, form robust, bioinert networks. These hydrogels can support 3D cell culture, where cell viability and colony growth depend on the fiber content.
Ceren C. Pihlamagi +5 more
wiley +1 more source
Angewandte Chemie, EarlyView.We developed a novel domino polymerization to synthesize reductively degradable poly(disulfide)s with tunable side chains. A novel monomer bearing thiolactone and pyridyl disulfide groups reacts with various amines, enabling continuous ring‐opening and disulfide exchange.
Yukiya Kitayama +2 more
wiley +2 more sources
Clickable azide-functionalized bromoarylaldehydes – synthesis and photophysical characterization
Beilstein Journal of Organic Chemistry, 2020 Herein, we present a facile synthesis of three azide-functionalized fluorophores and their covalent attachment as triazoles in Huisgen-type cycloadditions with model alkynes.
Dominik Göbel +3 more
doaj +1 more source
“One-pot” dispersion ATRP and alkyne-azide Huisgen’s 1,3-dipolar cycloaddition in supercritical carbon dioxide: towards the formation of functional microspheres [PDF]
, 2010 Functional polymers were successfully prepared in scCO2 by combining alkyne-azide 1,3-dipolar Huisgen’s cycloaddition and dispersion ATRP in a “one pot” process using new perfluorinated polymeric amino-based ligands that had a dual role, i.e.
Calberg, Cédric +3 more
core +1 more source
Color Routing and Beam Steering of Single‐Molecule Emission with a Spherical Silicon Nanoantenna
Advanced Functional Materials, EarlyView.We experimentally demonstrate broadband directional emission from single molecules using a single spherical silicon nanoparticle assembled via DNA origami. By varying nanoparticle (NP) size and emitter position, we achieve unidirectional emission, beam steering, and color routing at the nanoscale, revealing modal interference as the underlying ...
María Sanz‐Paz +9 more
wiley +1 more source
SynOpen, 2018 A range of bis-heterocyclic derivatives based on novel morpholinone and triazole heterocycles was prepared from iodo-morpholinone. The key step in our strategy is a one-pot procedure based upon copper-catalysed alkyne-azide cycloaddition (CuAAC) from ...
A. Mayooufi +2 more
doaj +1 more source
Chemoenzymatic Synthesis of Triazololactams Structurally Related to Pancratistatin [PDF]
, 2017 Four tricyclic lactams that structurally resemble alkaloids with the pancratistatin skeleton were synthetized from bromobenzene by a chemoenzymatic strategy.
Bastida +48 more
core +1 more source
Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies
Advanced Healthcare Materials, EarlyView.Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best +5 more
wiley +1 more source
Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations
Angewandte Chemie, EarlyView.The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach +4 more
wiley +2 more sources