Results 21 to 30 of about 12,849 (199)

Toward Long-Term-Dispersible, Metal-Free Single-Chain Nanoparticles

Nanomaterials, 2023
We report herein on a new platform for synthesizing stable, inert, and dispersible metal-free single-chain nanoparticles (SCNPs) via intramolecular metal-traceless azide–alkyne click chemistry.
Agustín Blázquez-Martín, Ainara Ruiz-Bardillo, Ester Verde-Sesto, Amaia Iturrospe, Arantxa Arbe, José A. Pomposo   +5 more
doaj   +1 more source

Luminescent Lariat Aza-Crown Ether

Molbank, 2010
Lariat ethers are interesting recognition motifs in supramolecular chemistry. The synthesis of a luminescent lariat ether with triglycol chain by azide–alkyne (Huisgen) cycloaddition is presented.
Burkhard König, Eva-Maria Rummel, Andreas Späth   +2 more
doaj   +1 more source

Advancements and applications of click chemistry in protein labeling and bioconjugation [PDF]

RSC Advances
Click chemistry has emerged as a versatile and efficient chemical strategy for constructing complex molecules under mild conditions. Its core reaction is copper(i)-catalyzed azide–alkyne cycloaddition (CuAAC), which provides high yields ...
Usman Nazeer, Guoting Qin, Chengzhi Cai
doaj   +1 more source

Luminescent Lariat Aza-Crown Ether Carboxylic Acid

Molbank, 2010
Lariat ethers are interesting recognition motifs in supramolecular chemistry. The synthesis of a luminescent lariat aza-crown ether with a carboxyl group appended by azide-alkyne (Huisgen) cycloaddition is presented.
Burkhard König, Eva-Maria Rummel, Andreas Späth   +2 more
doaj   +1 more source

Peptoids and polyamines going sweet: Modular synthesis of glycosylated peptoids and polyamines using click chemistry

Beilstein Journal of Organic Chemistry, 2013
Sugar moieties are present in a wide range of bioactive molecules. Thus, having versatile and fast methods for the decoration of biomimetic molecules with sugars is of fundamental importance.
Daniel Fürniss, Timo Mack, Frank Hahn, Sidonie B. L. Vollrath, Katarzyna Koroniak, Ute Schepers, Stefan Bräse   +6 more
doaj   +1 more source

Nitrogen-Based Linkers with a Mesitylene Core: Synthesis and Characterization

Molecules, 2021
Mesitylene was used as a core in seven new tritopic nitrogen containing linkers. Three of the linkers, each containing three nitrile groups, were obtained through Suzuki, Sonogashira and Heck-type coupling reactions.
Lucian Gabriel Bahrin, Alina Nicolescu, Sergiu Shova, Narcisa Laura Marangoci, Lucian Mihail Birsa, Laura Gabriela Sarbu   +5 more
doaj   +1 more source

A Genetically Encoded Picolyl Azide for Improved Live Cell Copper Click Labeling

Frontiers in Chemistry, 2021
Bioorthogonal chemistry allows rapid and highly selective reactivity in biological environments. The copper-catalyzed azide–alkyne cycloaddition (CuAAC) is a classic bioorthogonal reaction routinely used to modify azides or alkynes that have been ...
Birthe Meineke, Birthe Meineke, Johannes Heimgärtner, Johannes Heimgärtner, Alexander J. Craig, Michael Landreh, Lindon W. K. Moodie, Lindon W. K. Moodie, Simon J. Elsässer, Simon J. Elsässer   +9 more
doaj   +1 more source

Dinuclear Copper(I) Thiodiacetate Complex-Mediated Expeditious Synthesis of the Chlorine-Containing Cyclen-Cored 36-Glucose-Coated Glycodendrimer

Journal of Chemistry, 2021
High-sugar-tethered glycodendrimers are a remarkable tool in glycobiology for the investigation of carbohydrate-protein interaction using its multivalency property.
Anand K. Agrahari, Sunil Kumar, Anindra Sharma, Vinod K. Tiwari   +3 more
doaj   +1 more source

Incorporation of Spin Labels and Paramagnetic Tags for Magnetic Resonance Studies Using Cycloaddition Reactions as a Tool

Reactions
The cycloaddition reaction is one of the most common reactions in organic chemistry. It has been applied in various fields. Herein, we focus on the application of cycloaddition reactions in investigating biological molecules and materials using magnetic ...
Amarendra Nath Maity, Amiya Kumar Medda, Shyue-Chu Ke   +2 more
doaj   +1 more source

Sydnone-modified nucleosides as versatile tools for bioorthogonal post-synthetic functionalization of antisense oligonucleotides [PDF]

RSC Chemical Biology
The development of efficient bioconjugation methods is essential for enhancing the therapeutic potential of oligonucleotides, especially antisense oligonucleotides (ASOs).
Alexandra Bristiel, Alexandre Khuu, Mathilde Poulet, Frédéric Taran, Dominique Urban, Raphaël Guignard, Dominique Guianvarc’h   +6 more
doaj   +1 more source