Results 21 to 30 of about 28,418 (220)

Huisgen-based conjugation of water-soluble porphyrins to deprotected sugars: Towards mild strategies for the labelling of glycans [PDF]

open access: yes, 2014
Fully deprotected alkynyl-functionalised mono- and oligosaccharides undergo CuAAC-based conjugation with water-soluble porphyrin azides in aqueous environments.
Boyle, Ross W.   +4 more
core   +1 more source

Isolation of bis(copper) key intermediates in Cu-catalyzed azide-alkyne "click reaction". [PDF]

open access: yes, 2015
The copper-catalyzed 1,3-dipolar cycloaddition of an azide to a terminal alkyne (CuAAC) is one of the most popular chemical transformations, with applications ranging from material to life sciences.
Bertrand, Guy   +3 more
core   +2 more sources

Luminescent Lariat Aza-Crown Ether

open access: yesMolbank, 2010
Lariat ethers are interesting recognition motifs in supramolecular chemistry. The synthesis of a luminescent lariat ether with triglycol chain by azide–alkyne (Huisgen) cycloaddition is presented.
Burkhard König   +2 more
doaj   +1 more source

Luminescent Lariat Aza-Crown Ether Carboxylic Acid

open access: yesMolbank, 2010
Lariat ethers are interesting recognition motifs in supramolecular chemistry. The synthesis of a luminescent lariat aza-crown ether with a carboxyl group appended by azide-alkyne (Huisgen) cycloaddition is presented.
Burkhard König   +2 more
doaj   +1 more source

A Genetically Encoded Picolyl Azide for Improved Live Cell Copper Click Labeling

open access: yesFrontiers in Chemistry, 2021
Bioorthogonal chemistry allows rapid and highly selective reactivity in biological environments. The copper-catalyzed azide–alkyne cycloaddition (CuAAC) is a classic bioorthogonal reaction routinely used to modify azides or alkynes that have been ...
Birthe Meineke   +9 more
doaj   +1 more source

Revealing nascent proteomics in signaling pathways and cell differentiation. [PDF]

open access: yes, 2018
Regulation of gene expression at the level of protein synthesis is a crucial element in driving how the genetic landscape is expressed. However, we are still limited in technologies that can quantitatively capture the immediate proteomic changes that ...
Burlingame, Alma L   +8 more
core   +1 more source

Peptoids and polyamines going sweet: Modular synthesis of glycosylated peptoids and polyamines using click chemistry

open access: yesBeilstein Journal of Organic Chemistry, 2013
Sugar moieties are present in a wide range of bioactive molecules. Thus, having versatile and fast methods for the decoration of biomimetic molecules with sugars is of fundamental importance.
Daniel Fürniss   +6 more
doaj   +1 more source

Evaluation of bicinchoninic acid as a ligand for copper(I)-catalyzed azide-alkyne bioconjugations [PDF]

open access: yes, 2012
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Budisa, Nediljko   +8 more
core   +1 more source

Dinuclear Copper(I) Thiodiacetate Complex-Mediated Expeditious Synthesis of the Chlorine-Containing Cyclen-Cored 36-Glucose-Coated Glycodendrimer

open access: yesJournal of Chemistry, 2021
High-sugar-tethered glycodendrimers are a remarkable tool in glycobiology for the investigation of carbohydrate-protein interaction using its multivalency property.
Anand K. Agrahari   +3 more
doaj   +1 more source

Surface Modification of Melt Extruded Poly(ε-caprolactone) Nanofibers: Toward a New Scalable Biomaterial Scaffold. [PDF]

open access: yes, 2014
A photochemical modification of melt-extruded polymeric nanofibers is described. A bioorthogonal functional group is used to decorate fibers made exclusively from commodity polymers, covalently attach fluorophores and peptides, and direct cell growth ...
Baer, Eric   +5 more
core   +2 more sources

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