A recent overview on the synthesis of 1,4,5-trisubstituted 1,2,3-triazoles
Beilstein Journal of Organic Chemistry, 2021 Diverse strategies for the efficient and attractive synthesis of a wide variety of relevant 1,4,5-trisubstituted 1,2,3-triazole molecules are reported. The synthesis of this category of diverse fully functionalized 1,2,3-triazoles has become a necessary ...
Pezhman Shiri +2 more
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Synthesis of β-triazolylenones via metal-free desulfonylative alkylation of N-tosyl-1,2,3-triazoles
Beilstein Journal of Organic Chemistry, 2021 Desulfonylative alkylation of N-tosyl-1,2,3-triazoles under metal-free conditions leading to β-triazolylenones is reported here. The present study encompasses the synthesis of triazoles with a new substitution pattern in a single step from cyclic 1,3 ...
Soumyaranjan Pati +3 more
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Triazoles and Their Derivatives: Chemistry, Synthesis, and Therapeutic Applications
Frontiers in Molecular Biosciences, 2022 Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Structurally, there are two types of five-membered triazoles: 1,2,3-triazole and 1,2,4-triazole.
Mohammed M. Matin +8 more
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Журнал Белорусского государственного университета: Химия, 2020 The target for antibacterial action of 1,4-di- and 1,4,5-trisubstituted 1H-1,2,3-triazoles against E. coli ATCC 25922 and S. aureus ATCC 6538 was proposed.
Cyril M. Verbilo +4 more
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Photochemical ligand ejection from non-sterically promoted Ru(ii)bis(diimine) 4,4′-bi-1,2,3-triazolyl complexes [PDF]
, 2014 Complexes of the form [Ru(diimine)2(btz)]2+ (btz = 1,1′-dibenzyl-4,4′-bi-1,2,3-triazolyl) are observed to undergo photochemical ejection of the btz ligand in the absence of any promotion through steric congestion to generate cis-bis(solvent) complexes ...
Sinopoli, Alessandro +6 more
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Metal-Free Synthesis of 1,5-Disubstituted 1,2,3-Triazoles
, 2021 A three-component synthesis of 1,5-disubstituted 1,2,3-triazoles from α-acetyl-α-diazomethane sulfonamides, primary aliphatic amines, and aromatic aldehydes is presented.
Mikhail Krasavin +9 more
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Synthesis and antitumoral activity of novel biaryl hydroxy-triazole and fluorene-triazole hybrids [PDF]
Exploration of Drug ScienceAim: The development of selective and potent antitumor agents remains a significant challenge. This study aimed to synthesize and evaluate biaryl hydroxy-1,2,3-triazoles and 9H-fluorene-1,2,3-triazole hybrids, inspired by previously identified bioactive ...
David Chafi Zeitune +6 more
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Synthesis and antibacterial evaluation of sulfonamide bridged disubstituted 1,2,3-triazoles
, 2022 In the present study, a series of sulfonamide bridged 1,4-disubstituted 1,2,3-triazoles have been synthesized in good yield via click reaction between sulfonamide linked terminal alkynes and in situ prepared 2/3/4-azidobenzenesulfonamides.
C. P. Kaushik (7494545) +1 more
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, 2022 NH-1,2,3-Triazoles undergo a ring cleavage in reactions with fluorinated acid anhydrides (trifluoroacetic, difluoroacetic, chlorodifluoroacetic, and pentafluoropropionic anhydrides) by nitrogen acylation and acid-mediated triazole ring opening ...
Petr Beier (1748218) +3 more
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Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition [PDF]
, 2011 A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the ...
Krim, Jamal +5 more
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