Results 41 to 50 of about 43,142 (242)

Cobalt‐Catalyzed C─N Bond Formation via Metal‐Hydride Hydrogen Atom Transfer (MHAT)

Angewandte Chemie, EarlyView.
Cobalt‐catalyzed metal‐hydride hydrogen atom transfer (Co‐MHAT) converts simple alkenes into C─N bonds under mild, near‐neutral conditions. A shared Co─H‐initiated radical/organocobalt intermediate is channeled into radical trapping, radical‐polar crossover, or radical ligand transfer, unifying hydroamination, hydroazidation, hydroamidation, and remote
Arman Khosravi, Ming‐Yu Ngai
wiley   +2 more sources

Preparation of Quinoline-2,4-dione Functionalized 1,2,3-Triazol-4-ylmethanols, 1,2,3-Triazole-4-carbaldehydes and 1,2,3-Triazole-4-carboxylic Acids

Acta Chimica Slovenica, 2020
(1-(2,4-Dioxo-1,2,3,4-tetrahydroquinolin-3-yl)-1H-1,2,3-triazol-4-yl)methyl acetates substituted on nitrogen atom of quinolinedione moiety with propargyl group or (1-substituted 1H-1,2,3-triazol-4-yl)methyl group, which are available from the appropriate 3-(4-hydroxymethyl-1H-1,2,3-triazol-1-yl)quinoline-2,4(1H,3H)-diones unsubstituted on quinolone ...
Milićević, David, Kimmel, Roman, Urankar, Damijana, Pevec, Andrej, Kosmrlj, Janez, Kafka, Stanislav   +5 more
openaire   +5 more sources

Atroposelective Pd(0)‐Catalyzed Direct Intermolecular C─H Arylation of Thiazole N‐Oxides Provides Access to Heterobiaryls

Angewandte Chemie, EarlyView.
An enantioselective Pd(0)‐catalysed arylation at the C4‐position of thiazole N‐oxides directly forges the atropochiral heterobiaryl axis. A tailored point‐ and axially chiral monodentate phosphine ensures high reactivities along with a tight stereocontrol.
Vitalii Smal, Nicolai Cramer
wiley   +2 more sources

Microwave assisted metal-free approach to access 1,2,3-triazoles through multicomponent synthesis

Current Research in Green and Sustainable Chemistry, 2020
The work illustrates multicomponent reaction of aldehydes, nitroalkanes and sodium azide for the metal-free synthesis of N-unsubstituted-1,2,3-triazoles using anthranilic acid as an organocatalyst under microwave irradiation. This is the first ever green
Anirban Garg, Diganta Sarma, Abdul Aziz Ali   +2 more
doaj   +1 more source

1,2,3-Triazoles

, 2008
Rapid progress in the synthetic application of benzotriazole derivatives in the last 20 years has resulted in over 1000 scientific papers on the subject. This fact is reflected in Section 5.01.7, which involves almost a half of the volume of this chapter. The section is arranged according to hybridization of the C-α atom and atomic numbers of the atoms
Rachwal, S., Katritzky, A.R.
openaire   +1 more source

Imidazo[1,2‐b]Pyrazole‐1,2,4‐oxadiazole Linked 1,2,3‐Triazoles: Synthesis, Antibacterial, Biofilm, and In Silico Studies [PDF]

Chem Biodivers
A collection of innovative imidazo[1,2‐b]pyrazole–1,2,4‐oxadiazole–1,2,3‐triazole hybrids was conceived via the molecular hybridization of bioactive pharmacophores and produced via a CuAAC methodology. The synthesized compounds exhibited strong antibacterial and antibiofilm properties against gram‐positive bacteria.
Murahari S, Siddoju K.
europepmc   +2 more sources

Alkyne-Azide Cycloaddition Catalyzed by Silver Chloride and “Abnormal” Silver N-Heterocyclic Carbene Complex

The Scientific World Journal, 2013
A library of 1,2,3-triazoles was synthesized from diverse alkynes and azides using catalytic amounts of silver chloride instead of copper compounds. In addition, a novel “abnormal” silver N-heterocyclic carbene complex was tested as catalyst in this ...
Aldo I. Ortega-Arizmendi, Eugenia Aldeco-Pérez, Erick Cuevas-Yañez   +2 more
doaj   +1 more source

Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles

Molecules, 2016
Palladium(II) acetate, in combination with triphenylphosphine, catalyzes direct arylation of 1,4-disubstituted 1,2,3-triazoles effectively. This C–H arylation reaction provides facile access to fully substituted triazoles with well-defined regiochemistry.
Chengwei Zhang, Lin You, Chuo Chen
doaj   +1 more source

Synthesis of new 1,4-disubstituted 1,2,3-triazoles using the CuAAC reaction and determination of their antioxidant activities

Anais da Academia Brasileira de Ciências, 2021
This study describes the synthesis and antioxidant activity of new 1,4-disubstituted 1,2,3-triazoles. These compounds were generated semi-synthetically using the Cu(I)-catalysed azide-alkyne cycloaddition (CuAAC) reaction between ethyl 2-azidoacetate and
JOSEFA A. DA CUNHA LIMA, JADSON DE FARIAS SILVA, COSME S. SANTOS, RODRIGO R.A. CAIANA, MARCÍLIO M. DE MORAES, CLAUDIO A.G. DA CÂMARA, JULIANO C.R. FREITAS   +6 more
doaj   +1 more source

Enzymatic Macrocyclization of 1,2,3‐Triazole Peptide Mimetics [PDF]

Angewandte Chemie International Edition, 2016
AbstractThe macrocyclization of linear peptides is very often accompanied by significant improvements in their stability and biological activity. Many strategies are available for their chemical macrocyclization, however, enzyme‐mediated methods remain of great interest in terms of synthetic utility.
Emilia Oueis, Marcel Jaspars, Nicholas J. Westwood, James H. Naismith   +3 more
openaire   +6 more sources