Results 1 to 10 of about 63,260 (268)

Aromaticities of Five Membered Heterocycles through Dimethyldihydropyrenes Probe by Magnetic and Geometric Criteria

Journal of Chemistry, 2015
Aromaticities of five membered heterocycles, containing up to three heteroatoms, are quantified through the dimethyldihydropyrene (DHP) probe. Bond fixation caused by the fusion of heterocycles to the dimethyldihydropyrene nucleus (DHPN) was measured by ...
Maria, Khurshid Ayub
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Adventures with Heterocycles.

Chemical and Pharmaceutical Bulletin, 2000
Elucidation of mechanisms and discovery of novel reactions are interconnected, as four research chapters from the Munich laboratory demonstrate. 1) In a new opening of the furan ring, 2-methoxyfuran and tetra-acceptor-substituted ethylenes furnish methyl acrylates, which are cis-3-substituted by a cyclopropyl ring that bears the four acceptor groups ...
openaire   +3 more sources

Radiation-driven Destruction of N-heterocycles in the Presence and Absence of Water Ice

The Astrophysical Journal
Simple N -heterocycles are expected to be an abundant class of molecules within the interstellar medium, and increasingly complex heterocycles (e.g., nucleobases) have been detected within meteoritic organic material and in samples returned from the ...
Patrick D. Tribbett, Yukiko Y. Yarnall, Perry A. Gerakines, Reggie L. Hudson, Christopher K. Materese   +4 more
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Polyoxometalate catalysts for the synthesis of N-heterocycles

Polyoxometalates
N-Heterocycle compounds are crucial scaffolds in natural products, synthetic molecules, agricultural chemicals, and pharmaceuticals. Hence, green catalytic systems for the synthesis of N-heterocycles have been widely researched in organic synthesis and ...
Qilong Hu, Ke Li, Xuejiao Chen, Yufeng Liu, Guoping Yang   +4 more
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Synthesis of Oxygen Heterocycles via Aromatic C-O Bond Formation Using Arynes

Molecules, 2015
Most of the synthetic approaches to the benzo-fused heterocycles containing an oxygen atom have involved the use of phenol derivatives as a starting material.
Hideto Miyabe
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An Overview of Saturated Cyclic Ethers: Biological Profiles and Synthetic Strategies

Molecules, 2019
Saturated oxygen heterocycles are widely found in a broad array of natural products and other biologically active molecules. In medicinal chemistry, small and medium rings are also important synthetic intermediates since they can undergo ring-opening and
Qili Lu, Dipesh S. Harmalkar, Yongseok Choi, Kyeong Lee   +3 more
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Visible light mediated intermolecular [3 + 2] annulation of cyclopropylanilines with alkynes

Beilstein Journal of Organic Chemistry, 2014
Intermolecular [3 + 2] annulation of cyclopropylanilines with alkynes is realized using visible light photoredox catalysis, yielding a variety of cyclic allylic amines in fair to good yields.
Theresa H. Nguyen, Soumitra Maity, Nan Zheng   +2 more
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Synthesis, antiproliferative activity, and in silico ADMETox profiling of 4-quinolone-3-carboxamides as selective anticancer agents in cervical cancer cells

Results in Chemistry
The development of selective anticancer agents with improved safety profiles and favorable pharmacokinetic properties remains a major challenge in medicinal chemistry.
Thiago Mota do Vale, Leticia Machado dos Santos, Julio Cesar Thurler-Jr, Milena França Longue, Jordana de Paula Alves, Caio Henrique Pinke Rodrigues, Larissa Silva de Oliveira Mota, Marcela Cristina de Moraes, Vinicius D'Ávila Bitencourt Pascoal, Maria Cecília Bastos Vieira de Souza, Aislan Cristina Rheder Fagundes Pascoal, Fernanda da Costa Santos Boechat   +11 more
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Recent Advances in Indazole-Derived Heterocycles: Synthetic Strategies, Functionalization, and Therapeutic Potential

Journal of Chemistry
Indazole-derived heterocycles have garnered significant attention in recent years due to their versatile chemical structures and wide-ranging biological activities. This review explores the recent progress in the synthesis of indazole-based heterocycles,
Uday V. Bhat, Glanish Jude Martis, Dinesh Chikkanna, Santosh L. Gaonkar   +3 more
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From A Fundamental Study on Hydrogen Bond Network and Chain Mobility in Benzimidazole Model Compounds to Various Designs and Development of Benzimidazole-based Anhydrous Membranes for Proton Exchange Membrane Fuel Cell

Journal of Analytical Science and Technology, 2011
A series of N-containing heterocycles i.e., imidazole and benzimidazole are systematically designed to study how proton transfer in anhydrous system is related to hydrogen bond network and molecular mobility.
Suwabun Chirachanchai, Chatchai Jarumaneeroj, Autchara Pangon   +2 more
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