Results 11 to 20 of about 2,673 (166)

Azides in the Synthesis of Various Heterocycles

Molecules, 2022
In this review, we focus on some interesting and recent examples of various applications of organic azides such as their intermolecular or intramolecular, under thermal, catalyzed, or noncatalyzed reaction conditions.
AbdElAziz A. Nayl, Ashraf A. Aly, Wael A. A. Arafa, Ismail M. Ahmed, Ahmed I. Abd-Elhamid, Esmail M. El-Fakharany, Mohamed A. Abdelgawad, Hendawy N. Tawfeek, Stefan Bräse   +8 more
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Heterocycles Synthesis at Carbonylation of Acetylenic Compounds

Eurasian Chemico-Technological Journal, 2003
The carbonylation of unsaturated hydrocarbons, alcohols, organic halides and other substrates catalyzed by transition metals, salts of transition metals and organometallic complexes is a wide used synthesis method of new carbonyl, carboxyl and alkoxy ...
S.A. Vizer, K.B. Yerzhanov
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An electrochemical gram-scale protocol for pyridylation of inert N-heterocycles with cyanopyridines

STAR Protocols, 2022
Summary: Here, we present a protocol to decyanopyridate inert N-heterocycles access to N-fused heterocycles via the mechanism of dual proton-coupled electron transfer (PCET).
Cong Niu, Jianjing Yang, Kelu Yan, Jiafang Xie, Wei Jiang, Bingwen Li, Jiangwei Wen   +6 more
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Phosphorus-Sulfur Heterocycles Incorporating an O-P(S)-O or O-P(S)-S-S-P(S)-O Scaffold: One-Pot Synthesis and Crystal Structure Study

Molecules, 2017
A new one-pot preparative route was developed to synthesize novel organophosphorus-sulfur heterocycles via the reaction of the four-membered ring thionation reagent [2,4-diferrocenyl-1,3,2,4-diathiadiphosphetane 2,4-disulfide (FcLR, a ferrocene analogue ...
Guoxiong Hua, Kate Davidson, David B. Cordes, Junyi Du, Alexandra M. Z. Slawin, J. Derek Woollins   +5 more
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Enantioselective construction of six- and seven-membered triorgano-substituted silicon-stereogenic heterocycles

Nature Communications, 2021
Enantioenriched medium-sized silicon-stereogenic heterocycles are in high demand due to the potential use in functional materials. Here, the authors show a rhodium-catalyzed enantioselective synthesis of six- and seven-membered tri-organosubstituted ...
Shuyou Chen, Delong Mu, Pei-Lin Mai, Jie Ke, Yingzi Li, Chuan He   +5 more
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A Brief Review on the Synthesis of the N-CF₃ Motif in Heterocycles

Molecules, 2023
The trifluoromethyl group is widely recognized for its significant role in the fields of medicinal chemistry and material science due to its unique electronic and steric properties that can alter various physiochemical properties of the parent molecule ...
Zizhen Lei, Wenxu Chang, Hong Guo, Jiyao Feng, Zhenhua Zhang   +4 more
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In silico screening of drug-like molecules for the treatment of cardiovascular diseases on the basis of five-membered privileged heterocycles

Фармацевтичний журнал, 2019
Among various heterocyclic systems, the derivatives of five-membered heterocycles are of special interest. Most of the above mentioned heterocycles are treatred as so-called privileged structures in modern medicinal chemistry.
І. V. Drapak
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N-tert-Butanesulfinyl imines in the asymmetric synthesis of nitrogen-containing heterocycles

Beilstein Journal of Organic Chemistry, 2021
The synthesis of nitrogen-containing heterocycles, including natural alkaloids and other compounds presenting different types of biological activities have proved to be successful employing chiral sulfinyl imines derived from tert-butanesulfinamide ...
Joseane A. Mendes, Paulo R. R. Costa, Miguel Yus, Francisco Foubelo, Camilla D. Buarque   +4 more
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Catalytic asymmetric formal nucleophilic C2-substitution of indoles via C2-umpolung toward 2,3’-bisindole atropisomers

Nature Communications
The electrophilic substitution of indoles represents the predominant functionalization strategy. However, due to the electron-rich nature of the indole scaffold, catalytic asymmetric nucleophilic substitution remains markedly underdeveloped—presenting ...
Cong-Hui Gao, Xian-Yang Yu, Bo-Xuan Yao, Hao-Lei Yu, Shao-Fei Ni, Wei Tan, Feng Shi   +6 more
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4-Membered Ring Carbocations: A Positive Development in the Synthesis of 3,3-Disubstituted Oxetanes and Azetidines

CHIMIA, 2023
4-Membered heterocycles are low molecular weight polar scaffolds with intriguing potential for drug discovery. Despite their unquestionable value, methods to access such heterocycles remain scant.
Juan J. Rojas, James A. Bull
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